Modeling human colon cancer in rodents using a food-borne carcinogen, PhIP. (Q36289538)

13 August 2017

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title

Modeling human colon cancer in rodents using a food-borne carcinogen, PhIP. (English)

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13 August 2017

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Hitoshi Nakagama

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13 August 2017

Masako Ochiai

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13 August 2017

Masako Nakanishi

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13 August 2017

publication date

1 October 2005

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13 August 2017

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13 August 2017

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13 August 2017

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13 August 2017

page(s)

627-636

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Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland

13 August 2017

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How we should deal with unavoidable exposure of man to environmental mutagens: cooked food mutagen discovery, facts and lessons for cancer prevention

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DNA modification by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats

21 January 2018

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Effects of gender and species on spectra of mutation induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the lacI transgene

21 January 2018

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Interpretation of mutational spectra from different genes: analyses of PhIP-induced mutational specificity in the lacI and cII transgenes from colon of Big Blue rats

21 January 2018

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Agreement of mutational characteristics of heterocyclic amines in lacI of the Big Blue mouse with those in tumor related genes in rodents

21 January 2018

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The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity

21 January 2018

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Efficient induction of rat large intestinal tumors with a new spectrum of mutations by intermittent administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in combination with a high fat diet

21 January 2018

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Efficient method for rapid induction of aberrant crypt foci in rats with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

21 January 2018

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Reduction in formation of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP)-induced aberrant crypt foci in the rat colon by docosahexaenoic acid (DHA)

21 January 2018

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More frequent beta-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats

21 January 2018

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A rat colon cancer model induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, PhIP.

21 January 2018

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Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess beta-catenin gene mutations and increases immunoreactivity for beta-catenin, c

21 January 2018

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Characterization of Dysplastic Aberrant Crypt Foci in the Rat Colon Induced by 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine

21 January 2018

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

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21 January 2018

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Absence of p53 mutations in rat colon tumors induced by 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole, 2-amino-3-methylimidazo[4,5-f]quinoline, or 2-amino-1-methyl-6-phenylimidazo]4,5-b]pyridine

21 January 2018

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Effect of dietary fat on codon 12 and 13 Ha-ras gene mutations in 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine–induced rat mammary gland tumors

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21 January 2018

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Comparative genomic hybridization analysis of PhIP-induced mammary carcinomas in rats reveals a cytogenetic signature

21 January 2018

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Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

21 January 2018

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Wnt signalling induces maturation of Paneth cells in intestinal crypts

21 January 2018

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Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings

21 January 2018

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Differential staining of dysplastic aberrant crypt foci in the colon facilitates prediction of carcinogenic potentials of chemicals in rats

21 January 2018

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Strain differences of rats in the susceptibility to aberrant crypt foci formation by 2-amino-1-methyl-6-phenylimidazo- [4,5-b]pyridine: no implication of Apc and Pla2g2a genetic polymorphisms in differential susceptibility

21 January 2018

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Meat consumption and risk of colorectal cancer

21 January 2018

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Carcinogenic risk assessment of MeIQx and PhIP in a newborn mouse two-stage tumorigenesis assay.

21 January 2018

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Existence of a threshold for induction of aberrant crypt foci in the rat colon with low doses of 2-amino-1-methyl-6-phenolimidazo[4,5-b]pyridine

21 January 2018

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10.1111/J.1349-7006.2005.00107.X

21 January 2018

Identifiers

DOI

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13 August 2017

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