Tying the knot: the cystine signature and molecular-recognition processes of the vascular endothelial growth factor family of angiogenic cytokines. (Q35895234)

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scientific article published on 7 October 2011

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English	Tying the knot: the cystine signature and molecular-recognition processes of the vascular endothelial growth factor family of angiogenic cytokines.	scientific article published on 7 October 2011

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scholarly article

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12 February 2020

4 references

Europe PubMed Central

20 August 2020

26 August 2020

12 September 2020

Tying the knot: the cystine signature and molecular-recognition processes of the vascular endothelial growth factor family of angiogenic cytokines (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21917115%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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cell surface receptor

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31 July 2019

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28 September 2019

inorganic compound

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4 November 2019

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19 November 2019

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20 November 2019

membrane protein

1 reference

15 December 2019

vascular endothelial growth factor A

1 reference

20 August 2020

signal transduction

1 reference

26 August 2020

1 reference

12 September 2020

molecular knots

1 reference

based on heuristic

inferred from title

K. Ravi Acharya

2

1 reference

Europe PubMed Central

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12 February 2020

author name string

Shalini Iyer

1

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language of work or name

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publication date

7 October 2011

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12 February 2020

1 November 2011

3 references

20 August 2020

26 August 2020

12 September 2020

10 references

31 July 2019

28 September 2019

4 November 2019

19 November 2019

20 November 2019

15 December 2019

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21917115%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

20 August 2020

26 August 2020

12 September 2020

278

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12 February 2020

22

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12 February 2020

4304-4322

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12 February 2020

copyright license

Creative Commons Attribution 2.5 Generic

9 references

Europe PubMed Central

31 July 2019

Europe PubMed Central

28 September 2019

Europe PubMed Central

4 November 2019

Europe PubMed Central

19 November 2019

Europe PubMed Central

20 November 2019

Europe PubMed Central

15 December 2019

Europe PubMed Central

20 August 2020

Europe PubMed Central

26 August 2020

Europe PubMed Central

12 September 2020

Structural determinants of vascular endothelial growth factor-D receptor binding and specificity

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Structural Insights into the Binding of Vascular Endothelial Growth Factor-B by VEGFR-1D2: RECOGNITION AND SPECIFICITY

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Expression and function of vascular endothelial growth factor receptors (Flt-1 and Flk-1) in vascular adventitial fibroblasts

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Crystal structure of the Orf virus NZ2 variant of vascular endothelial growth factor-E. Implications for receptor specificity

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Crystal structure of human vascular endothelial growth factor-B: identification of amino acids important for receptor binding

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Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve

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The crystal structure of placental growth factor in complex with domain 2 of vascular endothelial growth factor receptor-1

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A set of loop-1 and -3 structures in the novel vascular endothelial growth factor (VEGF) family member, VEGF-ENZ-7, is essential for the activation of VEGFR-2 signaling

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Vascular endothelial growth factors encoded by Orf virus show surprising sequence variation but have a conserved, functionally relevant structure.

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Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis

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11 July 2018

The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor

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Vascular endothelial growth factor: a novel endocrine defensive response to hypoglycemia

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The neuropilins: multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis

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11 July 2018

Tyrosine residues 951 and 1059 of vascular endothelial growth factor receptor-2 (KDR) are essential for vascular permeability factor/vascular endothelial growth factor-induced endothelium migration and proliferation, respectively

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Evolution and classification of cystine knot-containing hormones and related extracellular signaling molecules

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VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

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The crystal structure of human placenta growth factor-1 (PlGF-1), an angiogenic protein, at 2.0 A resolution

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Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration

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11 July 2018

Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia

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Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen

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Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers

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VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

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Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.

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Signalling mechanisms in the regulation of vascular cell migration

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Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR

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Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family

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Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor

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Identification of a new endothelial cell growth factor receptor tyrosine kinase

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FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines

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Vascular endothelial growth factor is essential for corpus luteum angiogenesis.

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21 January 2018

The neural tube patterns vessels developmentally using the VEGF signaling pathway.

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21 January 2018

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08350.X

21 January 2018

VEGF gene and phenotype relation with Alzheimer's disease and mild cognitive impairment.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08350.X

21 January 2018

Expression levels of vascular endothelial growth factor and its receptors in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08350.X

21 January 2018

A novel type of vascular endothelial growth factor, VEGF-E (NZ-7 VEGF), preferentially utilizes KDR/Flk-1 receptor and carries a potent mitotic activity without heparin-binding domain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08350.X

21 January 2018

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08350.X

21 January 2018

Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08350.X

21 January 2018

Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08350.X

21 January 2018

The protein kinase MEK1/2 mediate vascular endothelial growth factor- and histamine-induced hyperpermeability in porcine coronary venules

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08350.X

21 January 2018

Vascular endothelial growth factor increases microvascular permeability via a Ca(2+)-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328748

24 September 2018

Flt-1 but not KDR/Flk-1 tyrosine kinase is a receptor for placenta growth factor, which is related to vascular endothelial growth factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328748

24 September 2018

Effects of vascular endothelial growth factor (VEGF) on motor neuron degeneration

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08350.X

21 January 2018

Vascular endothelial growth factor-D expression in human atherosclerotic lesions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08350.X

21 January 2018

Viral Vascular Endothelial Growth Factors Vary Extensively in Amino Acid Sequence, Receptor-binding Specificities, and the Ability to Induce Vascular Permeability yet Are Uniformly Active Mitogens

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08350.X

21 January 2018

Placenta growth factor is induced in human keratinocytes during wound healing

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The von Hippel-Lindau Gene Product Inhibits Vascular Permeability Factor/Vascular Endothelial Growth Factor Expression in Renal Cell Carcinoma by Blocking Protein Kinase C Pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide is an upstream signal of vascular endothelial growth factor-induced extracellular signal-regulated kinase1/2 activation in postcapillary endothelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VEGF upregulates ecNOS message, protein, and NO production in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular endothelial growth factor upregulates the expression of matrix metalloproteinases in vascular smooth muscle cells: role of flt-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of peripheral angiogenesis by vascular endothelial growth factor (VEGF)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt signaling mediates VEGF/VPF vascular permeability in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small GTP-Binding Protein Rac Is an Essential Mediator of Vascular Endothelial Growth Factor-Induced Endothelial Fenestrations and Vascular Permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topological similarities in TGF-beta 2, PDGF-BB and NGF define a superfamily of polypeptide growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structures of novel vascular endothelial growth factors (VEGF) from snake venoms: insight into selective VEGF binding to kinase insert domain-containing receptor but not to fms-like tyrosine kinase-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the heparin-binding region of snake venom vascular endothelial growth factor (VEGF-F) and its blocking of VEGF-A165.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anti-angiogenic VEGF isoform VEGF165b transiently increases hydraulic conductivity, probably through VEGF receptor 1 in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21917115

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1742-4658.2011.08350.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21917115%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21917115%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21917115%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

ResearchGate publication ID

0 references

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