The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming (Q35865881)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26179207%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

title

The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming (English)

1 reference

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19 February 2020

1 reference

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19 February 2020

Enrique Fuentes-Mattei

1 reference

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19 February 2020

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19 February 2020

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19 February 2020

1 reference

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19 February 2020

1 reference

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19 February 2020

Huamin Wang

1 reference

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19 February 2020

Ping-Chieh Chou

1 reference

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19 February 2020

Guermarie Velazquez-Torres

1 reference

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19 February 2020

Ismael Samudio

1 reference

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19 February 2020

Kenneth Parreno

1 reference

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19 February 2020

Yaling Huang

1 reference

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19 February 2020

Chieh Tseng

1 reference

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19 February 2020

Thuy Vu

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19 February 2020

Chris Gully

1 reference

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19 February 2020

Chun-Hui Su

1 reference

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19 February 2020

Edward Wang

1 reference

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19 February 2020

Jian Chen

1 reference

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19 February 2020

Hyun-Ho Choi

1 reference

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19 February 2020

Ji-Hyun Shin

1 reference

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19 February 2020

Christine Shiang

1 reference

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19 February 2020

Brian Grabiner

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19 February 2020

Stephen Skerl

1 reference

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19 February 2020

Yiping Shao

1 reference

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19 February 2020

Dianna Cody

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19 February 2020

Jorge Delacerda

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19 February 2020

Charles Kingsley

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19 February 2020

Douglas Webb

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19 February 2020

Colin Carlock

1 reference

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19 February 2020

Zhongguo Zhou

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19 February 2020

Yun-Chih Hsieh

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19 February 2020

Jaehyuk Lee

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19 February 2020

Andrew Elliott

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19 February 2020

Marc Ramirez

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19 February 2020

John Hazle

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19 February 2020

Yongxing Wang

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19 February 2020

Lei Li

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19 February 2020

Shaofan Weng

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19 February 2020

Nibal Rizk

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19 February 2020

Yu Ye Wen

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19 February 2020

Hua Wang

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19 February 2020

Aijun Zhang

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19 February 2020

Xuefeng Xia

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19 February 2020

Yun Wu

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19 February 2020

Wei Yang

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19 February 2020

Lajos Pusztai

1 reference

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19 February 2020

Sai-Ching Yeung

1 reference

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19 February 2020

Mong-Hong Lee

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19 February 2020

language of work or name

English

0 references

publication date

16 July 2015

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19 February 2020

published in

Nature Communications

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19 February 2020

volume

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19 February 2020

page(s)

7530

1 reference

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COP1 enhances ubiquitin-mediated degradation of p27Kip1 to promote cancer cell growth.

19 February 2020

cites work

1 reference

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CSN6 deregulation impairs genome integrity in a COP1-dependent pathway

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Circadian Clock Gene CRY2 Degradation Is Involved in Chemoresistance of Colorectal Cancer.

27 July 2018

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CSN6 drives carcinogenesis by positively regulating Myc stability.

27 July 2018

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Effects of obesity on transcriptomic changes and cancer hallmarks in estrogen receptor-positive breast cancer

27 July 2018

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Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies

27 July 2018

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Metabolic imaging of patients with prostate cancer using hyperpolarized [1-¹³C]pyruvate

27 July 2018

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How cancer metabolism is tuned for proliferation and vulnerable to disruption

27 July 2018

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27 July 2018

Mitochondria and cancer

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Aurora B kinase phosphorylates and instigates degradation of p53

27 July 2018

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Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

27 July 2018

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13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression

27 July 2018

1 reference

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COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ

27 July 2018

1 reference

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14-3-3σ Exerts Tumor-Suppressor Activity Mediated by Regulation of COP1 Stability

27 July 2018

1 reference

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Rewiring of glycolysis in cancer cell metabolism

27 July 2018

1 reference

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Nuclear export regulation of COP1 by 14-3-3σ in response to DNA damage

27 July 2018

1 reference

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Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

27 July 2018

1 reference

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Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors

27 July 2018

1 reference

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Rethinking the Warburg effect with Myc micromanaging glutamine metabolism

27 July 2018

1 reference

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

27 July 2018

1 reference

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Roles of p53, MYC and HIF-1 in regulating glycolysis - the seventh hallmark of cancer

27 July 2018

1 reference

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The role of autocrine motility factor in tumor and tumor microenvironment

27 July 2018

1 reference

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Down-regulation of phosphoglucose isomerase/autocrine motility factor results in mesenchymal-to-epithelial transition of human lung fibrosarcoma cells

27 July 2018

1 reference

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Regulation of the p53-MDM2 pathway by 14-3-3 sigma and other proteins.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Structural determinants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: a comparison of the X-ray crystal structures of all human 14-3-3 isoforms

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis

27 July 2018

1 reference

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The crystal structure of the non-liganded 14-3-3sigma protein: insights into determinants of isoform specific ligand binding and dimerization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

A structural basis for 14-3-3sigma functional specificity.

27 July 2018

1 reference

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Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity

27 July 2018

1 reference

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Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays

27 July 2018

1 reference

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Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases

27 July 2018

1 reference

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On respiratory impairment in cancer cells

27 July 2018

1 reference

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On the Origin of Cancer Cells

27 July 2018

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Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth

27 July 2018

1 reference

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Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis.

27 July 2018

1 reference

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14-3-3 proteins: structure, function, and regulation

27 July 2018

1 reference

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High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Hyperpolarized 13C MRI and PET: in vivo tumor biochemistry

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Hallmarks of Cancer: The Next Generation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Glutaminolysis: Supplying carbon or nitrogen or both for cancer cells?

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

MYC-induced cancer cell energy metabolism and therapeutic opportunities

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Understanding the Warburg effect: the metabolic requirements of cell proliferation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Evaluation of lactate and alanine as metabolic biomarkers of prostate cancer using 1H HR-MAS spectroscopy of biopsy tissues

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Pyruvate and oxygen consumption throughout the growth and development of murine oocytes

24 September 2018

1 reference

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Metabolic targeting as an anticancer strategy: dawn of a new era?

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

14-3-3sigma, a p53 regulator, suppresses tumor growth of nasopharyngeal carcinoma.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Transcriptional regulation and transformation by Myc proteins

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Why do cancers have high aerobic glycolysis?

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

14-3-3σ Positively Regulates p53 and Suppresses Tumor Growth

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Oncogenic alterations of metabolism

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4507299

Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26179207

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS8530

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26179207%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26179207%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

PubMed publication ID

26179207

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26179207%20AND%20SRC:MED&resulttype=core&format=json