Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer's disease (Q36001449)

11 August 2017

Critical role of soluble amyloid-β for early hippocampal hyperactivity in a mouse model of Alzheimer's disease (English)

1 reference

11 August 2017

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Bert Sakmann

1 reference

11 August 2017

Marc Aurel Busche

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Arthur Konnerth

1 reference

11 August 2017

Matthias Staufenbiel

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11 August 2017

Xiaowei Chen

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11 August 2017

Horst A Henning

series ordinal

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11 August 2017

Julia Reichwald

series ordinal

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11 August 2017

language of work or name

English

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publication date

16 May 2012

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Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

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11 August 2017

109

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11 August 2017

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11 August 2017

8740-8745

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describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3365221/fullTextXML

inferred from PubMed Central ID database lookup

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Functional imaging of hippocampal place cells at cellular resolution during virtual navigation

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NMDA-mediated Ca(2+) influx drives aberrant ryanodine receptor activation in dendrites of young Alzheimer's disease mice

2 October 2017

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How do Soluble Oligomers of Amyloid beta-protein Impair Hippocampal Synaptic Plasticity?

2 October 2017

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The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.

2 October 2017

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Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

2 October 2017

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Sparsification of neuronal activity in the visual cortex at eye-opening

2 October 2017

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Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

2 October 2017

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Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

2 October 2017

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Soluble amyloid-beta peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo.

2 October 2017

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Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

2 October 2017

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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

2 October 2017

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Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease

2 October 2017

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A specific amyloid-beta protein assembly in the brain impairs memory

2 October 2017

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Functional activation imaging in aging and dementia

2 October 2017

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Imaging input and output of neocortical networks in vivo

2 October 2017

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Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD

2 October 2017

1 reference

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Regulation of NMDA receptor trafficking by amyloid-beta

2 October 2017

1 reference

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Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo

2 October 2017

1 reference

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Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

2 October 2017

1 reference

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Pathways towards and away from Alzheimer's disease

2 October 2017

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In vivo two-photon calcium imaging of neuronal networks

2 October 2017

1 reference

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Video-rate confocal microscopy

2 October 2017

1 reference

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Alzheimer's disease is a synaptic failure

2 October 2017

1 reference

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

2 October 2017

1 reference

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High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

2 October 2017

1 reference

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Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

2 October 2017

1 reference

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Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

2 October 2017

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2 October 2017

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Alzheimer's disease: cell-specific pathology isolates the hippocampal formation

2 October 2017

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The medial temporal lobe memory system

2 October 2017

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A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo.

2 October 2017

1 reference

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Amyloid beta oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors.

23 September 2018

1 reference

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Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease

23 September 2018

1 reference

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Dynamics of Abeta turnover and deposition in different beta-amyloid precursor protein transgenic mouse models following gamma-secretase inhibition

23 September 2018

1 reference

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Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks

23 September 2018

1 reference

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Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365221

Targeted bulk-loading of fluorescent indicators for two-photon brain imaging in vivo

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365221

Acute gamma-secretase inhibition improves contextual fear conditioning in the Tg2576 mouse model of Alzheimer's disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365221

High-resolution in vivo imaging of hippocampal dendrites and spines.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365221

Studies of Abeta pharmacodynamics in the brain, cerebrospinal fluid, and plasma in young (plaque-free) Tg2576 mice using the gamma-secretase inhibitor N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365221

Electrophysiology of hippocampal neurons. I. Sequential invasion and synaptic organization

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365221

Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365221

The Ca2+ influx induced by beta-amyloid peptide 25-35 in cultured hippocampal neurons results from network excitation

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22592800

12 December 2020

inferred from PubMed ID database lookup

Initiation and propagation of neurodegeneration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22592800

12 December 2020

inferred from PubMed ID database lookup

Targeted patch-clamp recordings and single-cell electroporation of unlabeled neurons in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22592800

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1206171109

1 reference

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

22592800

1 reference