Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma (Q36172671)

12 August 2017

Targeting the miR-221-222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma (English)

1 reference

12 August 2017

1 reference

1 reference

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31 May 2020

1 reference

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31 May 2020

Kenneth C Anderson

1 reference

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31 May 2020

Jian-Jun Zhao

1 reference

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31 May 2020

Zhang-Bo Chu

1 reference

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31 May 2020

Jianhong Lin

1 reference

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31 May 2020

Zhongqiu Wang

1 reference

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31 May 2020

Meng Jiang

1 reference

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31 May 2020

Ming Chen

1 reference

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31 May 2020

Xujun Wang

1 reference

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31 May 2020

Yue Kang

1 reference

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31 May 2020

Yangsheng Zhou

1 reference

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31 May 2020

Melanie E Johncilla

1 reference

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31 May 2020

Yu-Tzu Tai

1 reference

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31 May 2020

Jin Q Cheng

1 reference

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31 May 2020

Antony Letai

1 reference

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31 May 2020

Nikhil C Munshi

1 reference

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31 May 2020

Ruben D Carrasco

1 reference

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31 May 2020

language of work or name

English

0 references

publication date

6 August 2015

1 reference

12 August 2017

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31 May 2020

volume

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31 May 2020

issue

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31 May 2020

page(s)

4384-4397

1 reference

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In vivo murine model of acquired resistance in myeloma reveals differential mechanisms for lenalidomide and pomalidomide in combination with dexamethasone.

31 May 2020

cites work

1 reference

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miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/β-catenin/BCL9 pathway

1 October 2017

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In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma

1 October 2017

1 reference

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Probabilistic orthology analysis of the ATP-binding cassette transporters: implications for the development of multiple drug resistance phenotype

1 October 2017

1 reference

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Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy

1 October 2017

1 reference

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Anti-microRNA-222 (anti-miR-222) and -181B suppress growth of tamoxifen-resistant xenografts in mouse by targeting TIMP3 protein and modulating mitogenic signal.

1 October 2017

1 reference

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A cluster of specified microRNAs in peripheral blood as biomarkers for metastatic non-small-cell lung cancer by stem-loop RT-PCR

1 October 2017

1 reference

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miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTPμ

1 October 2017

1 reference

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MicroRNA Signature Distinguishes the Degree of Aggressiveness of Papillary Thyroid Carcinoma

1 October 2017

1 reference

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MicroRNAs are independent predictors of outcome in diffuse large B-cell lymphoma patients treated with R-CHOP.

1 October 2017

1 reference

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Initial genome sequencing and analysis of multiple myeloma

1 October 2017

1 reference

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miR-221 and miR-222 expression increased the growth and tumorigenesis of oral carcinoma cells

1 October 2017

1 reference

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PUMA is a novel target of miR-221/222 in human epithelial cancers

1 October 2017

1 reference

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Circulating miR‐221 directly amplified from plasma is a potential diagnostic and prognostic marker of colorectal cancer and is correlated with p53 expression

1 October 2017

1 reference

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miRNA profiling along tumour progression in ovarian carcinoma

1 October 2017

1 reference

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MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN

1 October 2017

1 reference

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Molecular mechanisms of nutlin-induced apoptosis in multiple myeloma: evidence for p53-transcription-dependent and -independent pathways

1 October 2017

1 reference

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MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia.

1 October 2017

1 reference

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microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma

1 October 2017

1 reference

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Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling.

1 October 2017

1 reference

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miR-221 overexpression contributes to liver tumorigenesis

1 October 2017

1 reference

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PUMA, a potent killer with or without p53

1 October 2017

1 reference

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Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival

1 October 2017

1 reference

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MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines.

1 October 2017

1 reference

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Sustained activation of ERK1/2 by NGF induces microRNA-221 and 222 in PC12 cells

1 October 2017

1 reference

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Integrative high-resolution microarray analysis of human myeloma cell lines reveals deregulated miRNA expression associated with allelic imbalances and gene expression profiles.

1 October 2017

1 reference

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Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer

1 October 2017

1 reference

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MicroRNA-221/222 negatively regulates estrogen receptor alpha and is associated with tamoxifen resistance in breast cancer

1 October 2017

1 reference

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Dexamethasone-induced apoptotic mechanisms in myeloma cells investigated by analysis of mutant glucocorticoid receptors

1 October 2017

1 reference

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MicroRNAs 221 and 222 bypass quiescence and compromise cell survival

1 October 2017

1 reference

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Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation

1 October 2017

1 reference

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miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1.

1 October 2017

1 reference

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Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer

1 October 2017

1 reference

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MicroRNA expression distinguishes between germinal center B cell-like and activated B cell-like subtypes of diffuse large B cell lymphoma

1 October 2017

1 reference

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

1 October 2017

1 reference

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p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

1 October 2017

1 reference

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Characterization of the MM.1 human multiple myeloma (MM) cell lines: a model system to elucidate the characteristics, behavior, and signaling of steroid-sensitive and -resistant MM cells

1 October 2017

1 reference

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Recent insights into the mechanism of glucocorticosteroid-induced apoptosis

1 October 2017

1 reference

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microRNAs: tiny regulators with great potential

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609291

PUMA induces the rapid apoptosis of colorectal cancer cells

1 October 2017

1 reference

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The bone marrow stromal microenvironment influences myeloma therapeutic response in vitro

1 October 2017

1 reference

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Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

1 October 2017

1 reference

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Genome-wide identification of translationally inhibited and degraded miR-155 targets using RNA-interacting protein-IP.

1 October 2017

1 reference

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miR-221/222 targeting of trichorhinophalangeal 1 (TRPS1) promotes epithelial-to-mesenchymal transition in breast cancer

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609291

Multiple myeloma, version 1.2013.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609291

Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4609291

MiRNAs in follicular thyroid tumors

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26249174

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MicroRNAs expressed during lung cancer development are expressed in human pseudoglandular lung embryogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26249174

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

p53 gene mutations in multiple myeloma are associated with advanced forms of malignancy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26249174

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-15-0457

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26249174%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26249174%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

26249174

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26249174%20AND%20SRC:MED&resulttype=core&format=json