Anergic CD8+ T lymphocytes have impaired NF-κB activation with defects in p65 phosphorylation and acetylation (Q35685458)

9 August 2017

title

Anergic CD8+ T lymphocytes have impaired NF-κB activation with defects in p65 phosphorylation and acetylation (English)

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9 August 2017

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Paúl E Clavijo

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9 August 2017

Kenneth A Frauwirth

series ordinal

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9 August 2017

language of work or name

English

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publication date

28 December 2011

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9 August 2017

published in

Journal of Immunology

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9 August 2017

volume

188

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9 August 2017

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9 August 2017

page(s)

1213-1221

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Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

9 August 2017

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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In vivo anergized CD4+ T cells express perturbed AP-1 and NF-kappa B transcription factors

27 July 2018

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27 July 2018

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27 July 2018

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Activation of NF-kappa B in vivo is regulated by multiple phosphorylations

27 July 2018

1 reference

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I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

27 July 2018

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The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells.

27 July 2018

1 reference

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Reciprocal NFAT1 and NFAT2 nuclear localization in CD8+ anergic T cells is regulated by suboptimal calcium signaling.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262885

Insufficient p65 phosphorylation at S536 specifically contributes to the lack of NF-kappaB activation and transformation in resistant JB6 cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262885

Protein kinase C beta is dispensable for TCR-signaling

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262885

Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262885

IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262885

Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262885

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262885

CTLA-4 is not required for induction of CD8(+) T cell anergy in vivo.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262885

Tolerant CD8 T cells induced by multiple injections of peptide antigen show impaired TCR signaling and altered proliferative responses in vitro and in vivo

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262885

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

25 September 2018

1 reference

12 December 2020

NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development

1 reference

12 December 2020

Regulation of activator protein-1 and NF-kappa B in CD8+ T cells exposed to peripheral self-antigens

1 reference

12 December 2020

Bcl-3 and NFkappaB p50-p50 homodimers act as transcriptional repressors in tolerant CD4+ T cells

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12 December 2020

PKCdelta is involved in signal attenuation in CD3+ T cells

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12 December 2020

Adaptive tolerance and clonal anergy are distinct biochemical states

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Defective IgG2a/2b class switching in PKC alpha-/- mice

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Differential regulation of p65 and c-Rel NF-κB transactivating activity by Cot, protein kinase C ζ and NIK protein kinases in CD3/CD28 activated T cells

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Identifiers

DOI

10.4049/JIMMUNOL.1100793

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9 August 2017

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9 August 2017

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