Na(+) channel mutation that causes both Brugada and long-QT syndrome phenotypes: a simulation study of mechanism (Q36019333)

11 August 2017

Na(+) channel mutation that causes both Brugada and long-QT syndrome phenotypes: a simulation study of mechanism (English)

1 reference

11 August 2017

Colleen E Clancy

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11 August 2017

Yoram Rudy

series ordinal

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11 August 2017

language of work or name

English

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publication date

1 March 2002

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11 August 2017

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11 August 2017

105

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11 August 2017

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11 August 2017

1208-1213

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Novel arrhythmogenic mechanism revealed by a long-QT syndrome mutation in the cardiac Na(+) channel.

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

The Brugada syndrome: ionic basis and arrhythmia mechanisms

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Enhanced Na(+) channel intermediate inactivation in Brugada syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Arrhythmogenic mechanism of an LQT-3 mutation of the human heart Na(+) channel alpha-subunit: A computational analysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

A single Na(+) channel mutation causing both long-QT and Brugada syndromes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Pause induced early afterdepolarizations in the long QT syndrome: a simulation study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Ionic mechanisms responsible for the electrocardiographic phenotype of the Brugada syndrome are temperature dependent

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Multiple effects of KPQ deletion mutation on gating of human cardiac Na+ channels expressed in mammalian cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Characterization of human cardiac Na+ channel mutations in the congenital long QT syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Molecular mechanism for an inherited cardiac arrhythmia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Two components of the delayed rectifier K+ current in ventricular myocytes of the guinea pig type. Theoretical formulation and their role in repolarization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Multiple mechanisms of Na+ channel--linked long-QT syndrome

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1997279

Two distinct congenital arrhythmias evoked by a multidysfunctional Na(+) channel

23 September 2018

1 reference

12 December 2020

Role of the calcium-independent transient outward current I(to1) in shaping action potential morphology and duration

1 reference

12 December 2020

Cellular consequences of HERG mutations in the long QT syndrome: precursors to sudden cardiac death

1 reference

12 December 2020

Ionic bases for electrophysiological distinctions among epicardial, midmyocardial, and endocardial myocytes from the free wall of the canine left ventricle

1 reference

12 December 2020

Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia

1 reference

12 December 2020

Effects of IKr and IKs heterogeneity on action potential duration and its rate dependence: a simulation study

1 reference

12 December 2020

Identifiers

DOI

10.1161/HC1002.105183

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11 August 2017

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11 August 2017

PubMed publication ID

11889015

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