The alpha(2) integrin subunit-deficient mouse: a multifaceted phenotype including defects of branching morphogenesis and hemostasis (Q35747487)

10 August 2017

title

The alpha(2) integrin subunit-deficient mouse: a multifaceted phenotype including defects of branching morphogenesis and hemostasis (English)

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10 August 2017

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Jianchun Chen

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10 August 2017

Thomas G Diacovo

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10 August 2017

David G Grenache

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10 August 2017

Samuel A Santoro

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10 August 2017

Mary M Zutter

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10 August 2017

language of work or name

English

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publication date

1 July 2002

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The American Journal of Pathology

10 August 2017

published in

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10 August 2017

volume

161

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10 August 2017

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10 August 2017

page(s)

337-344

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Mammary epithelial cell-cycle progression via the alpha(2)beta(1) integrin: unique and synergistic roles of the alpha(2) cytoplasmic domain

10 August 2017

cites work

1 reference

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Pro-collagenase-1 (matrix metalloproteinase-1) binds the alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagen

12 July 2018

1 reference

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Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850700

alpha 2 integrin subunit cytoplasmic domain-dependent cellular migration requires p38 MAPK.

12 July 2018

1 reference

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Altered integrin expression and the malignant phenotype: the contribution of multiple integrated integrin receptors

12 July 2018

1 reference

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Mapping the glycoprotein Ib-binding site in the von willebrand factor A1 domain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850700

The ups and downs of alpha 2 beta 1-integrin expression: contributions to epithelial cell differentiation and the malignant phenotype.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850700

The activity of collagenase-1 is required for keratinocyte migration on a type I collagen matrix

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850700

A three-dimensional collagen lattice induces protein kinase C-zeta activity: role in alpha2 integrin and collagenase mRNA expression

12 July 2018

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Loss of MDCK cell alpha 2 beta 1 integrin expression results in reduced cyst formation, failure of hepatocyte growth factor/scatter factor-induced branching morphogenesis, and increased apoptosis

12 July 2018

1 reference

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Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850700

The spatial and temporal expression of the α2β1 integrin and its ligands, collagen I, collagen IV, and laminin, suggest important roles in mouse mammary morphogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850700

Branching morphogenesis of human mammary epithelial cells in collagen gels.

12 July 2018

1 reference

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Complex patterns of expression suggest extensive roles for the α2β1 integrin in murine development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850700

Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850700

The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850700

The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others

12 July 2018

1 reference

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Decreased expression of integrin adhesive protein receptors in adenocarcinoma of the breast

12 July 2018

1 reference

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Alpha 2 beta 1 integrins from different cell types show different binding specificities

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850700

Distinct determinants on collagen support alpha 2 beta 1 integrin-mediated platelet adhesion and platelet activation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850700

Association of the platelet glycoprotein Ia C807T gene polymorphism with nonfatal myocardial infarction in younger patients.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850700

Analysis of collagen receptors

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964185-5

Collagen-stimulated activation of Syk but not c-Src is severely compromised in human platelets lacking membrane glycoprotein VI

7 January 2021

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964185-5

Glycoprotein VI is a major collagen receptor for platelet activation: it recognizes the platelet-activating quaternary structure of collagen, whereas CD36, glycoprotein IIb/IIIa, and von Willebrand factor do not

7 January 2021

1 reference

12 December 2020

Nucleotide polymorphisms in the alpha2 gene define multiple alleles that are associated with differences in platelet alpha2 beta1 density

1 reference

12 December 2020

The alpha2 gene coding sequence T807/A873 of the platelet collagen receptor integrin alpha2beta1 might be a genetic risk factor for the development of stroke in younger patients

1 reference

12 December 2020

Glycoprotein V-deficient platelets have undiminished thrombin responsiveness and Do not exhibit a Bernard-Soulier phenotype

1 reference

12 December 2020

Association between diabetic retinopathy and genetic variations in alpha2beta1 integrin, a platelet receptor for collagen

1 reference

12 December 2020

Deficiency of platelet membrane glycoprotein Ia associated with a decreased platelet adhesion to subendothelium: a defect in platelet spreading

1 reference

12 December 2020

The alpha 2 beta 1 integrin: a collagen receptor on platelets and other cells

1 reference

12 December 2020

10.1016/S0002-9440(10)64185-5

Identifiers

DOI

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10 August 2017

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10 August 2017

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