Subcellular localization of talin is regulated by inter-domain interactions (Q35922268)

11 August 2017

Subcellular localization of talin is regulated by inter-domain interactions (English)

1 reference

11 August 2017

Asoka Banno

1 reference

11 August 2017

Benjamin T Goult

1 reference

11 August 2017

HoSup Lee

1 reference

11 August 2017

Neil Bate

1 reference

11 August 2017

David R Critchley

1 reference

11 August 2017

Mark H Ginsberg

1 reference

11 August 2017

language of work or name

English

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publication date

18 February 2012

1 reference

Journal of Biological Chemistry

11 August 2017

1 reference

11 August 2017

287

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11 August 2017

1 reference

11 August 2017

13799-13812

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Nanoscale architecture of integrin-based cell adhesions

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Recreation of the terminal events in physiological integrin activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Biochemical and structural properties of the integrin-associated cytoskeletal protein talin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

The Structure of an Interdomain Complex That Regulates Talin Activity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Stretching single talin rod molecules activates vinculin binding

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Mechanisms that regulate adaptor binding to beta-integrin cytoplasmic tails

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin alphaIIbbeta3

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

The structure of the C-terminal actin-binding domain of talin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Talin is required for integrin-mediated platelet function in hemostasis and thrombosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Functional atlas of the integrin adhesome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Platelet integrin alpha(IIb)beta(3): activation mechanisms

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Structural basis of integrin activation by talin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

The structure and regulation of vinculin.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Talin phosphorylation sites mapped by mass spectrometry

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

The CCPN data model for NMR spectroscopy: development of a software pipeline

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Calpain-mediated proteolysis of talin regulates adhesion dynamics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Structural determinants of integrin recognition by talin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Integrins: bidirectional, allosteric signaling machines

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

The phosphotyrosine binding-like domain of talin activates integrins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

ERM-Merlin and EBP50 protein families in plasma membrane organization and function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

1H, 13C and 15N chemical shift referencing in biomolecular NMR

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Regulation of integrin affinity states through an NPXY motif in the beta subunit cytoplasmic domain.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Direct evidence for the interaction of platelet surface membrane proteins GPIIb and III with cytoskeletal components: protein crosslinking studies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Activation-dependent redistribution of the adhesion plaque protein, talin, in intact human platelets

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Sequence and domain structure of talin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Structural basis for the autoinhibition of talin in regulating integrin activation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Talin is essential for integrin function in Drosophila

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340173

Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.

11 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.341214

Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.341214

The activity of the vinculin binding sites in talin is influenced by the stability of the helical bundles that make up the talin rod.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.341214

The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.341214

Vinculin activates inside-out signaling of integrin αIIbβ3 in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.341214

Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.341214

Structural basis for vinculin activation at sites of cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.341214

Characterization of an Actin-binding Site within the Talin FERM Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.341214

Induction of the fibrinogen receptor on human platelets by intracellular mediators

21 January 2018

1 reference

12 December 2020

Modulation of the affinity of integrin alpha IIb beta 3 (GPIIb-IIIa) by the cytoplasmic domain of alpha IIb

1 reference

12 December 2020

Talin distribution and phosphorylation in thrombin-activated platelets

1 reference

12 December 2020

Role of vinculin in regulating focal adhesion turnover

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M112.341214

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

22351767

1 reference