Microfluidic gradients reveal enhanced neurite outgrowth but impaired guidance within 3D matrices with high integrin ligand densities (Q35927869)

11 August 2017

Microfluidic gradients reveal enhanced neurite outgrowth but impaired guidance within 3D matrices with high integrin ligand densities (English)

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11 August 2017

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Nicole H Romano

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Kyle J Lampe

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11 August 2017

Hui Xu

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11 August 2017

Meghaan M Ferreira

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11 August 2017

Sarah C Heilshorn

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11 August 2017

14 October 2014

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11 August 2017

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11 August 2017

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11 August 2017

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11 August 2017

722-730

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describes a project that uses

11 August 2017

1 reference

10 June 2022

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&rettype=xml&id=4528974

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4528974/fullTextXML

inferred from PubMed Central ID database lookup

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Advances in peripheral nerve regeneration

2 October 2017

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Investigating axonal guidance with microdevice-based approaches.

2 October 2017

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2 October 2017

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2 October 2017

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Three-dimensional photolithographic micropatterning: a novel tool to probe the complexities of cell migration

2 October 2017

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Tetrakis(hydroxymethyl) phosphonium chloride as a covalent cross-linking agent for cell encapsulation within protein-based hydrogels

2 October 2017

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Multifunctional materials through modular protein engineering

2 October 2017

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Hydrogel design for supporting neurite outgrowth and promoting gene delivery to maximize neurite extension

2 October 2017

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A high-throughput microfluidic assay to study neurite response to growth factor gradients

2 October 2017

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A neuron-benign microfluidic gradient generator for studying the response of mammalian neurons towards axon guidance factors

2 October 2017

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The use of immobilized neurotrophins to support neuron survival and guide nerve fiber growth in compartmentalized chambers

2 October 2017

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Axon guidance by growth-rate modulation.

2 October 2017

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Current applications and future perspectives of artificial nerve conduits.

2 October 2017

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Bayesian model predicts the response of axons to molecular gradients

2 October 2017

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Tissue-engineered platforms of axon guidance

2 October 2017

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2 October 2017

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Differences between the effect of anisotropic and isotropic laminin and nerve growth factor presenting scaffolds on nerve regeneration across long peripheral nerve gaps

2 October 2017

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Glial inhibition of CNS axon regeneration

2 October 2017

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Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis

2 October 2017

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Peripheral nerve regeneration: an opinion on channels, scaffolds and anisotropy

2 October 2017

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Computational model for cell migration in three-dimensional matrices

2 October 2017

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Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering.

2 October 2017

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Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

2 October 2017

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Characterization of the turning response of dorsal root neurites toward nerve growth factor

2 October 2017

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Properties of the beta nerve growth factor receptor of avian dorsal root ganglia

2 October 2017

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The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor

2 October 2017

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Design of three-dimensional engineered protein hydrogels for tailored control of neurite growth

2 October 2017

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Neurotrophins and extracellular matrix molecules modulate sensory axon outgrowth

11 July 2018

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The relationships between interphase Schwann cells and axons before myelination: A quantitative electron microscopic study

11 July 2018

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Spatial gradients of chemotropic factors from immobilized patterns to guide axonal growth and regeneration

11 July 2018

1 reference

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Multi-molecular gradients of permissive and inhibitory cues direct neurite outgrowth

21 January 2018

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The effects of gradients of nerve growth factor immobilized PCLA scaffolds on neurite outgrowth in vitro and peripheral nerve regeneration in rats.

21 January 2018

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Matrix density mediates polarization and lumen formation of endothelial sprouts in VEGF gradients.

21 January 2018

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Investigating the synergistic effect of combined neurotrophic factor concentration gradients to guide axonal growth

21 January 2018

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A dual compartment diffusion chamber for studying axonal chemotaxis in 3D collagen

21 January 2018

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A microfluidics-based turning assay reveals complex growth cone responses to integrated gradients of substrate-bound ECM molecules and diffusible guidance cues

21 January 2018

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Immobilized concentration gradients of nerve growth factor guide neurite outgrowth.

21 January 2018

1 reference

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N-cadherin mediates axon-aligned process growth and cell-cell interaction in rat Schwann cells.

24 September 2018

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Generating different profiles of gradient concentrations inside a gel-filled chamber: design and simulation

24 September 2018

1 reference

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A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradients

21 January 2018

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Three-dimensional migration of neurites is mediated by adhesion site density and affinity

21 January 2018

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12 December 2020

DRG axon elongation and growth cone collapse rate induced by Sema3A are differently dependent on NGF concentration

1 reference

12 December 2020

Chemotactic response of nerve fiber elongation to nerve growth factor

1 reference

12 December 2020

The trkA receptor mediates growth cone turning toward a localized source of nerve growth factor

1 reference

12 December 2020

A laminin and nerve growth factor-laden three-dimensional scaffold for enhanced neurite extension

1 reference

12 December 2020

Defining the concentration gradient of nerve growth factor for guided neurite outgrowth

1 reference

12 December 2020

Identifiers

DOI

10.1002/SMLL.201401574

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

25315156

1 reference