Clinical data sets of human immunodeficiency virus type 1 reverse transcriptase-resistant mutants explained by a mathematical model. (Q35874788)

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22 October 2019

title

Clinical data sets of human immunodeficiency virus type 1 reverse transcriptase-resistant mutants explained by a mathematical model (English)

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22 October 2019

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Stilianakis NI

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22 October 2019

Boucher CA

1 reference

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22 October 2019

De Jong MD

1 reference

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22 October 2019

Van Leeuwen R

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22 October 2019

Schuurman R

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22 October 2019

De Boer RJ

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22 October 2019

language of work or name

English

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publication date

1 January 1997

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22 October 2019

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22 October 2019

volume

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22 October 2019

issue

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22 October 2019

page(s)

161-168

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Human immunodeficiency virus fitness in vivo: calculations based on a single zidovudine resistance mutation at codon 215 of reverse transcriptase

22 October 2019

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1 reference

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27 July 2018

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Host-parasite dynamics and outgrowth of virus containing a single K70R amino acid change in reverse transcriptase are responsible for the loss of human immunodeficiency virus type 1 RNA load suppression by zidovudine

27 July 2018

1 reference

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HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

27 July 2018

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HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

27 July 2018

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Multifactorial nature of human immunodeficiency virus disease: implications for therapy

27 July 2018

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27 July 2018

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Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy

27 July 2018

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HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

27 July 2018

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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

27 July 2018

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In vivo estimates of division and death rates of human T lymphocytes

27 July 2018

1 reference

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Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase

27 July 2018

1 reference

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Kinetics of pharmacologic response

27 July 2018

1 reference

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Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

27 July 2018

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HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy

27 July 2018

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Effect of stage of disease and drug dose on zidovudine susceptibilities of isolates of human immunodeficiency virus

27 July 2018

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Sources of variability in repeated T-helper lymphocyte counts from human immunodeficiency virus type 1-infected patients: total lymphocyte count fluctuations and diurnal cycle are important.

27 July 2018

1 reference

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Zidovudine resistance predicted by direct detection of mutations in DNA from HIV-infected lymphocytes

27 July 2018

1 reference

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Competition between zidovudine-sensitive and zidovudine-resistant strains of HIV.

27 July 2018

1 reference

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Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine

27 July 2018

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Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive subjects

27 July 2018

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Nucleotide substitution patterns can predict the requirements for drug-resistance of HIV-1 proteins.

27 July 2018

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Anti-CD4 therapy for AIDS suggested by mathematical models.

24 September 2018

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Thymic-independent T cell regeneration occurs via antigen-driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing.

24 September 2018

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Dynamics of HIV infection of CD4+ T cells.

24 September 2018

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Quasispecies dynamics and the emergence of drug resistance during zidovudine therapy of HIV infection.

24 September 2018

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Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant virus populations in persons treated with lamivudine (3TC).

24 September 2018

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24 September 2018

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Increased numbers of primed activated CD8+CD38+CD45RO+ T cells predict the decline of CD4+ T cells in HIV-1-infected patients

24 September 2018

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HIV-1 RNA serum-load and resistant viral genotypes during early zidovudine therapy

24 September 2018

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12 December 2020

Treatment with lamivudine, zidovudine, or both in HIV-positive patients with 200 to 500 CD4+ cells per cubic millimeter. North American HIV Working Party

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12 December 2020

Zidovudine sensitivity of human immunodeficiency viruses from high-risk, symptom-free individuals during therapy

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12 December 2020

Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS

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12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8985335%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

PubMed publication ID

8985335

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8985335%20AND%20SRC:MED&resulttype=core&format=json