Prion protein repeat expansion results in increased aggregation and reveals phenotypic variability. (Q35950108)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17548473%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Prion protein repeat expansion results in increased aggregation and reveals phenotypic variability (English)

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31 December 2019

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31 December 2019

Elizabeth M H Tank

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31 December 2019

Amar A Desai

series ordinal

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31 December 2019

Heather L True

series ordinal

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31 December 2019

language of work or name

English

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publication date

4 June 2007

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Molecular and Cellular Biology

31 December 2019

published in

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31 December 2019

volume

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31 December 2019

issue

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31 December 2019

page(s)

5445-5455

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Copper and the prion protein: methods, structures, function, and disease

31 December 2019

cites work

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An engineered nonsense URA3 allele provides a versatile system to detect the presence, absence and appearance of the [PSI+] prion in Saccharomyces cerevisiae

2 October 2017

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Octapeptide repeat insertions increase the rate of protease-resistant prion protein formation

2 October 2017

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The battle of the fold: chaperones take on prions

2 October 2017

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Structural insights into a yeast prion illuminate nucleation and strain diversity

2 October 2017

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2 October 2017

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Yeast [PSI+] Prion Aggregates Are Formed by Small Sup35 Polymers Fragmented by Hsp104

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Yeast prion protein derivative defective in aggregate shearing and production of new 'seeds'

2 October 2017

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Strains of [PSI(+)] are distinguished by their efficiencies of prion-mediated conformational conversion

2 October 2017

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Prions affect the appearance of other prions: the story of [PIN(+)].

2 October 2017

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Oligopeptide repeats in the yeast protein Sup35p stabilize intermolecular prion interactions

2 October 2017

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Prion diseases of humans and animals: their causes and molecular basis

2 October 2017

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Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation

2 October 2017

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Dependence and independence of [PSI(+)] and [PIN(+)]: a two-prion system in yeast?

2 October 2017

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2 October 2017

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Overexpression of the SUP45 gene encoding a Sup35p-binding protein inhibits the induction of the de novo appearance of the [PSI+] prion

2 October 2017

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Support for the prion hypothesis for inheritance of a phenotypic trait in yeast

2 October 2017

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Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells

2 October 2017

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Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]

2 October 2017

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Yeast vectors for the controlled expression of heterologous proteins in different genetic backgrounds

2 October 2017

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Mechanism of cross-species prion transmission: an infectious conformation compatible with two highly divergent yeast prion proteins

2 October 2017

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Octapeptide repeat insertions in the prion protein gene and early onset dementia

27 July 2018

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Conformational variations in an infectious protein determine prion strain differences

27 July 2018

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A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion

27 July 2018

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27 July 2018

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27 July 2018

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The SUP35 omnipotent suppressor gene is involved in the maintenance of the non-Mendelian determinant [psi+] in the yeast Saccharomyces cerevisiae.

27 July 2018

1 reference

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Non-genetic propagation of strain-specific properties of scrapie prion protein.

27 July 2018

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Identification of two biologically distinct strains of transmissible mink encephalopathy in hamsters

27 July 2018

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Distinct glycoform ratios of protease resistant prion protein associated with PRNP point mutations.

27 July 2018

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Prion variant maintained only at high levels of the Hsp104 disaggregase

24 September 2018

1 reference

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Transgenic mice expressing bovine PrP with a four extra repeat octapeptide insert mutation show a spontaneous, non-transmissible, neurodegenerative disease and an expedited course of BSE infection.

24 September 2018

1 reference

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Specificity of prion assembly in vivo. [PSI+] and [PIN+] form separate structures in yeast

24 September 2018

1 reference

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Protein-only transmission of three yeast prion strains

24 September 2018

1 reference

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Phenotypic variability in the brains of a family with a prion disease characterized by a 144-base pair insertion in the prion protein gene

24 September 2018

1 reference

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Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI(+)] prion.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952097

Local structural plasticity of the prion protein. Analysis of NMR relaxation dynamics

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952097

Neurological illness in transgenic mice expressing a prion protein with an insertional mutation.

24 September 2018

1 reference

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Experimental transmission of Creutzfeldt-Jakob disease and related diseases to rodents

24 September 2018

1 reference

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[Psi(+)] prion generation in yeast: characterization of the 'strain' difference

24 September 2018

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12 December 2020

The role of conformational flexibility in prion propagation and maintenance for Sup35p

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12 December 2020

Allelic origin of the abnormal prion protein isoform in familial prion diseases

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12 December 2020

Oligopeptide-repeat expansions modulate ‘protein-only’ inheritance in yeast

1 reference

12 December 2020

Prion proteins with insertion mutations have altered N-terminal conformation and increased ligand binding activity and are more susceptible to oxidative attack

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12 December 2020

Creating a protein-based element of inheritance

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12 December 2020

Identifiers

DOI

10.1128/MCB.02127-06

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17548473%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

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31 December 2019

PubMed publication ID

17548473

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17548473%20AND%20SRC:MED&resulttype=core&format=json