The mediator complex (Q35669882)

9 August 2017

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title

The mediator complex (English)

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9 August 2017

Stefan Björklund

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9 August 2017

Claes M Gustafsson

series ordinal

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9 August 2017

publication date

1 January 2004

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Advances in Protein Chemistry

9 August 2017

published in

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9 August 2017

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9 August 2017

page(s)

43-65

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What does 'chromatin remodeling' mean?

9 August 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Conserved structures of mediator and RNA polymerase II holoenzyme

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

The Med1 subunit of the yeast mediator complex is involved in both transcriptional activation and repression.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Functional interactions within yeast mediator and evidence of differential subunit modifications

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Three subunits of the RNA polymerase II mediator complex are involved in glucose repression.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Regulation of nuclear genes encoding mitochondrial proteins in Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

A mammalian SRB protein associated with an RNA polymerase II holoenzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Med8, a subunit of the mediator CTD complex of RNA polymerase II, directly binds to regulatory elements of SUC2 and HXK2 genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Cdk1 Triggers Association of RNA Polymerase to Cell Cycle Promoters Only after Recruitment of the Mediator by SBF

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Structural organization of yeast and mammalian mediator complexes

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

A mediator required for activation of RNA polymerase II transcription in vitro

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Srb7p is essential for the activation of a subset of genes

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Dissecting the regulatory circuitry of a eukaryotic genome

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Involvement of the SIN4 global transcriptional regulator in the chromatin structure of Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

A novel mediator between activator proteins and the RNA polymerase II transcription apparatus

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

An activator target in the RNA polymerase II holoenzyme

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

An RNA polymerase II holoenzyme responsive to activators

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Requirement for a functional interaction between mediator components Med6 and Srb4 in RNA polymerase II transcription

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

A Transcriptional Mediator Protein That Is Required for Activation of Many RNA Polymerase II Promoters and Is Conserved from Yeast to Humans

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

An activator binding module of yeast RNA polymerase II holoenzyme

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Nuclear receptor cofactors as chromatin remodelers

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

A kinase-cyclin pair in the RNA polymerase II holoenzyme.

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Mediator-nucleosome interaction

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

RNA polymerase II holoenzymes and subcomplexes.

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Mediator protein mutations that selectively abolish activated transcription

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Mediator of Transcriptional Regulation

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Composite co-activator ARC mediates chromatin-directed transcriptional activation

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Transcription activation via enhanced preinitiation complex assembly in a human cell-free system lacking TAFIIs

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

In vivo requirement of activator-specific binding targets of mediator

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Association of an X-chromosome dodecamer insertional variant allele with mental retardation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

The ROX3 gene encodes an essential nuclear protein involved in CYC7 gene expression in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Structure and molecular analysis of RGR1, a gene required for glucose repression of Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Functional connections between mediator components and general transcription factors of Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Yeast GAL11 protein is a distinctive type transcription factor that enhances basal transcription in vitro

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

The yeast GAL11 protein binds to the transcription factor IIE through GAL11 regions essential for its in vivo function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Yeast TAF(II)145 functions as a core promoter selectivity factor, not a general coactivator

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase II

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Purification and characterization of RNA polymerase II holoenzyme from Schizosaccharomyces pombe

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Analysis of Schizosaccharomyces pombe mediator reveals a set of essential subunits conserved between yeast and metazoan cells

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

The yeast GAL11 protein is involved in regulation of the structure and the position effect of telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

GAL11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Evidence for a mediator cycle at the initiation of transcription.

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Nuclear proteins Nut1p and Nut2p cooperate to negatively regulate a Swi4p-dependent lacZ reporter gene in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast.

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

General requirement for RNA polymerase II holoenzymes in vivo

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Repression by SSN6-TUP1 is directed by MIG1, a repressor/activator protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Chromatin remodeling and transcriptional activation: the cast (in order of appearance).

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Characterization of mediator complexes from HeLa cell nuclear extract

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

CSE1 and CSE2, two new genes required for accurate mitotic chromosome segregation in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

SPT13 (GAL11) of Saccharomyces cerevisiae negatively regulates activity of the MCM1 transcription factor in Ty1 elements

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

A transcription reinitiation intermediate that is stabilized by activator

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor

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https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

Deletion of PBP/PPARBP, the gene for nuclear receptor coactivator peroxisome proliferator-activated receptor-binding protein, results in embryonic lethality

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

The Schizosaccharomyces pombe sep15+ gene encodes a protein homologous to the Med8 subunit of the Saccharomyces cerevisiae transcriptional mediator complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2804%2967002-1

7 January 2021

10.1016/S0065-3233(04)67002-1

Identifiers

DOI

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9 August 2017

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