Identification of genes that contribute to the pathogenesis of invasive pneumococcal disease by in vivo transcriptomic analysis (Q36163091)

12 August 2017

Identification of genes that contribute to the pathogenesis of invasive pneumococcal disease by in vivo transcriptomic analysis (English)

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12 August 2017

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Claudia Trappetti

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12 August 2017

Abiodun D Ogunniyi

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12 August 2017

Layla K Mahdi

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12 August 2017

Nadine Verhoeven

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12 August 2017

Daphne Mermans

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12 August 2017

Mark B Van der Hoek

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12 August 2017

Charles D Plumptre

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12 August 2017

James C Paton

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12 August 2017

language of work or name

English

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publication date

9 July 2012

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12 August 2017

Infection and Immunity

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12 August 2017

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12 August 2017

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12 August 2017

3268-3278

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describes a project that uses

12 August 2017

limma

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22 June 2022

https://europepmc.org/article/PMC/3418729

inferred from PubMed Central ID database lookup

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Pneumolysin with low hemolytic activity confers an early growth advantage to Streptococcus pneumoniae in the blood.

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2 October 2017

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Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae.

2 October 2017

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Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates

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Identification of Streptococcus pneumoniae genes specifically induced in mouse lung tissues

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Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies

2 October 2017

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Pneumococcal virulence gene expression and host cytokine profiles during pathogenesis of invasive disease

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Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae.

2 October 2017

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Switch from planktonic to sessile life: a major event in pneumococcal pathogenesis

2 October 2017

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

2 October 2017

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Nasal colonization with Streptococcus pneumoniae includes subpopulations of surface and invasive pneumococci

2 October 2017

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Antibodies to the iron uptake ABC transporter lipoproteins PiaA and PiuA promote opsonophagocytosis of Streptococcus pneumoniae

2 October 2017

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Microarray analysis of pneumococcal gene expression during invasive disease

2 October 2017

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The Ami-AliA/AliB permease of Streptococcus pneumoniae is involved in nasopharyngeal colonization but not in invasive disease.

2 October 2017

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A two-component system that controls the expression of pneumococcal surface antigen A (PsaA) and regulates virulence and resistance to oxidative stress in Streptococcus pneumoniae.

2 October 2017

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From nose to lung: the regulation behind Streptococcus pneumoniae virulence factors

2 October 2017

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Normalization of cDNA microarray data

2 October 2017

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Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factors

2 October 2017

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Differential fluorescence induction analysis of Streptococcus pneumoniae identifies genes involved in pathogenesis

2 October 2017

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

2 October 2017

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Immunization with components of two iron uptake ABC transporters protects mice against systemic Streptococcus pneumoniae infection

2 October 2017

1 reference

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Protection against Streptococcus pneumoniae elicited by immunization with pneumolysin and CbpA.

2 October 2017

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Genome of the Bacterium Streptococcus pneumoniae Strain R6

2 October 2017

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Complete Genome Sequence of a Virulent Isolate of Streptococcus pneumoniae

2 October 2017

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A functional genomic analysis of type 3 Streptococcus pneumoniae virulence

2 October 2017

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Differential fluorescence induction reveals Streptococcus pneumoniae loci regulated by competence stimulatory peptide

2 October 2017

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2 October 2017

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Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae

2 October 2017

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Additive attenuation of virulence of Streptococcus pneumoniae by mutation of the genes encoding pneumolysin and other putative pneumococcal virulence proteins

2 October 2017

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Large-scale identification of virulence genes from Streptococcus pneumoniae.

2 October 2017

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Phase variation in pneumococcal opacity: relationship between colonial morphology and nasopharyngeal colonization

2 October 2017

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Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae

2 October 2017

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Purification and immunogenicity of genetically obtained pneumolysin toxoids and their conjugation to Streptococcus pneumoniae type 19F polysaccharide

2 October 2017

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Pneumococcal histidine triad proteins are regulated by the Zn2+-dependent repressor AdcR and inhibit complement deposition through the recruitment of complement factor H.

2 October 2017

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Tissue-specific contributions of pneumococcal virulence factors to pathogenesis

23 September 2018

1 reference

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Organ-specific models of Streptococcus pneumoniae disease

23 September 2018

1 reference

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Expression of recombinant proteins in a lipid A mutant of Escherichia coli BL21 with a strongly reduced capacity to induce dendritic cell activation and maturation

23 September 2018

1 reference

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A Streptococcus pneumoniae pathogenicity island encoding an ABC transporter involved in iron uptake and virulence

23 September 2018

1 reference

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Competition among Streptococcus pneumoniae for intranasal colonization in a mouse model.

23 September 2018

1 reference

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Antigenome technology: a novel approach for the selection of bacterial vaccine candidate antigens

23 September 2018

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12 December 2020

The genes encoding virulence-associated proteins and the capsule of Streptococcus pneumoniae are upregulated and differentially expressed in vivo

1 reference

12 December 2020

Gene splicing by overlap extension

1 reference

12 December 2020

Differential expression of key pneumococcal virulence genes in vivo

1 reference

12 December 2020

PiuA and PiaA, iron uptake lipoproteins of Streptococcus pneumoniae, elicit serotype independent antibody responses following human pneumococcal septicaemia

1 reference

12 December 2020

Identifiers

DOI

10.1128/IAI.00295-12

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22778095

1 reference