Natural IgM in immune equilibrium and harnessing their therapeutic potential (Q35694606)

9 August 2017

title

Natural IgM in immune equilibrium and harnessing their therapeutic potential (English)

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9 August 2017

Srini V Kaveri

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Jagadeesh Bayry

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Gregg J Silverman

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9 August 2017

language of work or name

English

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publication date

1 February 2012

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9 August 2017

published in

Journal of Immunology

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9 August 2017

volume

188

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9 August 2017

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9 August 2017

page(s)

939-945

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CD22 serves as a receptor for soluble IgM.

9 August 2017

cites work

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Identity of the elusive IgM Fc receptor (FcmuR) in humans

12 July 2018

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12 July 2018

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Adult BM generates CD5+ B1 cells containing abundant N-region additions

12 July 2018

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12 July 2018

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Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis

12 July 2018

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Novel cellular and molecular mechanisms of induction of immune responses by aluminum adjuvants

12 July 2018

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IgM antibodies to apoptosis-associated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells

12 July 2018

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Characterization of the antibody response against NeuGcGM3 ganglioside elicited in non-small cell lung cancer patients immunized with an anti-idiotype antibody

12 July 2018

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Nature and functions of autoantibodies

12 July 2018

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12 July 2018

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A new tumor-specific variant of GRP78 as target for antibody-based therapy

12 July 2018

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12 July 2018

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The broad antibacterial activity of the natural antibody repertoire is due to polyreactive antibodies

12 July 2018

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Natural antibody and complement mediate neutralization of influenza virus in the absence of prior immunity

12 July 2018

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12 July 2018

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IgM-enriched human intravenous immunoglobulin suppresses T lymphocyte functions in vitro and delays the activation of T lymphocytes in hu-SCID mice.

12 July 2018

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12 July 2018

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12 July 2018

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Transcriptional suppression of interleukin-12 gene expression following phagocytosis of apoptotic cells

12 July 2018

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12 July 2018

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The role of complement in the development of systemic lupus erythematosus

12 July 2018

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Natural human polyreactive IgM induce apoptosis of lymphoid cell lines and human peripheral blood mononuclear cells.

12 July 2018

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Immunoglobulin M-enriched intravenous immunoglobulin inhibits classical pathway complement activation, but not bactericidal activity of human serum.

12 July 2018

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Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses.

12 July 2018

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Natural autoantibodies as tools to predict the outcome of immune response?

12 July 2018

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CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity

12 July 2018

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Complement. First of two parts

12 July 2018

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B cell development pathways

12 July 2018

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Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes

12 July 2018

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Generation, expansion, migration and activation of mouse B1 cells

12 July 2018

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Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity

12 July 2018

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Human monoclonal antibodies reactive to oligodendrocytes promote remyelination in a model of multiple sclerosis

12 July 2018

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Regulation of antibody responses via antibodies, complement, and Fc receptors

12 July 2018

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Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies.

12 July 2018

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Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM.

12 July 2018

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Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition

12 July 2018

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Abnormal transcription factor induction through the surface immunoglobulin M receptor of B-1 lymphocytes

12 July 2018

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Complement activation is required for IgM-mediated enhancement of the antibody response

12 July 2018

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12 July 2018

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B1a B lymphocytes are atheroprotective by secreting natural IgM that increases IgM deposits and reduces necrotic cores in atherosclerotic lesions

12 July 2018

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Complement and natural antibody are required in the long-term memory response to influenza virus

25 September 2018

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Natural antibodies against phosphorylcholine as potential protective factors in SLE.

25 September 2018

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CpG drives human transitional B cells to terminal differentiation and production of natural antibodies

25 September 2018

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Effects of IGM-enriched solution on polymorphonuclear neutrophil function, bacterial clearance, and lung histology in endotoxemia.

25 September 2018

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Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular events

25 September 2018

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Restoration of natural IgM production from liver B cells by exogenous IL-18 improves the survival of burn-injured mice infected with Pseudomonas aeruginosa.

25 September 2018

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Antigenic properties of peptide mimotopes of HIV-1-associated carbohydrate antigens.

25 September 2018

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Autoantibodies to OxLDL fail to alter the clearance of injected OxLDL in apolipoprotein E-deficient mice

25 September 2018

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Immunoglobulin M Type of Autoantibodies to Oxidized Low-Density Lipoprotein Has an Inverse Relation to Carotid Artery Atherosclerosis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266110

The autoreactivity of anti-phosphorylcholine antibodies for atherosclerosis-associated neo-antigens and apoptotic cells

25 September 2018

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Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL.

25 September 2018

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Anti-endotoxin human monoclonal antibody A6H4C5 (HA-1A) utilizes the VH4.21 gene

25 September 2018

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De novo development and self-replenishment of B cells.

25 September 2018

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Predominant role of IgM-dependent activation of the classical pathway in the clearance of dying cells by murine bone marrow-derived macrophagesin vitro

25 September 2018

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Phosphorylcholine-targeting immunization reduces atherosclerosis

15 November 2018

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12 December 2020

IgM anti-β2 glycoprotein I is protective against lupus nephritis and renal damage in systemic lupus erythematosus

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12 December 2020

Cutting Edge: Selection of B Lymphocyte Subsets Is Regulated by Natural IgM

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12 December 2020

Production of immunoglobulin isotypes by Ly-1+ B cells in viable motheaten and normal mice

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12 December 2020

Interleukin-18 protects splenectomized mice from lethal Streptococcus pneumoniae sepsis independent of interferon-gamma by inducing IgM production

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12 December 2020

The human IgM antibody SAM-6 induces tumor-specific apoptosis with oxidized low-density lipoprotein

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12 December 2020

Peritoneal CD5+ B-1 cells have signaling properties similar to tolerant B cells

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12 December 2020

Immunoglobulin-bearing B cells reconstitute and maintain the murine Ly-1 B cell lineage

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12 December 2020

Cytotoxic natural antibodies against human tumours: an option for anti-cancer immunotherapy?

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12 December 2020

Natural IgM Is Required for Suppression of Inflammatory Arthritis by Apoptotic Cells

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12 December 2020

Immunoglobulin M-enriched human intravenous immunoglobulin prevents complement activation in vitro and in vivo in a rat model of acute inflammation

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12 December 2020

Human natural immunoglobulin M antibodies induce apoptosis of human neuroblastoma cells by binding to a Mr 260,000 antigen

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12 December 2020

Control of early viral and bacterial distribution and disease by natural antibodies

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12 December 2020

Normal human immunoglobulin suppresses experimental myasthenia gravis in SCID mice

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12 December 2020

Human antibodies accelerate the rate of remyelination following lysolecithin-induced demyelination in mice

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12 December 2020

Expression and control of the natural autoreactive IgG repertoire in normal human serum

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12 December 2020

Pooled normal human polyspecific IgM contains neutralizing anti-idiotypes to IgG autoantibodies of autoimmune patients and protects from experimental autoimmune disease

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12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1102107

1 reference

9 August 2017

1 reference

9 August 2017

1 reference