Nuclear receptor variants in liver disease (Q35864839)

10 August 2017

Nuclear receptor variants in liver disease. (English)

1 reference

10 August 2017

Roman Müllenbach

1 reference

10 August 2017

Susanne N Weber

series ordinal

1 reference

10 August 2017

Frank Lammert

series ordinal

1 reference

10 August 2017

21 December 2011

1 reference

10 August 2017

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10 August 2017

2012

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10 August 2017

934707

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Creative Commons Attribution 3.0 Unported

10 August 2017

start time

1 January 2012

1 reference

April 2022 Public Data File from Crossref

copyrighted

1 reference

April 2022 Public Data File from Crossref

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Nuclear receptors in liver disease.

11 July 2018

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Vitamin D receptor gene as a candidate gene for Parkinson disease

11 July 2018

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Functional Significance of Vitamin D Receptor FokI Polymorphism in Human Breast Cancer Cells

11 July 2018

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SHP-dependent and -independent induction of peroxisome proliferator-activated receptor-γ by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory phenotype of liver myofibroblasts

11 July 2018

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11 July 2018

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11 July 2018

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Lack of association between peroxisome proliferator-activated receptors alpha and gamma2 polymorphisms and progressive liver damage in patients with non-alcoholic fatty liver disease: a case control study

11 July 2018

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Coactivators in PPAR-Regulated Gene Expression

11 July 2018

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Transcriptome sequencing, microarray, and proteomic analyses reveal cellular and metabolic impact of hepatitis C virus infection in vitro

11 July 2018

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Pharmacogenetics of drug-induced liver injury

11 July 2018

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Vitamin D receptor gene polymorphisms and hepatocellular carcinoma in alcoholic cirrhosis

11 July 2018

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A novel bile acid-activated vitamin D receptor signaling in human hepatocytes

11 July 2018

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Ethical issues of predictive genetic testing for diabetes

11 July 2018

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Mapping complex disease traits with global gene expression

11 July 2018

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Mechanism of vitamin D receptor inhibition of cholesterol 7alpha-hydroxylase gene transcription in human hepatocytes

11 July 2018

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Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing

11 July 2018

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Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

11 July 2018

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Common variants at 30 loci contribute to polygenic dyslipidemia

11 July 2018

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Genetic determinants in hepatic fibrosis: from experimental models to fibrogenic gene signatures in humans

11 July 2018

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Transactivation of the hepatitis B virus core promoter by the nuclear receptor FXRalpha

11 July 2018

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Targeting bile-acid signalling for metabolic diseases

11 July 2018

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Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk

11 July 2018

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Epigenetic inhibition of nuclear receptor small heterodimer partner is associated with and regulates hepatocellular carcinoma growth

11 July 2018

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Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump

11 July 2018

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Compromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1.

11 July 2018

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Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy

11 July 2018

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Large-scale in silico mapping of complex quantitative traits in inbred mice

11 July 2018

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Nuclear receptor coregulators and human disease

11 July 2018

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Bile Acids Promote the Expression of Hepatitis C Virus in Replicon-Harboring Cells

11 July 2018

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Tissue-specific transcriptional regulation has diverged significantly between human and mouse

11 July 2018

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Alterations in xenobiotic metabolism in the long-lived Little mice

11 July 2018

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Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

11 July 2018

1 reference

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A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

11 July 2018

1 reference

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Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A gene

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Combining information from common type 2 diabetes risk polymorphisms improves disease prediction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network

11 July 2018

1 reference

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An integrative genomics approach to infer causal associations between gene expression and disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Polymorphisms of human nuclear receptors that control expression of drug-metabolizing enzymes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Prevention of cholesterol gallstone disease by FXR agonists in a mouse model.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

The fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 element

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Control of pancreas and liver gene expression by HNF transcription factors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

The normal liver harbors the vitamin D nuclear receptor in nonparenchymal and biliary epithelial cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

A missense mutation in hepatocyte nuclear factor-4 alpha, resulting in a reduced transactivation activity, in human late-onset non-insulin-dependent diabetes mellitus

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Differential regulation of the pre-C and pregenomic promoters of human hepatitis B virus by members of the nuclear receptor superfamily

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes

11 July 2018

1 reference

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Vitamin D receptor gene polymorphisms in a group of postmenopausal Turkish women: association wıth bone mineral density

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

Maternal vitamin D receptor genetic variation contributes to infant birthweight among black mothers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

Genetic association of vitamin D receptor polymorphisms with autoimmune hepatitis and primary biliary cirrhosis in the Chinese

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

Vitamin D receptor polymorphisms are associated with increased susceptibility to primary biliary cirrhosis in Japanese and Italian populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

Genetic association of vitamin D receptor polymorphisms with primary biliary cirrhosis and autoimmune hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

Variation of the gene encoding the nuclear bile salt receptor FXR and gallstone susceptibility in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

A Pro12Ala polymorphism in the human peroxisome proliferator-activated receptor-gamma 2 is associated with combined hyperlipidaemia in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

The Pro12Ala PPARgamma2 variant determines metabolism at the gene-environment interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

Effect of peroxisome proliferator-activated receptors-gamma and co-activator-1alpha genetic polymorphisms on plasma adiponectin levels and susceptibility of non-alcoholic fatty liver disease in Chinese people

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

Influence of polygenetic polymorphisms on the susceptibility to non-alcoholic fatty liver disease of Chinese people.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

The nuclear receptor PXR gene variants are associated with liver injury in nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

The role of bile acid retention and a common polymorphism in the ABCB11 gene as host factors affecting antiviral treatment response in chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

A common polymorphism in the ABCB11 gene is associated with advanced fibrosis in hepatitis C but not in non-alcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

Enhancement of genotype 1 hepatitis C virus replication by bile acids through FXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

Relationship between daily dose of oral medications and idiosyncratic drug-induced liver injury: search for signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

A role for the pregnane X receptor in flucloxacillin-induced liver injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

Who should have genetic testing for maturity‐onset diabetes of the young?

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Colonic epithelial cell proliferation decreases with increasing levels of serum 25-hydroxy vitamin D.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3317184

Vitamin D receptor gene polymorphism associated with inflammatory bowel disease in New Zealand males

24 September 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

A genetic polymorphism of the peroxisome proliferator-activated receptor gamma gene influences plasma leptin levels in obese humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F934707

Association between vitamin D receptor, CCR5, TNF-alpha and TNF-beta gene polymorphisms and HBV infection and severity of liver disease

21 January 2018

1 reference

12 December 2020

Influence of hepatocyte nuclear factor 4alpha (HNF4alpha) gene variants on the risk of type 2 diabetes: a meta-analysis in 49,577 individuals

1 reference

12 December 2020

From QTL to gene: the harvest begins

1 reference

12 December 2020

Vitamin D receptor gene polymorphism and ulcerative colitis susceptibility in Han Chinese

1 reference

12 December 2020

A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression

1 reference

12 December 2020

The pregnane X receptor: from bench to bedside

1 reference

12 December 2020

Identifiers

DOI

10.1155/2012/934707

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

22523693

1 reference