Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice (Q36182530)

12 August 2017

Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice (English)

1 reference

12 August 2017

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Stephen B Wheatcroft

1 reference

12 August 2017

Mark T Kearney

1 reference

12 August 2017

David J Beech

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Hema Viswambharan

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Nadira Yuldasheva

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Keith M Channon

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Richard M Cubbon

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12 August 2017

Helen Imrie

1 reference

12 August 2017

Stacey Galloway

1 reference

12 August 2017

Afroze Abbas

1 reference

12 August 2017

Shouhong Xuan

1 reference

12 August 2017

Anna Skromna

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12 August 2017

V Kate Gatenby

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12 August 2017

T Simon Futers

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12 August 2017

Piruthivi Sukumar

1 reference

12 August 2017

Matthew Gage

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12 August 2017

Jessica Smith

1 reference

12 August 2017

Sheik Taqweer Rashid

1 reference

12 August 2017

Peter J Grant

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12 August 2017

language of work or name

English

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publication date

25 June 2012

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full work available at URL

12 August 2017

http://eprints.whiterose.ac.uk/111262/

content deliverer

White Rose Research Online

Creative Commons Attribution-NonCommercial 3.0 Unported

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published in

Diabetes

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12 August 2017

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12 August 2017

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12 August 2017

2359-2368

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

12 August 2017

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Increasing circulating IGFBP1 levels improves insulin sensitivity, promotes nitric oxide production, lowers blood pressure, and protects against atherosclerosis

1 reference

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The insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endothelium

1 October 2017

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Insulin resistance impairs circulating angiogenic progenitor cell function and delays endothelial regeneration

1 October 2017

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The role of IGF-1 resistance in obesity and type 2 diabetes-mellitus-related insulin resistance and vascular disease

1 October 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Resident endothelial cells surrounding damaged arterial endothelium reendothelialize the lesion

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo

1 October 2017

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Abnormal angiogenesis in diabetic nephropathy.

1 October 2017

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Cardiovascular actions of insulin

1 October 2017

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Hybrid receptors formed by insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) have low insulin and high IGF-1 affinity irrespective of the IR splice variant

1 October 2017

1 reference

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Peripheral arterial disease in patients with diabetes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Endothelial function predicts future development of coronary artery disease: a study of women with chest pain and normal coronary angiograms

1 October 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

The prevalence of diabetic retinopathy among adults in the United States

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Structural biology of insulin and IGF1 receptors: implications for drug design

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

1 October 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Mitogenicity and transforming activity of the insulin-like growth factor-I receptor with mutations in the tyrosine kinase domain.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Endothelial Nox2 overexpression potentiates vascular oxidative stress and hemodynamic response to angiotensin II: studies in endothelial-targeted Nox2 transgenic mice

2 July 2018

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Insulin- and growth factor-resistance impairs vascular regeneration in diabetes mellitus.

2 July 2018

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Human exercise-induced circulating progenitor cell mobilization is nitric oxide-dependent and is blunted in South Asian men.

23 September 2018

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Vascular insulin-like growth factor-I resistance and diet-induced obesity

23 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Effects of neuronal nitric oxide synthase on human coronary artery diameter and blood flow in vivo.

23 September 2018

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Getting away from glucose: stop sugarcoating diabetes

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Effect of endothelium-specific insulin resistance on endothelial function in vivo

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

IGF-1 reduces inflammatory responses, suppresses oxidative stress, and decreases atherosclerosis progression in ApoE-deficient mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Age-dependent impairment of endothelial progenitor cells is corrected by growth-hormone-mediated increase of insulin-like growth-factor-1.

23 September 2018

1 reference

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Preserved glucoregulation but attenuation of the vascular actions of insulin in mice heterozygous for knockout of the insulin receptor

23 September 2018

1 reference

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Ets motifs are necessary for endothelial cell-specific expression of a 723-bp Tie-2 promoter/enhancer in Hprt targeted transgenic mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Diabetes as a risk factor for stroke. A population perspective

23 September 2018

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Targeting of human eNOS promoter to the Hprt locus of mice leads to tissue-restricted transgene expression

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3425420

Hypertension does not account for the accelerated atherosclerosis and development of aneurysms in male apolipoprotein e/endothelial nitric oxide synthase double knockout mice

21 October 2018

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12 December 2020

Increased abundance of insulin/IGF-I hybrid receptors in adipose tissue from NIDDM patients

1 reference

12 December 2020

Relation between age and cardiovascular disease in men and women with diabetes compared with non-diabetic people: a population-based retrospective cohort study

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12 December 2020

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

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12 December 2020

Identifiers

DOI

10.2337/DB11-1494

1 reference

Dimensions Publication ID

12 August 2017

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0 references

0 references

1 reference

12 August 2017

PubMed publication ID

22733797

1 reference