Multiple cholesterol recognition/interaction amino acid consensus (CRAC) motifs in cytosolic C tail of Slo1 subunit determine cholesterol sensitivity of Ca2+- and voltage-gated K+ (BK) channels (Q36016953)

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English	Multiple cholesterol recognition/interaction amino acid consensus (CRAC) motifs in cytosolic C tail of Slo1 subunit determine cholesterol sensitivity of Ca2+- and voltage-gated K+ (BK) channels	scientific article

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27 January 2020

Multiple cholesterol recognition/interaction amino acid consensus (CRAC) motifs in cytosolic C tail of Slo1 subunit determine cholesterol sensitivity of Ca2+- and voltage-gated K+ (BK) channels (English)

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27 January 2020

Aditya Kumar Singh

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27 January 2020

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Jacob McMillan

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27 January 2020

Anna N Bukiya

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27 January 2020

Brittany Burton

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27 January 2020

Abby L Parrill

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27 January 2020

Alex M Dopico

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27 January 2020

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3 April 2012

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27 January 2020

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Journal of Biological Chemistry

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27 January 2020

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27 January 2020

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27 January 2020

20509-20521

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27 January 2020

Open structure of the Ca2+ gating ring in the high-conductance Ca2+-activated K+ channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Identification of a Binding Motif in the S5 Helix That Confers Cholesterol Sensitivity to the TRPV1 Ion Channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Specificity of cholesterol and analogs to modulate BK channels points to direct sterol-channel protein interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

BK channel activation: structural and functional insights

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Cholesterol and ion channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Cholesterol and myelin biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Cholesterol effects on nicotinic acetylcholine receptor: cellular aspects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Cholesterol interaction with proteins that partition into membrane domains: an overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Cholesterol-protein interaction: methods and cholesterol reporter molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Identification of a C-terminus domain critical for the sensitivity of Kir2.1 to cholesterol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Kv11.1 (ERG1) K+ channels localize in cholesterol and sphingolipid enriched membranes and are modulated by membrane cholesterol

1 reference

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2 October 2017

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

1 reference

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An unexpected role for ion channels in brain tumor metastasis

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Lipid bilayer-mediated regulation of ion channel function by amphiphilic drugs

1 reference

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The second transmembrane domain of the large conductance, voltage- and calcium-gated potassium channel beta(1) subunit is a lithocholate sensor

1 reference

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2 October 2017

High-conductance potassium channels of the SLO family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Large conductance Ca2+-activated K+ (BK) channel: activation by Ca2+ and voltage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Cholesterol and the interaction of proteins with membrane domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

The Amber biomolecular simulation programs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Heme is a carbon monoxide receptor for large-conductance Ca2+-activated K+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

The BKCa channel's Ca2+-binding sites, multiple sites, multiple ions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

What's so special about cholesterol?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Identification of a conserved domain of the HIV-1 transmembrane protein gp41 which interacts with cholesteryl groups

1 reference

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2 October 2017

Calcium activation of BK(Ca) potassium channels lacking the calcium bowl and RCK domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

The cytoplasmic tail of large conductance, voltage- and Ca2+-activated K+ (MaxiK) channel is necessary for its cell surface expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Cholesterol binding at the cholesterol recognition/ interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide

1 reference

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2 October 2017

Has nature designed the cholesterol side chain for optimal interaction with phospholipids?

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

2 October 2017

Smooth muscle cholesterol enables BK β1 subunit-mediated channel inhibition and subsequent vasoconstriction evoked by alcohol

1 reference

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Cholesterol depletion alters coronary artery myocyte Ca(2+) signalling in a stimulus-specific manner

1 reference

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Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase

1 reference

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11 July 2018

Variations of membrane cholesterol alter the kinetics of Ca2(+)-dependent K+ channels and membrane fluidity in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

11 July 2018

Lipid stress at play: mechanosensitivity of voltage-gated channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

23 September 2018

Identification of cholesterol recognition amino acid consensus (CRAC) motif in G-protein coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370236

23 September 2018

Cholesterol regulates the endoplasmic reticulum exit of the major membrane protein P0 required for peripheral myelin compaction.

1 reference

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Cytolethal distending toxin-induced cell cycle arrest of lymphocytes is dependent upon recognition and binding to cholesterol

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Sigma-1 receptors bind cholesterol and remodel lipid rafts in breast cancer cell lines

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23 September 2018

Identification of a conserved domain of the HIV-1 transmembrane protein gp41 which interacts with cholesteryl groups

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22474334

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inferred from PubMed ID database lookup

Effect of hypercholesterolemia on Ca(2+)-dependent K(+) channel-mediated vasodilatation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22474334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in membrane cholesterol of pituitary tumor (GH3) cells regulate the activity of large-conductance Ca2+-activated K+ channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/22474334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis for lipid modulation of nicotinic acetylcholine receptor function

1 reference

https://pubmed.ncbi.nlm.nih.gov/22474334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1074/JBC.M112.356261

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22474334%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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27 January 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22474334%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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