Attenuation of herpes simplex virus neurovirulence with picornavirus cis-acting genetic elements (Q35635064)

9 August 2017

title

Attenuation of herpes simplex virus neurovirulence with picornavirus cis-acting genetic elements (English)

1 reference

9 August 2017

Stephanie A Campbell

1 reference

9 August 2017

Matthew Mulvey

series ordinal

1 reference

9 August 2017

Ian Mohr

series ordinal

1 reference

9 August 2017

Matthias Gromeier

series ordinal

1 reference

9 August 2017

language of work or name

English

0 references

publication date

1 November 2006

1 reference

9 August 2017

1 reference

9 August 2017

1 reference

9 August 2017

1 reference

9 August 2017

page(s)

791-799

1 reference

The double-stranded RNA binding protein 76:NF45 heterodimer inhibits translation initiation at the rhinovirus type 2 internal ribosome entry site

9 August 2017

cites work

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27 July 2018

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27 July 2018

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27 July 2018

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Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1

27 July 2018

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27 July 2018

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Enhanced therapeutic efficacy of G207 for the treatment of glioma through Musashi1 promoter retargeting of gamma34.5-mediated virulence.

27 July 2018

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mRNA decay during herpes simplex virus (HSV) infections: protein-protein interactions involving the HSV virion host shutoff protein and translation factors eIF4H and eIF4A.

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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Activity of a type 1 picornavirus internal ribosomal entry site is determined by sequences within the 3' nontranslated region

27 July 2018

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Regulation of eIF2alpha phosphorylation by different functions that act during discrete phases in the herpes simplex virus type 1 life cycle

27 July 2018

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mRNA decay during herpesvirus infections: interaction between a putative viral nuclease and a cellular translation factor

27 July 2018

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Enhanced antitumor efficacy of a herpes simplex virus mutant isolated by genetic selection in cancer cells

27 July 2018

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A herpes simplex virus type 1 gamma34.5 second-site suppressor mutant that exhibits enhanced growth in cultured glioblastoma cells is severely attenuated in animals

27 July 2018

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Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial

27 July 2018

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Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma

27 July 2018

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27 July 2018

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Dual stem loops within the poliovirus internal ribosomal entry site control neurovirulence

27 July 2018

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27 July 2018

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The range and distribution of murine central nervous system cells infected with the gamma(1)34.5- mutant of herpes simplex virus 1.

27 July 2018

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The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

27 July 2018

1 reference

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A herpesvirus genetic element which affects translation in the absence of the viral GADD34 function

27 July 2018

1 reference

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Herpes simplex virus VP16 rescues viral mRNA from destruction by the virion host shutoff function

27 July 2018

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Internal ribosomal entry site substitution eliminates neurovirulence in intergeneric poliovirus recombinants

27 July 2018

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La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate

27 July 2018

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ICP34.5 mutants of herpes simplex virus type 1 strain 17syn+ are attenuated for neurovirulence in mice and for replication in confluent primary mouse embryo cell cultures

27 July 2018

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Isolation, Characterization, and use of Stem Cells from the CNS

27 July 2018

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27 July 2018

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The terminal a sequence of the herpes simplex virus genome contains the promoter of a gene located in the repeat sequences of the L component.

27 July 2018

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Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

27 July 2018

1 reference

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A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation

27 July 2018

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Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily

27 July 2018

1 reference

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Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

The gamma 1(34.5) gene of herpes simplex virus 1 precludes neuroblastoma cells from triggering total shutoff of protein synthesis characteristic of programed cell death in neuronal cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

Cell-type-specific repression of internal ribosome entry site activity by double-stranded RNA-binding protein 76.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to Polysomes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

The vhs1 mutant form of herpes simplex virus virion host shutoff protein retains significant internal ribosome entry site-directed RNA cleavage activity.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation of intracerebral injection in nonhuman primates.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

Cleavage of poly(A)-binding protein by enterovirus proteases concurrent with inhibition of translation in vitro.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

A neuroattenuated ICP34.5-deficient herpes simplex virus type 1 replicates in ependymal cells of the murine central nervous system

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

Evaluation of genetically engineered herpes simplex viruses as oncolytic agents for human malignant brain tumors.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of her

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797477

Definition of an efficient synthetic poly(A) site

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17079296

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A virus with a mutation in the ICP4-binding site in the L/ST promoter of herpes simplex virus type 1, but not a virus with a mutation in open reading frame P, exhibits cell-type-specific expression of gamma(1)34.5 transcripts and latency-associated

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17079296

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17079296

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.00714-06

1 reference

9 August 2017

1 reference

9 August 2017

1 reference