Correlation of molecular and functional effects of mutations in cardiac troponin T linked to familial hypertrophic cardiomyopathy: an integrative in silico/in vitro approach (Q35922629)

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scientific article published on 13 February 2012

Language	Label	Description	Also known as
English	Correlation of molecular and functional effects of mutations in cardiac troponin T linked to familial hypertrophic cardiomyopathy: an integrative in silico/in vitro approach	scientific article published on 13 February 2012

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Correlation of molecular and functional effects of mutations in cardiac troponin T linked to familial hypertrophic cardiomyopathy: an integrative in silico/in vitro approach (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

hypertrophic cardiomyopathy

1 reference

based on heuristic

inferred from title

familial hypertrophic cardiomyopathy

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Edward P Manning

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Pia J Guinto

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Jil C Tardiff

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

0 references

publication date

13 February 2012

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

18

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

14515-14523

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

CHARMM: the biomolecular simulation program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Isoform diversity, regulation, and functional adaptation of troponin and calponin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

A novel mutant cardiac troponin C disrupts molecular motions critical for calcium binding affinity and cardiomyocyte contractility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Regulatory proteins alter nucleotide binding to acto-myosin of sliding filaments in motility assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Identification of a functionally critical protein kinase C phosphorylation residue of cardiac troponin T

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Evolutionarily conserved networks of residues mediate allosteric communication in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

The troponin tail domain promotes a conformational state of the thin filament that suppresses myosin activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Disease-causing mutations in cardiac troponin T: identification of a critical tropomyosin-binding region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Ca(2+) activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Regulation of contraction in striated muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Regulation of force and unloaded sliding speed in single thin filaments: effects of regulatory proteins and calcium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

The N-terminal region of troponin T is essential for the maximal activation of rat cardiac myofilaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Calcium regulation of skeletal muscle thin filament motility in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Thin filament-mediated regulation of cardiac contraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Calcium regulation of thin filament movement in an in vitro motility assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

VMD: visual molecular dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

2 October 2017

Roles for the troponin tail domain in thin filament assembly and regulation. A deletional study of cardiac troponin T.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340284

27 July 2018

Computational Characterization of Mutations in Cardiac Troponin T Known to Cause Familial Hypertrophic Cardiomyopathy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.257436

21 January 2018

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.257436

21 January 2018

The packing of α-helices: simple coiled-coils

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.257436

21 January 2018

Increase in tension-dependent ATP consumption induced by cardiac troponin T mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.257436

21 January 2018

Different effects of cardiac versus skeletal muscle regulatory proteins on in vitro measures of actin filament speed and force

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.257436

21 January 2018

The shape and flexibility of tropomyosin coiled coils: implications for actin filament assembly and regulation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.257436

21 January 2018

Long-range dynamic effects of point mutations propagate through side chains in the serine protease inhibitor eglin c.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.257436

21 January 2018

Familial hypertrophic cardiomyopathy mutations from different functional regions of troponin T result in different effects on the pH and Ca2+ sensitivity of cardiac muscle contraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22334656

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folding and function of the troponin tail domain. Effects of cardiomyopathic troponin T mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/22334656

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.257436

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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