Mechanisms of B cell autoimmunity in SLE. (Q35840704)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22078750%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

review article

1 reference

PubMed publication ID

22078750

title

Mechanisms of B cell autoimmunity in SLE (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22078750%20AND%20SRC:MED&resulttype=core&format=json

systemic lupus erythematosus

16 January 2020

main subject

1 reference

18 October 2019

1 reference

18 October 2019

1 reference

18 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22078750%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Thomas Dörner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22078750%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Peter E Lipsky

series ordinal

1 reference

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16 January 2020

publication date

27 October 2011

7 references

12 March 2019

13 March 2019

17 June 2019

30 June 2019

12 October 2019

18 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22078750%20AND%20SRC:MED&resulttype=core&format=json

Arthritis Research and Therapy

16 January 2020

published in

7 references

12 March 2019

13 March 2019

17 June 2019

30 June 2019

12 October 2019

18 October 2019

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16 January 2020

volume

1 reference

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16 January 2020

issue

1 reference

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16 January 2020

page(s)

243

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22078750%20AND%20SRC:MED&resulttype=core&format=json

Comparison of Antibody Repertoires Produced by HIV-1 Infection, Other Chronic and Acute Infections, and Systemic Autoimmune Disease

16 January 2020

cites work

1 reference

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Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes

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Dendritic cells in lupus are not required for activation of T and B cells but promote their expansion, resulting in tissue damage

11 July 2018

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Epratuzumab targeting of CD22 affects adhesion molecule expression and migration of B-cells in systemic lupus erythematosus.

11 July 2018

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Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells.

11 July 2018

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What can we learn from genetic studies of systemic lupus erythematosus? Implications of genetic heterogeneity among populations in SLE.

11 July 2018

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11 July 2018

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Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity

11 July 2018

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11 July 2018

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The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

11 July 2018

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Secondary immunization generates clonally related antigen-specific plasma cells and memory B cells.

11 July 2018

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Tocilizumab in systemic lupus erythematosus: data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study

11 July 2018

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CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients

11 July 2018

1 reference

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B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

11 July 2018

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Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial

11 July 2018

1 reference

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Effect of long-term belimumab treatment on B cells in systemic lupus erythematosus: extension of a phase II, double-blind, placebo-controlled, dose-ranging study

11 July 2018

1 reference

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Current status on B-cell depletion therapy in autoimmune diseases other than rheumatoid arthritis

11 July 2018

1 reference

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Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation

11 July 2018

1 reference

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Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus

11 July 2018

1 reference

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A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice

11 July 2018

1 reference

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Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.

11 July 2018

1 reference

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Interleukin 21 as a target of intervention in autoimmune disease

11 July 2018

1 reference

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AIRE regulates T-cell-independent B-cell responses through BAFF.

11 July 2018

1 reference

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B-cell tolerance checkpoints in health and autoimmunity

11 July 2018

1 reference

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Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors

11 July 2018

1 reference

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A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses

11 July 2018

1 reference

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Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

11 July 2018

1 reference

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Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice

11 July 2018

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Fc-receptors as regulators of immunity.

11 July 2018

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Clearance deficiency and systemic lupus erythematosus (SLE).

11 July 2018

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Efficacy of rituximab (anti-CD20) for refractory systemic lupus erythematosus involving the central nervous system

11 July 2018

1 reference

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Competence and competition: the challenge of becoming a long-lived plasma cell

11 July 2018

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Persistent expression of autoantibodies in SLE patients in remission

11 July 2018

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B-cell targeting in rheumatoid arthritis and other autoimmune diseases

11 July 2018

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Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome

11 July 2018

1 reference

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Selective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease

11 July 2018

1 reference

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Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus.

11 July 2018

1 reference

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Cellular and genetic mechanisms of self tolerance and autoimmunity

11 July 2018

1 reference

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A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

11 July 2018

1 reference

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Defective B cell tolerance checkpoints in systemic lupus erythematosus

11 July 2018

1 reference

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Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

11 July 2018

1 reference

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Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions.

11 July 2018

1 reference

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Perturbations of peripheral B lymphocyte homoeostasis in children with systemic lupus erythematosus

11 July 2018

1 reference

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Predominant autoantibody production by early human B cell precursors

11 July 2018

1 reference

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AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

11 July 2018

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The heterogeneity shown by human plasma cells from tonsil, blood, and bone marrow reveals graded stages of increasing maturity, but local profiles of adhesion molecule expression

11 July 2018

1 reference

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Immunoglobulin variable-region gene usage in systemic autoimmune diseases

11 July 2018

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A pivotal role for the natural interferon alpha-producing cells (plasmacytoid dendritic cells) in the pathogenesis of lupus

11 July 2018

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A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus

11 July 2018

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ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

11 July 2018

1 reference

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Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells

11 July 2018

1 reference

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Immunoglobulin kappa chain receptor editing in systemic lupus erythematosus

11 July 2018

1 reference

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Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus

11 July 2018

1 reference

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Molecular characterization of a somatically mutated anti-DNA antibody bearing two systemic lupus erythematosus-related idiotypes

11 July 2018

1 reference

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HLA antigens in Italian patients with systemic lupus erythematosus: evidence for the association of DQw2 with the autoantibody response to extractable nuclear antigens.

11 July 2018

1 reference

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Analysis of immunoglobulin variable region genes from human IgG anti-DNA hybridomas

11 July 2018

1 reference

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The efficacy and safety of abatacept in patients with non-life-threatening manifestations of systemic lupus erythematosus: results of a twelve-month, multicenter, exploratory, phase IIb, randomized, double-blind, placebo-controlled trial

11 July 2018

1 reference

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Clonal expansion of B-cells in human systemic lupus erythematosus: evidence from studies before and after therapeutic B-cell depletion

24 September 2018

1 reference

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HLA-DRhigh/CD27high plasmablasts indicate active disease in patients with systemic lupus erythematosus.

24 September 2018

1 reference

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Blood-borne human plasma cells in steady state are derived from mucosal immune responses

24 September 2018

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Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system

24 September 2018

1 reference

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A new memory CD27-IgG+ B cell population in peripheral blood expressing VH genes with low frequency of somatic mutation

24 September 2018

1 reference

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Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response

24 September 2018

1 reference

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Correlation between circulating CD27high plasma cells and disease activity in patients with systemic lupus erythematosus

24 September 2018

1 reference

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Maintenance of serological memory by polyclonal activation of human memory B cells

24 September 2018

1 reference

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Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus

24 September 2018

1 reference

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Identification and characterization of a human CD5+ pre-naive B cell population

24 September 2018

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12 December 2020

B cells in autoimmunity

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12 December 2020

Rituximab: wanted dead or alive...

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12 December 2020

Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus

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12 December 2020

Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus

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12 December 2020

Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus

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12 December 2020

Bystander apoptosis triggers dendritic cell maturation and antigen-presenting function

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12 December 2020

The genetics of human systemic lupus erythematosus

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12 December 2020

A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus

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12 December 2020

Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy

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12 December 2020

Expression of CD80/86 on B cells is essential for autoreactive T cell activation and the development of arthritis

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12 December 2020

Differential effects of epratuzumab on peripheral blood B cells of patients with systemic lupus erythematosus versus normal controls

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12 December 2020

Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: delineation by expression of CD27, IgD, and CD95

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12 December 2020

Identifiers

DOI

10.1186/AR3433

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22078750%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22078750%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

22078750

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22078750%20AND%20SRC:MED&resulttype=core&format=json