2-Substitution of Adenine Nucleotide Analogues Containing a Bicyclo[3.1.0]hexane Ring System Locked in a Northern Conformation: Enhanced Potency as P2Y1 Receptor Antagonists (Q36128578)

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scientific article published on November 6, 2003

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English	2-Substitution of Adenine Nucleotide Analogues Containing a Bicyclo[3.1.0]hexane Ring System Locked in a Northern Conformation: Enhanced Potency as P2Y1 Receptor Antagonists	scientific article published on November 6, 2003

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists (English)

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12 August 2017

2-Substitution of Adenine Nucleotide Analogues Containing a Bicyclo[3.1.0]hexane Ring System Locked in a Northern Conformation: Enhanced Potency as P2Y1 Receptor Antagonists (English)

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purinergic P2 receptor antagonists

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26 March 2024

molecular medicine

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author name string

Hak Sung Kim

1

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12 August 2017

Michihiro Ohno

2

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12 August 2017

Bin Xu

3

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12 August 2017

Hea Ok Kim

4

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12 August 2017

Yongseok Choi

5

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Savitri Maddileti

7

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12 August 2017

Xiao D. Ji

6

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Victor E. Marquez

8

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T. Kendall Harden

9

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26 March 2024

Kenneth A. Jacobson

10

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publication date

1 November 2003

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12 August 2017

6 November 2003

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26 March 2024

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26 March 2024

https://europepmc.org/articles/PMC3408611

online access status

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Europe PubMed Central

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26 March 2024

https://europepmc.org/articles/PMC3408611?pdf=render

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26 March 2024

https://doi.org/10.1021/jm030127+

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26 March 2024

https://pubs.acs.org/doi/pdf/10.1021/jm030127%2B

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10.1021/JM030127+

https://api.crossref.org/works/10.1021/JM030127+

26 March 2024

Journal of Medicinal Chemistry

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Europe PubMed Central

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12 August 2017

46

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Europe PubMed Central

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12 August 2017

23

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Europe PubMed Central

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12 August 2017

4974-4987

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Activity of Novel Adenine Nucleotide Derivatives as Agonists and Antagonists at Recombinant Rat P2X Receptors

1 reference

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Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family

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Acyclic analogues of adenosine bisphosphates as P2Y receptor antagonists: phosphate substitution leads to multiple pathways of inhibition of platelet aggregation.

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Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist

1 reference

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Enantioselective synthesis of bicyclo[3.1.0]hexane carbocyclic nucleosides via a lipase-catalyzed asymmetric acetylation. Characterization of an unusual acetal byproduct

1 reference

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2-Chloro N(6)-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate is a selective high affinity P2Y(1) receptor antagonist

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ADP-evoked phospholipase C stimulation and adenylyl cyclase inhibition in glioma C6 cells occur through two distinct nucleotide receptors, P2Y(1) and P2Y(12).

1 reference

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Nucleotide-mediated relaxation in guinea-pig aorta: selective inhibition by MRS2179.

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P2 receptor-types involved in astrogliosis in vivo

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Identification of a novel human ADP receptor coupled to G(i)

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1 reference

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International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits

1 reference

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2 October 2017

Molecular pharmacology of P2Y-receptors

1 reference

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2 October 2017

A G protein-coupled receptor for UDP-glucose

1 reference

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2 October 2017

Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists.

1 reference

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2 October 2017

Identification of potent P2Y-purinoceptor agonists that are derivatives of adenosine 5'-monophosphate

1 reference

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2 October 2017

Cloning and tissue distribution of the human P2Y1 receptor

1 reference

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Identification of potent, selective P2Y-purinoceptor agonists: structure-activity relationships for 2-thioether derivatives of adenosine 5'-triphosphate

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Pharmacological Reviews

2

53

118

author name string

Khakh B. S.

publication date

2001

1 reference

10.1021/JM030127+

https://api.crossref.org/works/10.1021/JM030127+

26 March 2024

Journal of Biological Chemistry

4

276

41485

author name string

Communi D.

publication date

2001

1 reference

10.1021/JM030127+

https://api.crossref.org/works/10.1021/JM030127+

26 March 2024

Journal of Biological Chemistry

6

275

10771

author name string

Chambers J. K.

publication date

2000

1 reference

10.1021/JM030127+

https://api.crossref.org/works/10.1021/JM030127+

26 March 2024

Journal of Medicinal Chemistry

19

44

3108

author name string

Kim H. S.

publication date

2001

1 reference

10.1021/JM030127+

https://api.crossref.org/works/10.1021/JM030127+

26 March 2024

Journal of Medicinal Chemistry

23

42

3646

author name string

Fischer B.

publication date

1999

1 reference

10.1021/JM030127+

https://api.crossref.org/works/10.1021/JM030127+

26 March 2024

Journal of the American Chemical Society

35

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14916

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Wilds C. J.

publication date

2002

1 reference

10.1021/JM030127+

https://api.crossref.org/works/10.1021/JM030127+

26 March 2024

Canadian Journal of Chemistry

36

59

2611

author name string

Robins M. J.

publication date

1981

1 reference

10.1021/JM030127+

https://api.crossref.org/works/10.1021/JM030127+

26 March 2024

Journal of Medicinal Chemistry

45

45

5709

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Xu B.

publication date

2002

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10.1021/JM030127+

https://api.crossref.org/works/10.1021/JM030127+

26 March 2024

Organic Letters

46

3

599

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Lee K.

publication date

2001

1 reference

10.1021/JM030127+

https://api.crossref.org/works/10.1021/JM030127+

26 March 2024

Journal of Biological Chemistry

48

264

890

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Boyer J. L.

publication date

1989

1 reference

10.1021/JM030127+

https://api.crossref.org/works/10.1021/JM030127+

26 March 2024

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10.1021/JM030127+

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12 August 2017

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12 August 2017

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12 August 2017

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