Study of GABA in Healthy Volunteers: Pharmacokinetics and Pharmacodynamics (Q36265459)

13 August 2017

Study of GABA in Healthy Volunteers: Pharmacokinetics and Pharmacodynamics (English)

1 reference

13 August 2017

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1 reference

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8 June 2020

Junfeng Li

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8 June 2020

Zhaoyun Zhang

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8 June 2020

Xiaoxia Liu

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8 June 2020

Yi Wang

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8 June 2020

Fei Mao

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8 June 2020

Junjun Mao

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8 June 2020

Xiaolan Lu

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8 June 2020

Dongdong Jiang

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8 June 2020

Yun Wan

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8 June 2020

Jia-Ying Lv

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8 June 2020

Guoying Cao

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8 June 2020

Jing Zhang

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8 June 2020

Naiqing Zhao

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8 June 2020

Mark Atkinson

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8 June 2020

Dale L Greiner

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8 June 2020

Gerald J Prud'homme

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8 June 2020

Yiming Li

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8 June 2020

Qinghua Wang

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8 June 2020

language of work or name

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10 November 2015

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Frontiers in Pharmacology

13 August 2017

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8 June 2020

volume

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8 June 2020

page(s)

260

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GABA protects pancreatic beta cells against apoptosis by increasing SIRT1 expression and activity

8 June 2020

cites work

1 reference

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Combined therapy with GABA and proinsulin/alum acts synergistically to restore long-term normoglycemia by modulating T-cell autoimmunity and promoting β-cell replication in newly diabetic NOD mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

γ-Aminobutyric acid regulates both the survival and replication of human β-cells

30 September 2017

1 reference

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30 September 2017

1 reference

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Pharmacology, physiology, and mechanisms of incretin hormone action

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

Immune therapy in type 1 diabetes mellitus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

Clinical impact of glycated albumin as another glycemic control marker

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

Insulin as a physiological modulator of glucagon secretion

30 September 2017

1 reference

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Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans

30 September 2017

1 reference

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Gamma-aminobutyric acid up- and downregulates insulin secretion from beta cells in concert with changes in glucose concentration

30 September 2017

1 reference

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Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system

30 September 2017

1 reference

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The neurotransmitters glycine and GABA stimulate glucagon-like peptide-1 release from the GLUTag cell line.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

Trophic actions of GABA on neuronal development

30 September 2017

1 reference

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Regulated exocytosis of GABA-containing synaptic-like microvesicles in pancreatic beta-cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

The Metabolism and Functions of [gamma]-Aminobutyric Acid

30 September 2017

1 reference

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Is there more to GABA than synaptic inhibition?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

Glucose-inhibition of glucagon secretion involves activation of GABAA-receptor chloride channels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

Glucose inhibition of glucagon secretion from rat alpha-cells is mediated by GABA released from neighboring beta-cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

GABA promotes human β-cell proliferation and modulates glucose homeostasis.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

GABA protects human islet cells against the deleterious effects of immunosuppressive drugs and exerts immunoinhibitory effects alone

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

Gamma-aminobutyric acid inhibits T cell autoimmunity and the development of inflammatory responses in a mouse type 1 diabetes model

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

GABA in the endocrine pancreas: cellular localization and function in normal and diabetic rats

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4639630

Glycated albumin is a better glycemic indicator than glycated hemoglobin values in hemodialysis patients with diabetes: effect of anemia and erythropoietin injection

22 September 2018

1 reference

12 December 2020

Is plasma GABA of peripheral origin?

1 reference

12 December 2020

Glucagon-like peptide-1 stimulates GABA formation by pancreatic beta-cells at the level of glutamate decarboxylase

1 reference

12 December 2020

Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man

1 reference

12 December 2020

Identifiers

DOI

10.3389/FPHAR.2015.00260

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26617516%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26617516%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

PubMed publication ID

26617516

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26617516%20AND%20SRC:MED&resulttype=core&format=json