The role of proteolytic enzymes in cancer invasion and metastasis (Q36093846)

12 August 2017

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title

The role of proteolytic enzymes in cancer invasion and metastasis (English)

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12 August 2017

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neoplasm invasiveness

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1582084

11 October 2022

metastasis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1582084

11 October 2022

M. J. Duffy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1582084

11 October 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1582084

11 October 2022

publication date

1 May 1992

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Clinical & Experimental Metastasis

12 August 2017

published in

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12 August 2017

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12 August 2017

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12 August 2017

page(s)

145-155

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Autocrine growth stimulation of the MCF 7 breast cancer cells by the estrogen-regulated 52 K protein.

12 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF00132746

Correlation of collagenase secretion with metastatic-colonization potential in naturally occurring murine mammary tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00132746

Role for different cell proteinases in cancer invasion and cytolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00132746

Inhibitory properties of low molecular mass cysteine proteinase inhibitors from human sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00132746

Expression of human recombinant plasminogen activators enhances invasion and experimental metastasis of H-ras-transformed NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00132746

Antibodies to plasminogen activator inhibit human tumor metastasis

21 January 2018

1 reference

12 December 2020

Differential protease expression by cutaneous squamous and basal cell carcinomas

1 reference

12 December 2020

Tissue-type plasminogen activator in breast cancer: relationship with estradiol and progesterone receptors

1 reference

12 December 2020

Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture

1 reference

12 December 2020

Clinical and experimental studies on the biology of metastasis

1 reference

12 December 2020

Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase

1 reference

12 December 2020

Clinical relevance of the urokinase-type and tissue-type plasminogen activators and of their type 1 inhibitor in breast cancer

1 reference

12 December 2020

Cathepsin D: an independent prognostic factor for metastasis of breast cancer

1 reference

12 December 2020

Involvement of plasminogen activator production with tumor metastasis in a rat model

1 reference

12 December 2020

Relationship between secreted urokinase plasminogen activator activity and metastatic potential in murine B16 cells transfected with human urokinase sense and antisense genes

1 reference

12 December 2020

Differential release of active proteinase inhibitors by two rat mammary adenocarcinoma variants possessing different metastatic potentials.

1 reference

12 December 2020

Urokinase-plasminogen activator, a new and independent prognostic marker in breast cancer

1 reference

12 December 2020

Mr 92,000 gelatinase release correlates with the metastatic phenotype in transformed rat embryo cells

1 reference

12 December 2020

Localization in vivo of radio-iodinated anti-rat-fibrin antibodies and radio-iodinated rat fibrinogen in the Murphy rat lymphosarcoma and in other transplantable rat tumors

1 reference

12 December 2020

Tumor cell-platelet aggregation: induced by cathepsin B-like proteinase and inhibited by prostacyclin

1 reference

12 December 2020

Identification of cell surface cathepsin B-like activity on murine melanomas and fibrosarcomas: modulation by butanol extraction

1 reference

12 December 2020

Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinases

1 reference

12 December 2020

Heparanases and tumor metastasis

1 reference

12 December 2020

Urokinase-plasminogen activator, a marker for aggressive breast carcinomas. Preliminary report

1 reference

12 December 2020

Increased capillary endothelial cell protease activity in response to angiogenic stimuli in vitro

1 reference

12 December 2020

Inhibition of urokinase-type plasminogen activator by antibodies: the effect on dissemination of a human tumor in the nude mouse

1 reference

12 December 2020

Increased secretion, altered processing, and glycosylation of pro-cathepsin D in human mammary cancer cells

1 reference

12 December 2020

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase

1 reference

12 December 2020

Metalloproteinases and cancer invasion and metastasis

1 reference

12 December 2020

Relationship between cellular procoagulant activity and metastatic capacity of B16 mouse melanoma variants

1 reference

12 December 2020

Tissue-type plasminogen activator, a new prognostic marker in breast cancer

1 reference

12 December 2020

A novel TIMP-insensitive type IV collagen-degrading metalloproteinase from murine metastatic sarcoma cells

1 reference

12 December 2020

Cathepsin B: association with plasma membrane in metastatic tumors

1 reference

12 December 2020

Cathepsin B to cysteine proteinase inhibitor balance in metastatic cell subpopulations isolated from murine tumors

1 reference

12 December 2020

Invasion potential of human choriocarcinoma cell lines and the role of lytic enzymes

1 reference

12 December 2020

Mouse L cells expressing human prourokinase-type plasminogen activator: effects on extracellular matrix degradation and invasion

1 reference

12 December 2020

Immunohistochemical evidence of urokinase-type plasminogen activator in primary and metastatic tumors of pulmonary adenocarcinoma

1 reference

12 December 2020

Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA)

1 reference

12 December 2020

Tumor invasion through the human amniotic membrane: requirement for a proteinase cascade

1 reference

12 December 2020

Expression of collagenase-related metalloproteinase genes in human lung or head and neck tumours

1 reference

12 December 2020

Inhibition of tumor invasion of smooth muscle cell layers by recombinant human metalloproteinase inhibitor.

1 reference

12 December 2020

In vivo invasion of modified chorioallantoic membrane by tumor cells: the role of cell surface-bound urokinase

1 reference

12 December 2020

Human urokinase-type plasminogen activator stimulates chemotaxis of human neutrophils

1 reference

12 December 2020

Urokinase-type plasminogen activator antigen and early relapse in breast cancer

1 reference

12 December 2020

Urokinase plasminogen activator and prognosis in breast cancer

1 reference

12 December 2020

In vitro degradation of extracellular matrix with Mr 52,000 cathepsin D secreted by breast cancer cells

1 reference

12 December 2020

Expression of five cathepsins in murine melanomas of varying metastatic potential and normal tissues

1 reference

12 December 2020

Proliferation of a human epidermal tumor cell line stimulated by urokinase

1 reference

12 December 2020

Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a

1 reference

12 December 2020

Plasminogen activation and regulation of pericellular proteolysis

1 reference

12 December 2020

Matrix metalloproteinases and tissue inhibitor of metalloproteinases: a review of their role in tumorigenesis and tissue invasion

1 reference

12 December 2020

Modulation of metastatic potential by cell surface urokinase of murine melanoma cells

1 reference

12 December 2020

Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo

1 reference

12 December 2020

Laminin receptors, collagenase IV and prognosis in node-negative breast cancers

1 reference

12 December 2020

Extracellular cysteine proteinase and collagenase activities as a consequence of tumor-host interaction in the rabbit V2 carcinoma

1 reference

12 December 2020

Cathepsin D: a protease involved in breast cancer metastasis

1 reference

12 December 2020

Correlation of the production of plasminogen activator with tumor metastasis in B16 mouse melanoma cell lines

1 reference

12 December 2020

Cellular detachment by purified lysosomal cathepsin B

1 reference

12 December 2020

Plasminogen activators and cancer

1 reference

12 December 2020

Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells

1 reference

12 December 2020

Do proteases play a role in cancer invasion and metastasis?

1 reference

12 December 2020

Inhibition of cancer cell urokinase plasminogen activator by its specific inhibitor PAI-2 and subsequent effects on extracellular matrix degradation

1 reference

12 December 2020

Effects of tranexamic acid and urokinase on hematogenous metastases of Lewis lung carcinoma in mice

1 reference

12 December 2020

Structure and biological activity of basement membrane proteins

1 reference

12 December 2020

Modulation of type-IV collagenase activity and invasive behavior of metastatic human melanoma (A2058) cells in vitro by monoclonal antibodies to type-IV collagenase

1 reference

12 December 2020

Further studies on the activation of procollagenase, the latent precursor of bone collagenase. Effects of lysosomal cathepsin B, plasmin and kallikrein, and spontaneous activation

1 reference

12 December 2020

Prognostic significance of the estrogen-regulated protein, cathepsin D, in breast cancer. An immunohistochemical study

1 reference

12 December 2020

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1 reference

12 December 2020

Immunocytochemical localization of urokinase-type plasminogen activator in Lewis lung carcinoma

1 reference

12 December 2020

Biochemical methods for predicting metastatic ability of prostatic cancer utilizing the dunning R-3327 rat prostatic adenocarcinoma system as a model

1 reference

12 December 2020

Plasminogen activator inhibitor-type 1 in Lewis lung carcinoma

1 reference

12 December 2020

Association between high concentrations of Mr 52,000 cathepsin D and poor prognosis in primary human breast cancer

1 reference

12 December 2020

Inhibition by human recombinant tissue inhibitor of metalloproteinases of human amnion invasion and lung colonization by murine B16-F10 melanoma cells

1 reference

12 December 2020

Identification of latent procathepsins B and L in microsomal lumen: characterization of enzymatic activation and proteolytic processing in vitro

1 reference

12 December 2020

Collagenase Activity in Epidermoid Carcinoma of the Oral Cavity and Larynx

1 reference

12 December 2020

The role of urokinase-type plasminogen activator in aggressive tumor cell behavior

1 reference

12 December 2020

Stromelysin in tumor progression and metastasis

1 reference

12 December 2020

Cathepsin B-like proteinase as a marker for metastatic tumor cell variants

1 reference

12 December 2020

Proteolytic enzymes in tumor metastasis. I. Plasminogen activator in clones of Lewis lung carcinoma and T10 sarcoma.

1 reference

12 December 2020

Proteolytic degradation of extracellular matrix in tumor invasion

1 reference

12 December 2020

The glycosylation state of the precursors of the cathepsin B-like proteinase from human malignant ascitic fluid: possible implication in the secretory pathway of these proenzymes.

1 reference

12 December 2020

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes

1 reference

12 December 2020

Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency.

1 reference

12 December 2020

A fibrosarcoma model derived from mouse embryo cells: Growth properties and secretion of collagenase and metalloproteinase inhibitor (TIMP) by tumour cell lines

1 reference

12 December 2020

Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium

1 reference

12 December 2020

Production of collagenase and inhibitor (TIMP) by intracranial tumors and dura in vitro

1 reference

12 December 2020

A secreted glycoprotein induced by estrogen in human breast cancer cell lines

1 reference

12 December 2020

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

1 reference

12 December 2020

Partial purification and characterization of a neutral protease which cleaves type IV collagen

1 reference

12 December 2020

Effect of proteinase inhibitors on intracellular processing of cathepsin B, H and L in rat macrophages

1 reference

12 December 2020

Plasminogen-activator inhibitor type 1 is a potent natural inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cells

1 reference

12 December 2020

SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages

1 reference

12 December 2020

Cathepsin B and its endogenous inhibitors: the role in tumor malignancy

1 reference

12 December 2020

Effect of urokinase on growth and metastases of rabbit V2 carcinoma

1 reference

12 December 2020

Lysosomal cathepsin B: correlation with metastatic potential

1 reference

12 December 2020

Cathepsin D and prognosis in breast cancer

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00132746

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12 August 2017

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