A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin (Q36007054)

11 August 2017

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin (English)

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11 August 2017

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Kwok WW

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11 August 2017

Alleva DG

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11 August 2017

Crowe PD

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11 August 2017

Jin L

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11 August 2017

Ling N

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11 August 2017

Gottschalk M

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11 August 2017

Conlon PJ

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11 August 2017

Gottlieb PA

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11 August 2017

Putnam AL

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11 August 2017

Gaur A

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11 August 2017

language of work or name

English

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publication date

1 January 2001

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Journal of Clinical Investigation

11 August 2017

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11 August 2017

107

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11 August 2017

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11 August 2017

173-180

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Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

11 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

T cell autoreactivity to proinsulin epitopes in diabetic patients and healthy subjects

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

Regulatory Th2-type T cell lines against insulin and GAD peptides derived from orally- and nasally-treated NOD mice suppress diabetes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

Enzyme-linked immunosorbent assay spot detection of interferon-gamma and interleukin 5-producing cells as a predictive marker for renal allograft failure

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

Biochemical characterization of the human diabetes-associated HLA-DQ8 allelic product: similarity to the major histocompatibility complex class II I-A(g)7 protein of non-obese diabetic mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

Cellular immune response to diverse islet cell antigens in IDDM.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcription

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

ICA512 Autoantibody Radioassay

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

T-Cell Subsets: Who does the polarizing?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

Comparison of a novel micro-assay for insulin autoantibodies with the conventional radiobinding assay

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

Correlates of insulin autoantibodies with beta cell function at the time of diagnosis of diabetes mellitus

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

Autoimmune diabetes: the role of T cells, MHC molecules and autoantigens

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

HLA-DQ polymorphisms are highly selective for peptide binding interactions

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=198872

T-cell response to proinsulin and insulin in type 1 and pretype 1 diabetes

23 September 2018

1 reference

12 December 2020

Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives

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12 December 2020

The pathogenesis of insulin-dependent diabetes mellitus

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12 December 2020

Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells

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12 December 2020

Cellular immune responses against proinsulin: no evidence for enhanced reactivity in individuals with IDDM

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12 December 2020

A new look at MHC and autoimmune disease

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12 December 2020

Radioimmunoassays for glutamic acid decarboxylase (GAD65) and GAD65 autoantibodies using 35S or 3H recombinant human ligands

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12 December 2020

HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent-onset insulin-dependent diabetes mellitus

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12 December 2020

Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies

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12 December 2020

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice

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12 December 2020

Altered immune response to insulin in newly diagnosed compared to insulin-treated diabetic patients and healthy control subjects

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12 December 2020

High T cell responses to the glutamic acid decarboxylase (GAD) isoform 67 reflect a hyperimmune state that precedes the onset of insulin-dependent diabetes

1 reference

12 December 2020

Autoimmune responses to the beta cell autoantigen, insulin, and the INS VNTR-IDDM2 locus

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12 December 2020

Direct detection of PCR products for HLA class II typing

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12 December 2020

Identifiers

DOI

10.1172/JCI8525

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11 August 2017

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11 August 2017

PubMed publication ID

11160133

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