A novel pathway to the manifestations of metabolic syndrome (Q35674454)

9 August 2017

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title

A novel pathway to the manifestations of metabolic syndrome (English)

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9 August 2017

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Ahmed H Kissebah

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9 August 2017

author name string

Gabriele E Sonnenberg

series ordinal

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9 August 2017

Glenn R Krakower

series ordinal

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9 August 2017

publication date

1 February 2004

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9 August 2017

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

180-186

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The acute phase protein response in patients receiving subcutaneous IL-6.

9 August 2017

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Effects of TNF-alpha on glucose metabolism and lipolysis in adipose tissue and isolated fat-cell preparations

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The role of growth hormone/insulin-like growth factors in adipocyte differentiation

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Tumor necrosis factor-alpha stimulates cell proliferation in adipose tissue-derived stromal-vascular cell culture: promotion of adipose tissue expansion by paracrine growth factors

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IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

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Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

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Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex.

21 January 2018

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Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins

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Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

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Adiponectin: systemic contributor to insulin sensitivity

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Adiponectin and protection against type 2 diabetes mellitus

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

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Increased beta -oxidation but no insulin resistance or glucose intolerance in mice lacking adiponectin

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Young men with high-normal blood pressure have lower serum adiponectin, smaller LDL size, and higher elevated heart rate than those with optimal blood pressure

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Decreased plasma adiponectin concentrations in women with dyslipidemia

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Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin

21 January 2018

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Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell

21 January 2018

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Disruption of adiponectin causes insulin resistance and neointimal formation

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Influences of ionomycin, dibutyryl-cycloAMP and tumour necrosis factor-alpha on intracellular amount and secretion of apM1 in differentiating primary human preadipocytes

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PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein

21 January 2018

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The metabolic effects of tumor necrosis factor and other cytokines

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Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes

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Association between adiponectin and mediators of inflammation in obese women.

21 January 2018

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Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway

21 January 2018

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NF-kappaB activation and inhibition: a review

21 January 2018

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Inflammation and atherosclerosis

21 January 2018

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Humoral markers of inflammation and endothelial dysfunction in relation to adiposity and in vivo insulin action in Pima Indians

21 January 2018

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Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes

21 January 2018

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Improvement of the mitochondrial antioxidant defense status prevents cytokine-induced nuclear factor-kappaB activation in insulin-producing cells.

21 January 2018

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Endothelial function in the post-prandial state

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Postprandial endothelial activation in healthy subjects and in type 2 diabetic patients: role of fat and carbohydrate meals.

21 January 2018

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The relationship between plasma glucose and insulin responses to oral glucose, LDL oxidation, and soluble intercellular adhesion molecule-1 in healthy volunteers.

21 January 2018

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Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease

21 January 2018

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Circulating oxidized low-density lipoprotein (LDL) is associated with risk factors of the metabolic syndrome and LDL size in clinically healthy 58-year-old men (AIR study).

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Beneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress

21 January 2018

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NF-kappa B activation in endothelial cells treated with oxidized high-density lipoprotein

21 January 2018

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Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension

21 January 2018

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Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance

21 January 2018

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Circulating E-selectin, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 in men with coronary artery disease assessed by angiography and disturbances of carbohydrate metabolism

21 January 2018

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Plasma profiles of peripheral monocyte-related inflammatory markers in patients with arterial hypertension. Correlations with plasma endothelin-1.

21 January 2018

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Low insulin sensitivity measured by both quantitative insulin sensitivity check index and homeostasis model assessment method as a risk factor of increased intima-media thickness of the carotid artery

21 January 2018

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Effect of elevated triglyceride levels on endothelium-dependent vasodilation in patients with hypercholesterolemia

21 January 2018

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Endotheliopathy precedes type 2 diabetes.

21 January 2018

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Interleukin-6 and the acute phase response

21 January 2018

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Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue.

21 January 2018

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C-reactive protein-mediated low density lipoprotein uptake by macrophages: implications for atherosclerosis

21 January 2018

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Elevated plasma endothelin in patients with diabetes mellitus

21 January 2018

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The impact of serum lipid levels on circulating soluble adhesion molecules in childhood

21 January 2018

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Soluble intercellular adhesion molecule-1, soluble vascular adhesion molecule-1, and the development of symptomatic peripheral arterial disease in men.

21 January 2018

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Identifying the links between obesity, insulin resistance and beta-cell function: potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetes

21 January 2018

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The expression of TNF alpha by human muscle. Relationship to insulin resistance

21 January 2018

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NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X

21 January 2018

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C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?

21 January 2018

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Obesity, cytokines and endothelial dysfunction: a link for the raised cardiovascular risk associated with visceral obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Inflammatory status and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Minireview: Adiposity, Inflammation, and Atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Quantitative trait loci on chromosomes 3 and 17 influence phenotypes of the metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2004.24

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

21 January 2018

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Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

21 January 2018

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Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2004.24

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

The role of PPARs in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Resistin and adiponectin expression in visceral fat of obese rats: effect of weight loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Elevated production of interleukin-6 is associated with a lower incidence of disease-related ischemic events in patients with giant-cell arteritis: angiogenic activity of interleukin-6 as a potential protective mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

The Genetic Basis of Plasma Variation in Adiponectin, a Global Endophenotype for Obesity and the Metabolic Syndrome

21 January 2018

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https://api.crossref.org/works/10.1038%2FOBY.2004.24

Elevated C-reactive protein levels in overweight and obese adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Effects of tumour necrosis factor alpha (TNF alpha) on glucose transport and lipid metabolism of newly-differentiated human fat cells in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Adipose tissue as an endocrine and paracrine organ

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Weight Reduction Increases Plasma Levels of an Adipose-Derived Anti-Inflammatory Protein, Adiponectin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Decreased plasma adiponectin concentration in patients with essential hypertension

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

The metabolic syndrome is associated with elevated circulating C-reactive protein in healthy reference range, a systemic low-grade inflammatory state

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Direct proinflammatory effect of C-reactive protein on human endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Interrelationship of changes in islet nicotine adeninedinucleotide, insulin secretion, and cell viability induced by interleukin-1 beta

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Interferon-gamma: pleiotropic effects on a rat pancreatic beta cell line

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

The central roles of obesity-associated dyslipidaemia, endothelial activation and cytokines in the Metabolic Syndrome—an analysis by structural equation modelling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Association of hypoadiponectinemia with coronary artery disease in men

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

A novel mechanism for the inhibition of NF-kappaB activation in vascular endothelial cells by natural antioxidants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FOBY.2004.24

31 March 2020

Identifiers

DOI

10.1038/OBY.2004.24

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9 August 2017

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