The Continuing Evolution of HIV-1 Therapy: Identification and Development of Novel Antiretroviral Agents Targeting Viral and Cellular Targets (Q36104509)

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English	The Continuing Evolution of HIV-1 Therapy: Identification and Development of Novel Antiretroviral Agents Targeting Viral and Cellular Targets	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

The Continuing Evolution of HIV-1 Therapy: Identification and Development of Novel Antiretroviral Agents Targeting Viral and Cellular Targets (English)

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Europe PubMed Central

PMC publication ID

12 August 2017

anti-retroviral agent

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Robert W Buckheit

2

object named as

Robert W Buckheit

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Europe PubMed Central

PMC publication ID

12 August 2017

author name string

Tracy L Hartman

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Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

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based on heuristic

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publication date

10 July 2012

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Europe PubMed Central

PMC publication ID

12 August 2017

Molecular Biology International

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Europe PubMed Central

PMC publication ID

12 August 2017

2012

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Europe PubMed Central

PMC publication ID

12 August 2017

401965

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Europe PubMed Central

PMC publication ID

12 August 2017

copyright license

Creative Commons Attribution 3.0 Unported

10 July 2012

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April 2022 Public Data File from Crossref

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April 2022 Public Data File from Crossref

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HIV reservoirs and latency models.

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Modulation of HIV-1-host interaction: role of the Vpu accessory protein

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Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance.

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Cell-cell spread of human immunodeficiency virus type 1 overcomes tetherin/BST-2-mediated restriction in T cells

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Two-year safety and virologic efficacy of maraviroc in treatment-experienced patients with CCR5-tropic HIV-1 infection: 96-week combined analysis of MOTIVATE 1 and 2.

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Pharmacophore and structure-activity relationships of integrase inhibition within a dual inhibitor scaffold of HIV reverse transcriptase and integrase.

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Development of hexadecyloxypropyl tenofovir (CMX157) for treatment of infection caused by wild-type and nucleoside/nucleotide-resistant HIV.

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2 October 2017

Effects of intermittent IL-2 alone or with peri-cycle antiretroviral therapy in early HIV infection: the STALWART study

1 reference

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Inhibition of HIV-1 replication by a bis-thiadiazolbenzene-1,2-diamine that chelates zinc ions from retroviral nucleocapsid zinc fingers

1 reference

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Inhibition of human immunodeficiency virus type 1 by triciribine involves the accessory protein nef

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Structural Basis for the Role of the K65R Mutation in HIV-1 Reverse Transcriptase Polymerization, Excision Antagonism, and Tenofovir Resistance

1 reference

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2 October 2017

Human immunodeficiency virus type 1 protease-correlated cleavage site mutations enhance inhibitor resistance

1 reference

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Human immunodeficiency virus, restriction factors, and interferon

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Host cell factors in HIV replication: meta-analysis of genome-wide studies

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Angiotensin-(1-7) stimulates hematopoietic progenitor cells in vitro and in vivo

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2 October 2017

Cessation of HIV-1 transcription by inhibiting regulatory protein Rev-mediated RNA transport

1 reference

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2 October 2017

Cataloguing the HIV type 1 human protein interaction network

1 reference

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Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity

1 reference

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1 reference

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2 October 2017

Small-molecule inhibition of HIV-1 Vif.

1 reference

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2 October 2017

Anti-human immunodeficiency virus type 1 activities of antimicrobial peptides derived from human and bovine cathelicidins

1 reference

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Setting the stage: host invasion by HIV.

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Development of a comprehensive human immunodeficiency virus type 1 screening algorithm for discovery and preclinical testing of topical microbicides.

1 reference

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2 October 2017

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

1 reference

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2 October 2017

The naphthyridinone GSK364735 is a novel, potent human immunodeficiency virus type 1 integrase inhibitor and antiretroviral

1 reference

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2 October 2017

A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2

1 reference

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2 October 2017

Allosteric inhibition of the HIV-1 Rev/RRE interaction by a 3'-methylphosphonate modified antisense oligo-2'-O-methylribonucleotide

1 reference

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2 October 2017

The benzamide derivative N-[1-(7-tert-Butyl-1H-indol-3-ylmethyl)-2-(4-cyclopropanecarbonyl-3-methyl-piperazin-1-yl)-2-oxo-ethyl]-4-nitro-benzamide (SP-10) reduces HIV-1 infectivity in vitro by modifying actin dynamics

1 reference

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2 October 2017

HIV-1 Reverse Transcriptase Structure with RNase H Inhibitor Dihydroxy Benzoyl Naphthyl Hydrazone Bound at a Novel Site

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Validation overview of bio-analytical methods

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2 October 2017

Progress in targeting HIV-1 entry.

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2 October 2017

4-Phenylcoumarins as HIV transcription inhibitors.

1 reference

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2 October 2017

Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision

1 reference

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2 October 2017

Controlling HIV-1 Rev function

1 reference

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2 October 2017

Designing anti-AIDS drugs targeting the major mechanism of HIV-1 RT resistance to nucleoside analog drugs

1 reference

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2 October 2017

Inhibitors of HIV-1 gene expression and transcription

1 reference

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2 October 2017

Recommendations for the nonclinical development of topical microbicides for prevention of HIV transmission: an update

1 reference

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2 October 2017

Growing in silence: selected regions and countries with expanding HIV/AIDS epidemics

1 reference

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2 October 2017

APD: the Antimicrobial Peptide Database

1 reference

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2 October 2017

PA-457: A potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing

1 reference

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2 October 2017

DNA deamination mediates innate immunity to retroviral infection

1 reference

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2 October 2017

LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells

1 reference

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2 October 2017

Genetic selection of peptide inhibitors of human immunodeficiency virus type 1 Vpr.

1 reference

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2 October 2017

Myristoylation as a target for inhibiting HIV assembly: unsaturated fatty acids block viral budding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

2 October 2017

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

1 reference

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2 October 2017

Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes

1 reference

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2 October 2017

Human immunodeficiency virus type 1 uses lipid raft-colocalized CD4 and chemokine receptors for productive entry into CD4(+) T cells

1 reference

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2 October 2017

Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

1 reference

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2 October 2017

Cell-based fluorescence assay for human immunodeficiency virus type 1 protease activity

1 reference

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2 October 2017

Human immunodeficiency virus type 1 protease cleavage site mutations associated with protease inhibitor cross-resistance selected by indinavir, ritonavir, and/or saquinavir

1 reference

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2 October 2017

HIV-1 drug resistance in newly infected individuals

1 reference

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2 October 2017

Latent reservoirs of HIV: obstacles to the eradication of virus

1 reference

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2 October 2017

The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II

1 reference

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2 October 2017

Complementation of integrase function in HIV-1 virions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

2 October 2017

Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

1 reference

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2 October 2017

An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication

1 reference

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2 October 2017

Azodicarbonamide inhibits HIV-1 replication by targeting the nucleocapsid protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

2 October 2017

Inhibitors of human immunodeficiency virus type 1 zinc fingers prevent normal processing of gag precursors and result in the release of noninfectious virus particles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

2 October 2017

Viral resistance and the selection of antiretroviral combinations

1 reference

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2 October 2017

Recombining the structures of HIV integrase, RuvC and RNase H.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

2 October 2017

Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

2 October 2017

Phase I study of tricyclic nucleoside phosphate using a five-day continuous infusion schedule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

2 October 2017

Replication of human immunodeficiency virus 1 and Moloney murine leukemia virus is inhibited by different heteroatom-containing analogs of myristic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

2 October 2017

Inhibition of human immunodeficiency virus 1 protease in vitro: rational design of substrate analogue inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

2 October 2017

Myristoylation-dependent replication and assembly of human immunodeficiency virus 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

2 October 2017

HIV inhibitors targeted at the reverse transcriptase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

2 October 2017

Inhibition of HIV-1 ribonuclease H by a novel diketo acid, 4-[5-(benzoylamino)thien-2-yl]-2,4-dioxobutanoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

2 July 2018

Progress in the study of HIV-1 Vif and related inhibitors

1 reference

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23 September 2018

Efavirenz accelerates HIV-1 reverse transcriptase ribonuclease H cleavage, leading to diminished zidovudine excision

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

23 September 2018

Cell-based chemical genetic screen identifies damnacanthal as an inhibitor of HIV-1 Vpr induced cell death

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23 September 2018

Primary HIV drug resistance and efficacy of first-line antiretroviral therapy guided by resistance testing

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23 September 2018

High frequency of highly active antiretroviral therapy modifications in patients with acute or early human immunodeficiency virus infection

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

23 September 2018

Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

23 September 2018

Natural resistance-associated mutations to Enfuvirtide (T20) and polymorphisms in the gp41 region of different HIV-1 genetic forms from T20 naive patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

23 September 2018

Defining the toxicity profile of nevirapine and other antiretroviral drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

23 September 2018

Prostratin: activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

23 September 2018

Drug-resistant HIV-1: the virus strikes back

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

23 September 2018

Drug resistance and heterogeneous long-term virologic responses of human immunodeficiency virus type 1-infected subjects to zidovudine and didanosine combination therapy. The AIDS Clinical Trials Group 143 Virology Team

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3400388

23 September 2018

CYT107 enters Phase II clinical trial in HIV-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22848825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitive ELISA for the gp120 and gp160 surface glycoproteins of HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22848825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A multicenter, randomized, controlled trial of three preparations of low-dose oral alpha-interferon in HIV-infected patients with CD4+ counts between 50 and 350 cells/mm(3). Division of AIDS Treatment Research Initiative (DATRI) 022 Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/22848825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent developments in HIV protease inhibitor therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22848825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Design, synthesis and evaluation of novel 2H-1, 4-benzodiazepine-2-ones as inhibitors of HIV-1 transcription]

1 reference

https://pubmed.ncbi.nlm.nih.gov/22848825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design, asymmetric synthesis, and evaluation of pseudosymmetric sulfoximine inhibitors against HIV-1 protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22848825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New class of medications approved for advance HIV

1 reference

https://pubmed.ncbi.nlm.nih.gov/22848825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting RNA with small molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/22848825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical evaluation of a zinc finger inhibitor targeting lentivirus nucleocapsid protein in SIV-infected monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/22848825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2012/401965

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

0 references

Sitelinks

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