Reprogramming patient-derived cells to study the epilepsies (Q35789597)

10 August 2017

1 reference

title

Reprogramming patient-derived cells to study the epilepsies (English)

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10 August 2017

1 reference

Jack M Parent

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10 August 2017

Stewart A Anderson

series ordinal

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10 August 2017

language of work or name

English

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publication date

24 February 2015

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10 August 2017

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10 August 2017

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10 August 2017

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10 August 2017

page(s)

360-366

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hPSC-derived maturing GABAergic interneurons ameliorate seizures and abnormal behavior in epileptic mice

10 August 2017

cites work

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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GABAergic interneuron transplants to study development and treat disease

12 July 2018

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Strain- and age-dependent hippocampal neuron sodium currents correlate with epilepsy severity in Dravet syndrome mice

12 July 2018

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Mutant astrocytes differentiated from Rett syndrome patients-specific iPSCs have adverse effects on wild-type neurons

12 July 2018

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Revisiting epilepsy and the electroencephalogram patterns in Angelman syndrome.

12 July 2018

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Decision making during interneuron migration in the developing cerebral cortex

12 July 2018

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12 July 2018

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Human iPSC-based modeling of late-onset disease via progerin-induced aging

12 July 2018

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12 July 2018

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SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients

12 July 2018

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Non-epithelial stem cells and cortical interneuron production in the human ganglionic eminences

12 July 2018

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Cerebral organoids model human brain development and microcephaly

12 July 2018

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Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism

12 July 2018

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Opportunities and challenges of pluripotent stem cell neurodegenerative disease models

12 July 2018

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12 July 2018

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Investigation of Rett syndrome using pluripotent stem cells

12 July 2018

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Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.

12 July 2018

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Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

12 July 2018

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A human Dravet syndrome model from patient induced pluripotent stem cells

12 July 2018

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Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits

12 July 2018

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Rett syndrome and epilepsy: an update for child neurologists

12 July 2018

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Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination

12 July 2018

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Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons

12 July 2018

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An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells

12 July 2018

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Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells

12 July 2018

1 reference

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Modeling neurodevelopmental disorders using human neurons

12 July 2018

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Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor

12 July 2018

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Signaling defects in iPSC-derived fragile X premutation neurons

12 July 2018

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Patterns of treatment response in newly diagnosed epilepsy.

12 July 2018

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Erosion of dosage compensation impacts human iPSC disease modeling

12 July 2018

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GABAergic interneuron migration and the evolution of the neocortex

12 July 2018

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Large-scale cellular-resolution gene profiling in human neocortex reveals species-specific molecular signatures

12 July 2018

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OSVZ progenitors in the human cortex: an updated perspective on neurodevelopmental disease

12 July 2018

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Using label-free screening technology to improve efficiency in drug discovery

12 July 2018

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New perspectives on the biology of fragile X syndrome

12 July 2018

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Differentiation and functional incorporation of embryonic stem cell-derived GABAergic interneurons in the dentate gyrus of mice with temporal lobe epilepsy.

12 July 2018

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Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome

12 July 2018

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Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome

12 July 2018

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Isogenic Pairs of Wild Type and Mutant Induced Pluripotent Stem Cell (iPSC) Lines from Rett Syndrome Patients as In Vitro Disease Model

12 July 2018

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Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises

12 July 2018

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Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome

12 July 2018

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The genetics of Dravet syndrome.

12 July 2018

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A bioinformatic assay for pluripotency in human cells

12 July 2018

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Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation

12 July 2018

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Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

12 July 2018

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Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines

12 July 2018

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Interneurons in the developing human neocortex

12 July 2018

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A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

12 July 2018

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Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues

12 July 2018

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Induced pluripotency: history, mechanisms, and applications

12 July 2018

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Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats

12 July 2018

1 reference

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Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells

12 July 2018

1 reference

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Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells

12 July 2018

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Clinical and genetic aspects of Angelman syndrome

12 July 2018

1 reference

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Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells

12 July 2018

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Direct conversion of fibroblasts to functional neurons by defined factors

12 July 2018

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Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome

12 July 2018

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Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures

12 July 2018

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Human induced pluripotent stem cells free of vector and transgene sequences

12 July 2018

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Generation of induced pluripotent stem cells from human blood

12 July 2018

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Disease-specific induced pluripotent stem cells

12 July 2018

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Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

12 July 2018

1 reference

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

12 July 2018

1 reference

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Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation

12 July 2018

1 reference

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Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

12 July 2018

1 reference

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

12 July 2018

1 reference

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Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain

12 July 2018

1 reference

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Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism

12 July 2018

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Origin of GABAergic neurons in the human neocortex

12 July 2018

1 reference

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Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells

12 July 2018

1 reference

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Embryonic stem cell lines derived from human blastocysts

12 July 2018

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Subcortical origins of human and monkey neocortical interneurons

12 July 2018

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Neural differentiation of Fragile X human Embryonic Stem Cells reveals abnormal patterns of development despite successful neurogenesis.

25 September 2018

1 reference

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CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.

25 September 2018

1 reference

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Human-induced pluripotent stem cells form functional neurons and improve recovery after grafting in stroke-damaged brain

25 September 2018

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A new subtype of progenitor cell in the mouse embryonic neocortex

25 September 2018

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Subregional specification of embryonic stem cell-derived ventral telencephalic tissues by timed and combinatory treatment with extrinsic signals

25 September 2018

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Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells.

25 September 2018

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Transplant of GABAergic precursors restores hippocampal inhibitory function in a mouse model of seizure susceptibility

25 September 2018

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Selective depletion of molecularly defined cortical interneurons in human holoprosencephaly with severe striatal hypoplasia

25 September 2018

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Epilepsy in fragile X syndrome

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483308

Young neurons from medial ganglionic eminence disperse in adult and embryonic brain

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483308

Thalamic interneurons and relay cells use complementary synaptic mechanisms for visual processing

25 September 2018

1 reference

Cognitive development in children with Dravet syndrome

21 January 2018

1 reference

Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader–Willi syndromes

21 January 2018

1 reference

Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits

21 January 2018

1 reference

Cognitive development in Dravet syndrome: A retrospective, multicenter study of 26 patients

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25710838

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NN.3944

1 reference

10 August 2017

1 reference

10 August 2017

1 reference