Pharmacogenetics and drug development: the path to safer and more effective drugs (Q35889605)

10 August 2017

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title

Pharmacogenetics and drug development: the path to safer and more effective drugs (English)

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10 August 2017

Allen D Roses

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10 August 2017

publication date

1 September 2004

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10 August 2017

published in

Nature Reviews Genetics

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10 August 2017

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10 August 2017

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10 August 2017

page(s)

645-656

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Association study designs for complex diseases

10 August 2017

cites work

1 reference

Candidate-gene approaches for studying complex genetic traits: practical considerations

21 January 2018

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Linkage disequilibrium and the mapping of complex human traits

21 January 2018

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Pharmacogenetics goes genomic

21 January 2018

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Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium

21 January 2018

1 reference

A first-generation linkage disequilibrium map of human chromosome 22

21 January 2018

1 reference

Medical applications of haplotype-based SNP maps: learning to walk before we run.

21 January 2018

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Genome-based pharmacogenetics and the pharmaceutical industry

21 January 2018

1 reference

21 January 2018

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Fulfilling the promise: drug discovery in the post-genomic era.

21 January 2018

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Implications of the human genome for understanding human biology and medicine

21 January 2018

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Single-nucleotide polymorphism alleles in the insulin receptor gene are associated with typical migraine.

21 January 2018

1 reference

Linkage of essential hypertension to chromosome 18q.

21 January 2018

1 reference

Clinical research: perceptions, reality, and proposed solutions. National Institutes of Health Director's Panel on Clinical Research

21 January 2018

1 reference

Target selection for structural genomics

21 January 2018

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Pharmacophylogenomics: genes, evolution and drug targets

21 January 2018

1 reference

The impact of genomics on drug discovery

21 January 2018

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Drug discovery: a historical perspective

21 January 2018

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The SNP Consortium website: past, present and future

21 January 2018

1 reference

Techniques patents for SNP genotyping

21 January 2018

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Modern biomedical research: an internally self-consistent universe with little contact with medical reality?

21 January 2018

1 reference

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

21 January 2018

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EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

21 January 2018

1 reference

A common polymorphism of the growth hormone receptor is associated with increased responsiveness to growth hormone.

21 January 2018

1 reference

Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids

21 January 2018

1 reference

Placebo effect and placebos: what are we talking about? Some conceptual and historical considerations

21 January 2018

1 reference

Impact of placebo assignment in clinical trials of Parkinson's disease

21 January 2018

1 reference

Protein kinase inhibitors: insights into drug design from structure.

21 January 2018

1 reference

Clinical Experience with Trastuzumab (Herceptin)

21 January 2018

1 reference

Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map.

21 January 2018

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Pharmacogenetics of treatment with leukotriene modifiers

21 January 2018

1 reference

A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia.

21 January 2018

1 reference

The International HapMap Project

21 January 2018

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Pharmacogenetics and Pharmacogenomics in Drug Development and Regulatory Decision Making: Report of the First FDA‐PWG‐PhRMA‐DruSafe Workshop

21 January 2018

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Pharmacogenetics and public policy: expert views in Europe and North America

21 January 2018

1 reference

Genome scans and candidate gene approaches in the study of common diseases and variable drug responses

21 January 2018

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21 January 2018

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Identification of a pharmacogenetic effect by linkage disequilibrium mapping

31 March 2020

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31 March 2020

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Transgenic gene knock-outs: functional genomics and therapeutic target selection

31 March 2020

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Attrition and Translation

31 March 2020

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Family consent and the pursuit of better medicines through genetic research

31 March 2020

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The Arg972 variant in insulin receptor substrate-1 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.

31 March 2020

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A 4-Mb high-density single nucleotide polymorphism-based map around human APOE

31 March 2020

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Race, distributive justice and the promise of pharmacogenomics: ethical considerations

31 March 2020

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The potential and limitations of personalized medicine in the doctor–patient relationship

31 March 2020

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Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment

31 March 2020

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Clinical application of pharmacogenetics

31 March 2020

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2025: the practice of neurology: back from the future

31 March 2020

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Pharmacogenetics: ethical issues and policy options

31 March 2020

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Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease.

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1432

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release_lkqgtta46vbc7c6fprxvpaprh4

10 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lkqgtta46vbc7c6fprxvpaprh4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference