The biology of cytomegalovirus drug resistance (Q35684511)

9 August 2017

title

The biology of cytomegalovirus drug resistance (English)

1 reference

9 August 2017

Morgan Hakki

1 reference

9 August 2017

Sunwen Chou

series ordinal

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9 August 2017

publication date

1 December 2011

1 reference

Current Opinion in Infectious Diseases

9 August 2017

published in

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

605-611

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Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet

9 August 2017

cites work

1 reference

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12 July 2018

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12 July 2018

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Maribavir prophylaxis for prevention of cytomegalovirus disease in recipients of allogeneic stem-cell transplants: a phase 3, double-blind, placebo-controlled, randomised trial

12 July 2018

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Mass spectrometry-based comparative sequencing to detect ganciclovir resistance in the UL97 gene of human cytomegalovirus.

12 July 2018

1 reference

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Antiviral inhibition targeting the HCMV kinase pUL97 requires pUL27-dependent degradation of Tip60 acetyltransferase and cell-cycle arrest

12 July 2018

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Phenotypic diversity of cytomegalovirus DNA polymerase gene variants observed after antiviral therapy

12 July 2018

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12 July 2018

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Cytomegalovirus UL97 Mutations Affecting Cyclopropavir and Ganciclovir Susceptibility

12 July 2018

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Recombinant Phenotyping of Cytomegalovirus Sequence Variants Detected After 200 or 100 Days of Valganciclovir Prophylaxis

12 July 2018

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Drug-resistant cytomegalovirus in transplant recipients: a French cohort study

12 July 2018

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Antiviral Drug Resistance of Human Cytomegalovirus

12 July 2018

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Improved detection of mutated human cytomegalovirus UL97 by pyrosequencing

12 July 2018

1 reference

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Differentiation between Polymorphisms and Resistance-Associated Mutations in Human Cytomegalovirus DNA Polymerase

12 July 2018

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Oral maribavir for treatment of refractory or resistant cytomegalovirus infections in transplant recipients

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Stereoselective phosphorylation of cyclopropavir by pUL97 and competitive inhibition by maribavir.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Deep sequencing reveals highly complex dynamics of human cytomegalovirus genotypes in transplant patients over time

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Recombinant phenotyping of cytomegalovirus UL97 kinase sequence variants for ganciclovir resistance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

International consensus guidelines on the management of cytomegalovirus in solid organ transplantation

12 July 2018

1 reference

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In vitro and in vivo activities of the novel anticytomegalovirus compound AIC246.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Function of human cytomegalovirus UL97 kinase in viral infection and its inhibition by maribavir.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Diverse cytomegalovirus UL27 mutations adapt to loss of viral UL97 kinase activity under maribavir

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Incidence and outcomes of ganciclovir-resistant cytomegalovirus infections in 1244 kidney transplant recipients.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Genotypic characterization of human cytomegalovirus UL97 phosphotransferase natural polymorphism in the era of ganciclovir and maribavir

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Diversity of antiviral-resistant human cytomegalovirus in heart and lung transplant recipients

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Contrasting effects on ganciclovir susceptibility and replicative capacity of two mutations at codon 466 of the human cytomegalovirus UL97 gene

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Extended valganciclovir prophylaxis to prevent cytomegalovirus after lung transplantation: a randomized, controlled trial

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Virologic characterization of multidrug-resistant cytomegalovirus infection in 2 transplant recipients treated with maribavir

25 September 2018

1 reference

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The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Preemptive versus sequential prophylactic-preemptive treatment regimens for cytomegalovirus in renal transplantation: comparison of treatment failure and antiviral resistance

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Incidence and characterization of cytomegalovirus resistance mutations among pediatric solid organ transplant patients who received valganciclovir prophylaxis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Cytomegalovirus resistance in solid organ transplant recipients treated with intravenous ganciclovir or oral valganciclovir

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Effect of cell culture conditions on the anticytomegalovirus activity of maribavir

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Crystal structure of the herpes simplex virus 1 DNA polymerase

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262590

Cytomegalovirus UL97 kinase mutations that confer maribavir resistance

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22001948

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

First Report of Successful Treatment of Multidrug-Resistant Cytomegalovirus Disease with the Novel Anti-CMV Compound AIC246

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22001948

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Why did maribavir fail in stem-cell transplants?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22001948

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1097/QCO.0B013E32834CFB58

1 reference

9 August 2017

1 reference

9 August 2017

1 reference