Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial (Q35733010)

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scientific article published on 10 June 2015

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English	Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial	scientific article published on 10 June 2015

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 August 2017

Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial (English)

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Europe PubMed Central

PubMed publication ID

10 August 2017

chronic obstructive pulmonary disease

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based on heuristic

inferred from title

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based on heuristic

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Peter J. Barnes

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26058585%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Andrew H Briggs

4

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13 June 2020

Anthony De Soyza

9

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13 June 2020

Kirsty McCormack

14

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13 June 2020

Seonaidh Cotton

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Seonaidh Cotton

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13 June 2020

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Rekha Chaudhuri

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Rekha Chaudhuri

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Henry Chrystyn

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13 June 2020

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Simon Gompertz

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13 June 2020

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John Haughney

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13 June 2020

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David Price

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13 June 2020

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Graham Devereux

1

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13 June 2020

Graham Burns

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13 June 2020

Lisa Davies

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13 June 2020

Shona Fielding

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13 June 2020

Amanda J Lee

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13 June 2020

Alyn Morice

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13 June 2020

John Norrie

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13 June 2020

Anita Sullivan

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13 June 2020

Andrew Wilson

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13 June 2020

Gladys McPherson

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13 June 2020

publication date

10 June 2015

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10 August 2017

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13 June 2020

16

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13 June 2020

267

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13 June 2020

copyright license

Creative Commons Attribution 4.0 International

10 June 2015

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April 2022 Public Data File from Crossref

copyright status

0 references

Treatment effects of low-dose theophylline combined with an inhaled corticosteroid in COPD.

1 reference

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27 July 2018

Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease.

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Targeting the epigenome in the treatment of asthma and chronic obstructive pulmonary disease

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27 July 2018

Effect of theophylline on the rate of moderate to severe exacerbations among patients with chronic obstructive pulmonary disease

1 reference

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27 July 2018

Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression

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27 July 2018

Health-related quality of life is related to COPD disease severity

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27 July 2018

Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper

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27 July 2018

Methylxanthines for exacerbations of chronic obstructive pulmonary disease: meta-analysis of randomised trials

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27 July 2018

Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease

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27 July 2018

Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease

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27 July 2018

Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice

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27 July 2018

Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease

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27 July 2018

EuroQol--a new facility for the measurement of health-related quality of life

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27 July 2018

Modeling Valuations for EuroQol Health States

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27 July 2018

Theophylline kinetics in relation to age: the importance of smoking

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27 July 2018

The accuracy of a pharmacokinetic theophylline predictor using once daily dosing

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27 July 2018

The accuracy and stability of Bayesian theophylline predictions.

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27 July 2018

Dose response relation to oral theophylline in severe chronic obstructive airways disease

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27 July 2018

Bayesian derived predictions for twice daily theophylline under outpatient conditions and an assessment of optimal sampling times

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27 July 2018

Effect of smoking on theophylline disposition

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27 July 2018

The influence of cigarette smoking and sex on theophylline disposition

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27 July 2018

Theophylline disposition in acutely ill hospitalized patients. The effect of smoking, heart failure, severe airway obstruction, and pneumonia

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27 July 2018

Enhanced biotransformation of theophylline in marihuana and tobacco smokers

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27 July 2018

Role of tobacco smoking in pharmacokinetics

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27 July 2018

The COPD assessment test (CAT): response to pulmonary rehabilitation. A multicentre, prospective study

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25 September 2018

Predictive accuracy of patient-reported exacerbation frequency in COPD.

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25 September 2018

Development and first validation of the COPD Assessment Test

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25 September 2018

Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice

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25 September 2018

Low-dose theophylline enhances the anti-inflammatory effects of steroids during exacerbations of COPD.

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25 September 2018

Comparison of ideal body weight equations and published height-weight tables with body mass index tables for healthy adults in the United States

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25 September 2018

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25 September 2018

Decreased histone deacetylase activity in chronic obstructive pulmonary disease.

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25 September 2018

Exacerbations and time spent outdoors in chronic obstructive pulmonary disease

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25 September 2018

A prospective clinical study of theophylline safety in 3810 elderly with asthma or COPD.

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25 September 2018

Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages.

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A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression.

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25 September 2018

Low-dose theophylline reduces eosinophilic inflammation but not exhaled nitric oxide in mild asthma.

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25 September 2018

Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.

1 reference

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25 September 2018

Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4465017

25 September 2018

Chronic obstructive pulmonary disease stage and health-related quality of life. The Quality of Life of Chronic Obstructive Pulmonary Disease Study Group.

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25 September 2018

Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease

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21 January 2018

Anti-inflammatory effects of low-dose oral theophylline in atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/26058585

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of High Dose Inhaled Steroid on Cells, Cytokines, and Proteases in Induced Sputum in Chronic Obstructive Pulmonary Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26058585

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of theophylline after a single intravenous infusion of aminophylline

1 reference

https://pubmed.ncbi.nlm.nih.gov/26058585

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S13063-015-0782-2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26058585%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26058585%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26058585%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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