Molecular dioxygen enters the active site of 12/15-lipoxygenase via dynamic oxygen access channels (Q35941372)

11 August 2017

Molecular dioxygen enters the active site of 12/15-lipoxygenase via dynamic oxygen access channels (English)

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11 August 2017

Hermann-Georg Holzhütter

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object named as

Hermann-Georg Holzhütter

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11 August 2017

Hartmut Kuhn

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11 August 2017

Jan Saam

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11 August 2017

Igor Ivanov

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11 August 2017

Matthias Walther

series ordinal

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11 August 2017

language of work or name

English

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publication date

3 August 2007

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Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

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11 August 2017

104

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11 August 2017

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11 August 2017

13319-13324

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Control of oxygenation in lipoxygenase and cyclooxygenase catalysis

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Imaging the migration pathways for O2, CO, NO, and Xe inside myoglobin

2 October 2017

1 reference

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Inflammation and immune regulation by 12/15-lipoxygenases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Structural biology of mammalian lipoxygenases: enzymatic consequences of targeted alterations of the protein structure.

2 October 2017

1 reference

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Sub-atomic resolution crystal structure of cholesterol oxidase: what atomic resolution crystallography reveals about enzyme mechanism and the role of the FAD cofactor in redox activity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

The lipoxygenase pathway.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Prostaglandins and leukotrienes: advances in eicosanoid biology

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Oxygen access to the active site of cholesterol oxidase through a narrow channel is gated by an Arg-Glu pair

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Structural dynamics of ligand diffusion in the protein matrix: A study on a new myoglobin mutant Y(B10) Q(E7) R(E10)

2 October 2017

1 reference

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The structure of mammalian 15-lipoxygenase reveals similarity to the lipases and the determinants of substrate specificity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

VMD: visual molecular dynamics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

The three-dimensional structure of an arachidonic acid 15-lipoxygenase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

The structure and function of lipoxygenase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Cavities in proteins: structure of a metmyoglobin-xenon complex solved to 1.9 A.

2 October 2017

1 reference

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The role of lipoxygenase-isoforms in atherogenesis

2 October 2017

1 reference

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Dual role of oxygen during lipoxygenase reactions

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Kinetic Studies of Oxygen Reactivity in Soybean Lipoxygenase-1

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Steric control of oxygenation regiochemistry in soybean lipoxygenase-1.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Defining the arachidonic acid binding site of human 15-lipoxygenase. Molecular modeling and mutagenesis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

Penetration of dioxygen into proteins studied by quenching of phosphorescence and fluorescence

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1948941

All-atom empirical potential for molecular modeling and dynamics studies of proteins

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0702401104

A function for lipoxygenase in programmed organelle degradation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0702401104

Oxygen-linked equilibrium CuB-CO species in cytochrome ba3 oxidase from thermus thermophilus. Implications for an oxygen channel ar the CuB site

21 January 2018

1 reference

12 December 2020

C-11 H-abstraction from linoieic acid, the rate-limiting step in lipoxygenase catalysis

1 reference

12 December 2020

Channelling of dioxygen into the respiratory enzyme

1 reference

12 December 2020

Oxygen and proton pathways in cytochrome c oxidase

1 reference

12 December 2020

Copper amine oxidase from Hansenula polymorpha: the crystal structure determined at 2.4 A resolution reveals the active conformation

1 reference

12 December 2020

Affinities of various mammalian arachidonate lipoxygenases and cyclooxygenases for molecular oxygen as substrate

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0702401104

1 reference

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

17675410

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