Molecular imaging in Alzheimer's disease: new perspectives on biomarkers for early diagnosis and drug development. (Q35840623)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22136152%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Molecular imaging in Alzheimer's disease: new perspectives on biomarkers for early diagnosis and drug development (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22136152%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22136152%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Agneta Nordberg

1 reference

10 August 2017

language of work or name

English

0 references

publication date

2 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22136152%20AND%20SRC:MED&resulttype=core&format=json

Alzheimers Research & Therapy

17 January 2020

published in

1 reference

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17 January 2020

volume

1 reference

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17 January 2020

issue

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17 January 2020

page(s)

1 reference

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Evidence for astrocytosis in prodromal Alzheimer disease provided by 11C-deuterium-L-deprenyl: a multitracer PET paradigm combining 11C-Pittsburgh compound B and 18F-FDG.

17 January 2020

cites work

1 reference

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The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects

11 July 2018

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In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18)

11 July 2018

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The Alzheimer's Disease Neuroimaging Initiative positron emission tomography core

11 July 2018

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Nicotinic acetylcholine receptor interaction with beta-amyloid: molecular, cellular, and physiological consequences

11 July 2018

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11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

11 July 2018

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The use of PET in Alzheimer disease

11 July 2018

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Inflammation in Alzheimer's disease: relevance to pathogenesis and therapy

11 July 2018

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Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

11 July 2018

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Increased metabolic vulnerability in early-onset Alzheimer's disease is not related to amyloid burden

11 July 2018

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Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: implications for future clinical trials of Alzheimer's disease

11 July 2018

1 reference

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Pittsburgh compound B imaging and prediction of progression from cognitive normality to symptomatic Alzheimer disease

11 July 2018

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Activated astrocytes: a therapeutic target in Alzheimer's disease?

11 July 2018

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Relationships between biomarkers in aging and dementia

11 July 2018

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Systemic inflammation and disease progression in Alzheimer disease

11 July 2018

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Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study.

11 July 2018

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Amyloid imaging in mild cognitive impairment subtypes.

11 July 2018

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11 July 2018

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Comparison of 18F-FDG and PiB PET in cognitive impairment

11 July 2018

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Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease

11 July 2018

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Beta amyloid in Alzheimer's disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid

11 July 2018

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Interaction of the amyloid imaging tracer FDDNP with hallmark Alzheimer's disease pathologies

11 July 2018

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11 July 2018

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Microglial activation and amyloid deposition in mild cognitive impairment: a PET study

11 July 2018

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Neuropathology and cognitive impairment in Alzheimer disease: a complex but coherent relationship

11 July 2018

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Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease

11 July 2018

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Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease

11 July 2018

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Acetylcholine receptors in dementia and mild cognitive impairment.

11 July 2018

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Amyloid imaging in Alzheimer's disease

11 July 2018

1 reference

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Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria

11 July 2018

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PET imaging of amyloid deposition in patients with mild cognitive impairment

11 July 2018

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A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

11 July 2018

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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

11 July 2018

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Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

11 July 2018

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PET imaging of amyloid in Alzheimer's disease.

11 July 2018

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Pathways towards and away from Alzheimer's disease

11 July 2018

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Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

11 July 2018

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11 July 2018

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Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

11 July 2018

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11 July 2018

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24 September 2018

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24 September 2018

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24 September 2018

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24 September 2018

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Dynamic changes in PET amyloid and FDG imaging at different stages of Alzheimer's disease

24 September 2018

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24 September 2018

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Pittsburgh compound-B and Alzheimer's disease biomarkers in CSF, plasma and urine: An exploratory study

24 September 2018

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High PIB retention in Alzheimer's disease is an early event with complex relationship with CSF biomarkers and functional parameters

24 September 2018

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Follow-up of [11C]PIB uptake and brain volume in patients with Alzheimer disease and controls

24 September 2018

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Relationship of cerebrospinal fluid markers to 11C-PiB and 18F-FDDNP binding

24 September 2018

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[(11)C]PIB-amyloid binding and levels of Abeta40 and Abeta42 in postmortem brain tissue from Alzheimer patients

24 September 2018

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PET amyloid ligand [11C]PIB uptake and cerebrospinal fluid beta-amyloid in mild cognitive impairment

24 September 2018

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Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

24 September 2018

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Assessment of beta-amyloid in a frontal cortical brain biopsy specimen and by positron emission tomography with carbon 11-labeled Pittsburgh Compound B.

24 September 2018

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Increased binding of peripheral benzodiazepine receptor in Alzheimer's disease measured by positron emission tomography with [11C]DAA1106.

24 September 2018

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Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism

24 September 2018

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PET amyloid ligand [11C]PIB uptake is increased in mild cognitive impairment

24 September 2018

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PET imaging of the in vivo brain acetylcholinesterase activity and nicotine binding in galantamine-treated patients with AD.

24 September 2018

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Changes in brain 11C-nicotine binding sites in patients with mild Alzheimer's disease following rivastigmine treatment as assessed by PET.

24 September 2018

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Inhibition of acetylcholinesterase in CSF versus brain assessed by 11C-PMP PET in AD patients treated with galantamine

24 September 2018

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Two-year follow-up of amyloid deposition in patients with Alzheimer's disease

24 September 2018

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PET imaging of cortical 11C-nicotine binding correlates with the cognitive function of attention in Alzheimer's disease

24 September 2018

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Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans

24 September 2018

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Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain.

24 September 2018

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High selective expression of alpha7 nicotinic receptors on astrocytes in the brains of patients with sporadic Alzheimer's disease and patients carrying Swedish APP 670/671 mutation: a possible association with neuritic plaques.

24 September 2018

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Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

24 September 2018

1 reference

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Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function

24 September 2018

1 reference

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Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer’s disease

24 September 2018

1 reference

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Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease

24 September 2018

1 reference

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In-vivo measurement of activated microglia in dementia

24 September 2018

1 reference

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18F-THK523: a novel in vivo tau imaging ligand for Alzheimer's disease

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FALZRT96

21 January 2018

Identifiers

DOI

10.1186/ALZRT96

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22136152%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

17 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22136152%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

22136152

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22136152%20AND%20SRC:MED&resulttype=core&format=json