Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling (Q35638953)

9 August 2017

title

Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling (English)

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9 August 2017

Brian K Kobilka

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9 August 2017

Aashish Manglik

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9 August 2017

Wayne L Hubbell

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9 August 2017

Tong Sun Kobilka

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9 August 2017

Tae Hun Kim

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9 August 2017

Matthieu Masureel

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9 August 2017

Christian Altenbach

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9 August 2017

Zhongyu Yang

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9 August 2017

Daniel Hilger

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9 August 2017

Michael T Lerch

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9 August 2017

Foon Sun Thian

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9 August 2017

R Scott Prosser

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9 August 2017

language of work or name

English

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publication date

14 May 2015

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9 August 2017

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9 August 2017

volume

161

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9 August 2017

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9 August 2017

page(s)

1101-1111

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The dynamic process of β(2)-adrenergic receptor activation

9 August 2017

cites work

1 reference

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27 July 2018

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Efficacy of the β₂-adrenergic receptor is determined by conformational equilibrium in the transmembrane region

27 July 2018

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27 July 2018

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Activation mechanism of the β2-adrenergic receptor

27 July 2018

1 reference

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Crystal structure of the β2 adrenergic receptor-Gs protein complex

27 July 2018

1 reference

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Two distinct conformations of helix 6 observed in antagonist-bound structures of a 1-adrenergic receptor

27 July 2018

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Crystal structure of metarhodopsin II

27 July 2018

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The structural basis of agonist-induced activation in constitutively active rhodopsin

27 July 2018

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Structure and function of an irreversible agonist-β(2) adrenoceptor complex

27 July 2018

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Structure of a nanobody-stabilized active state of the β(2) adrenoceptor

27 July 2018

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27 July 2018

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Identification of two distinct inactive conformations of the beta2-adrenergic receptor reconciles structural and biochemical observations

27 July 2018

1 reference

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High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

27 July 2018

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Sequence of late molecular events in the activation of rhodopsin

27 July 2018

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Dynamic personalities of proteins

27 July 2018

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

27 July 2018

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GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

27 July 2018

1 reference

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Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

27 July 2018

1 reference

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The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors

27 July 2018

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Sequential binding of agonists to the beta2 adrenoceptor. Kinetic evidence for intermediate conformational states

27 July 2018

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NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR.

27 July 2018

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Amino and carboxyl terminal modifications to facilitate the production and purification of a G protein-coupled receptor

27 July 2018

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Two different forms of metarhodopsin II: Schiff base deprotonation precedes proton uptake and signaling state

27 July 2018

1 reference

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Kinetics and mechanism of G protein-coupled receptor activation.

27 July 2018

1 reference

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Tracing an allosteric pathway regulating the activity of the HslV protease

25 September 2018

1 reference

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NMR paves the way for atomic level descriptions of sparsely populated, transiently formed biomolecular conformers

25 September 2018

1 reference

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25 September 2018

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Structure and activation of the visual pigment rhodopsin

25 September 2018

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NMR spectroscopy brings invisible protein states into focus

25 September 2018

1 reference

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Activation of rhodopsin: new insights from structural and biochemical studies

25 September 2018

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Agonist-induced conformational changes at the cytoplasmic side of transmembrane segment 6 in the beta 2 adrenergic receptor mapped by site-selective fluorescent labeling.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441853

Temperature and pH dependence of the metarhodopsin I-metarhodopsin II kinetics and equilibria in bovine rod disk membrane suspensions.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441853

Modulation of the metarhodopsin I/metarhodopsin II equilibrium of bovine rhodopsin by ionic strength--evidence for a surface-charge effect

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25981665

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Lipid headgroup and acyl chain composition modulate the MI-MII equilibrium of rhodopsin in recombinant membranes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25981665

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2015.04.043

1 reference

9 August 2017

1 reference

9 August 2017

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