The nuclear targeting and nuclear retention properties of a human DNA repair protein O6-methylguanine-DNA methyltransferase are both required for its nuclear localization: the possible implications (Q35905964)

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scientific article published in August 1996

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English	The nuclear targeting and nuclear retention properties of a human DNA repair protein O6-methylguanine-DNA methyltransferase are both required for its nuclear localization: the possible implications	scientific article published in August 1996

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scholarly article

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16 October 2019

The nuclear targeting and nuclear retention properties of a human DNA repair protein O6-methylguanine-DNA methyltransferase are both required for its nuclear localization: the possible implications (English)

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Europe PubMed Central

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16 October 2019

author name string

Lim A

1

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16 October 2019

Li BF

2

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16 October 2019

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1 August 1996

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16 October 2019

The EMBO Journal

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16 October 2019

15

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16 October 2019

15

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16 October 2019

4050-4060

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16 October 2019

Factors influencing the repair of the mutagenic lesion O6-methylguanine in DNA by human O6-methylguanine-DNA methyltransferase.

1 reference

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11 July 2018

Kinetic and DNA-binding properties of recombinant human O6-methylguanine-DNA methyltransferase

1 reference

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11 July 2018

Artificial control of nuclear translocation of DNA repair methyltransferase.

1 reference

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Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus

1 reference

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11 July 2018

Isolation of a protein that is essential for the first step of nuclear protein import

1 reference

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11 July 2018

Nuclear export signals and the fast track to the cytoplasm

1 reference

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11 July 2018

Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins

1 reference

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11 July 2018

A short amino acid sequence able to specify nuclear location

1 reference

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11 July 2018

The role of O6-methylguanine-DNA methyltransferase in cell survival, mutagenesis and carcinogenesis

1 reference

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11 July 2018

Protein import into the cell nucleus

1 reference

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Regulation and expression of the adaptive response to alkylating agents

1 reference

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Effect of basic and nonbasic amino acid substitutions on transport induced by simian virus 40 T-antigen synthetic peptide nuclear transport signals

1 reference

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Molecular analysis of O6-substituted guanine-induced mutagenesis of ras oncogenes

1 reference

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11 July 2018

Increase in nitrosourea resistance in mammalian cells by retrovirally mediated gene transfer of bacterial O6-alkylguanine-DNA alkyltransferase

1 reference

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11 July 2018

Isolation and structural characterization of a cDNA clone encoding the human DNA repair protein for O6-alkylguanine

1 reference

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11 July 2018

Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors

1 reference

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11 July 2018

A sensitive method for the determination of protein-DNA binding specificities

1 reference

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11 July 2018

Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents

1 reference

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11 July 2018

Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection

1 reference

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11 July 2018

Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452125

11 July 2018

How proteins enter the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452125

11 July 2018

Associations between distinct pre-mRNA splicing components and the cell nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452125

11 July 2018

Specific amino acid sequences required for O6-methylguanine-DNA methyltransferase activity: analyses of three residues at or near the methyl acceptor site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452125

11 July 2018

Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-kappa B subunit

1 reference

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11 July 2018

Immunohistological examination of the inter- and intracellular distribution of O6-alkylguanine DNA-alkyltransferase in human liver and melanoma

1 reference

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11 July 2018

Intracellular localization of human DNA repair enzyme methylguanine-DNA methyltransferase by antibodies and its importance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452125

11 July 2018

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

1 reference

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Structure and function of simian virus 40 large tumor antigen

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DNA sequencing with chain-terminating inhibitors

1 reference

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Identification of nitrosourea-resistant human rhabdomyosarcomas by in situ immunostaining of O6-methylguanine-DNA methyltransferase.

1 reference

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24 September 2018

Nuclear export of proteins: the role of nuclear retention.

1 reference

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Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats.

1 reference

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Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1 reference

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based on heuristic

inferred from PubMed ID database lookup

A method for simultaneous identification of human active and active-site alkylated O6-methylguanine-DNA methyltransferase and its possible application for monitoring human exposure to alkylating carcinogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/8670909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of purified human O6-alkylguanine-DNA alkyltransferase by alkylating agents or alkylated DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/8670909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular localization and function of DNA repair methyltransferase in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8670909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of arginine-128 to alanine abolishes the ability of human O6-alkylguanine-DNA alkyltransferase to repair methylated DNA but has no effect on its reaction with O6-benzylguanine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8670909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prevention of thymic lymphomas in transgenic mice by human O6-alkylguanine-DNA alkyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8670909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-directed mutagenesis of glutamic acid 172 to glutamine completely inactivated human O6-alkylguanine-DNA-alkyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8670909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The properties of O 6 -methylguanine in templates for RNA polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8670909

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1996.TB00778.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8670909%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8670909%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8670909%20AND%20SRC:MED&resulttype=core&format=json

16 October 2019

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