Cortistatin is not a somatostatin analogue but stimulates prolactin release and inhibits GH and ACTH in a gender-dependent fashion: potential role of ghrelin. (Q35590855)

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scientific article published on 4 October 2011

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English	Cortistatin is not a somatostatin analogue but stimulates prolactin release and inhibits GH and ACTH in a gender-dependent fashion: potential role of ghrelin.	scientific article published on 4 October 2011

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14 February 2020

Cortistatin is not a somatostatin analogue but stimulates prolactin release and inhibits GH and ACTH in a gender-dependent fashion: potential role of ghrelin (English)

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14 February 2020

José Córdoba-Chacón

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Manuel D. Gahete

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14 February 2020

Francisco Gracia-Navarro

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Rhonda D Kineman

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Justo P. Castaño

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Ana I Pozo-Salas

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Ana I Pozo-Salas

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Antonio J Martínez-Fuentes

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4 October 2011

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14 February 2020

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14 February 2020

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14 February 2020

Does the pituitary somatotrope play a primary role in regulating GH output in metabolic extremes?

1 reference

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27 July 2018

Metabolic impact of adult-onset, isolated, growth hormone deficiency (AOiGHD) due to destruction of pituitary somatotropes

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Neuropeptides as therapeutic approach to autoimmune diseases.

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27 July 2018

Somatostatin and its receptors from fish to mammals.

1 reference

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27 July 2018

Unraveling the role of the ghrelin gene peptides in the endocrine pancreas.

1 reference

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27 July 2018

Identification and characterization of new functional truncated variants of somatostatin receptor subtype 5 in rodents

1 reference

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27 July 2018

Cortistatin and pituitary hormone secretion in rat

1 reference

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27 July 2018

Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function

1 reference

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27 July 2018

Cortistatin--functions in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Endocrine actions of cortistatin: in vivo studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Role of endogenous somatostatin in regulating GH output under basal conditions and in response to metabolic extremes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Pharmacological profile of somatostatin and cortistatin receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Dimerization of G protein-coupled receptors: new avenues for somatostatin receptor signalling, control and functioning

1 reference

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27 July 2018

Are somatostatin and cortistatin two siblings in regulating endocrine secretions? In vitro work ahead

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

What can we learn from rodents about prolactin in humans?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Emergence of cortistatin as a new immunomodulatory factor with therapeutic potential in immune disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Brain-gut communication: cortistatin, somatostatin and ghrelin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Cortistatin: not just another somatostatin analog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Cortistatin mimics somatostatin by inducing a dual, dose-dependent stimulatory and inhibitory effect on growth hormone secretion in somatotropes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Cortistatin inhibits growth hormone release from human fetal and adenoma pituitary cells and prolactin secretion from cultured prolactinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Comparative genomics provides evidence for close evolutionary relationships between the urotensin II and somatostatin gene families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Cortistatin-17 and -14 exert the same endocrine activities as somatostatin in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Growth hormone secretagogues and ghrelin: an update on physiology and clinical relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Endocrine activities of cortistatin-14 and its interaction with GHRH and ghrelin in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Growth hormone-inhibiting activity of cortistatin in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Impairment in motor learning of somatostatin null mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Somatostatin is required for masculinization of growth hormone-regulated hepatic gene expression but not of somatic growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Cortistatin, but not somatostatin, binds to growth hormone secretagogue (GHS) receptors of human pituitary gland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Role of growth hormone and prolactin in the control of reproduction: what are we learning from transgenic and knock-out animals?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Null mutation of the prolactin receptor gene produces a defect in maternal behavior.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

A cortical neuropeptide with neuronal depressant and sleep-modulating properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Participation of voltage-sensitive calcium channels in pituitary hormone release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

27 July 2018

Somatostatin and its receptors contribute in a tissue-specific manner to the sex-dependent metabolic (fed/fasting) control of growth hormone axis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Metabolic regulation of ghrelin O-acyl transferase (GOAT) expression in the mouse hypothalamus, pituitary, and stomach.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Identification and characterization of two novel truncated but functional isoforms of the somatostatin receptor subtype 5 differentially present in pituitary tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

The activation of somatostatinergic receptors by either somatostatin-14 or cortistatin-17 often inhibits ACTH hypersecretion in patients with Cushing's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Gender-dependent role of endogenous somatostatin in regulating growth hormone-axis function in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Evidence that ghrelin is as potent as growth hormone (GH)-releasing hormone (GHRH) in releasing GH from primary pituitary cell cultures of a nonhuman primate (Papio anubis), acting through intracellular signaling pathways distinct from GHRH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Evidence that endogenous SST inhibits ACTH and ghrelin expression by independent pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Direct effect of cortistatin on GH release from cultured pituitary cells in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Cortistatin-17 and somatostatin-14 display the same effects on growth hormone, prolactin, and insulin secretion in patients with acromegaly or prolactinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Distribution pattern of somatostatin and cortistatin mRNA in human central and peripheral tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Programming other hormones that affect insulin

1 reference

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26 September 2018

Lactogenic hormone regulation of maternal behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Cortistatin and somatostatin mRNAs are differentially regulated in response to kainate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Null Mutation of the Prolactin Receptor Gene Produces a Defect in Maternal Behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Effects of the two somatostatin variants somatostatin-14 and [Pro2, Met13]somatostatin-14 on receptor binding, adenylyl cyclase activity and growth hormone release from the frog pituitary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230064

26 September 2018

Somatostatin receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel analogs of ghrelin: physiological and clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel ghrelin analogs with improved affinity for the GH secretagogue receptor stimulate GH and prolactin release from human pituitary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin is produced by and directly activates corticotrope cells from adrenocorticotropin-secreting adenomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971153

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/EN.2011-1542

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21971153%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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14 February 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21971153%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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