p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential (Q35595760)

9 August 2017

title

p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential (English)

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9 August 2017

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G I Topley

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9 August 2017

R Okuyama

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9 August 2017

J G Gonzales

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9 August 2017

C Conti

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9 August 2017

G P Dotto

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9 August 2017

language of work or name

English

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publication date

1 August 1999

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Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

published in

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

9089-9094

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Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

9 August 2017

cites work

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Papillomas at high risk for malignant progression arising both early and late during two-stage carcinogenesis in SENCAR mice.

12 July 2018

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Primary Mouse Keratinocyte Cultures Contain Hair Follicle Progenitor Cells with Multiple Differentiation Potential

12 July 2018

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Evidence that cutaneous carcinogen-initiated epithelial cells from mice are quiescent rather than actively cycling

12 July 2018

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p53, the cellular gatekeeper for growth and division

12 July 2018

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A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis

12 July 2018

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Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development.

12 July 2018

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The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.

12 July 2018

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p21 (WAF1/CIP1) expression is induced in newly nondividing cells in diverse epithelia and during differentiation of the Caco-2 intestinal cell line.

12 July 2018

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Fibroblast-dependent induction of a murine skin lesion with similarity to human common blue nevus.

12 July 2018

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Lineage analysis using retrovirus vectors

12 July 2018

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Upper human hair follicle contains a subpopulation of keratinocytes with superior in vitro proliferative potential.

12 July 2018

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Kalinin is more efficient than laminin in promoting adhesion of primary keratinocytes and some other epithelial cells and has a different requirement for integrin receptors

12 July 2018

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Hair follicle stem cells: characteristics and possible significance.

12 July 2018

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Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation.

12 July 2018

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Ultraviolet Light Induces Expression of p53 and p21 in Human Skin: Effect of Sunscreen and Constitutive p21 Expression in Skin Appendages

12 July 2018

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Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

12 July 2018

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Proliferative potential of different keratinocytes of plucked human hair follicles

12 July 2018

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Stem cells in differentiation and neoplasia

12 July 2018

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Calcium regulation of growth and differentiation of mouse epidermal cells in culture

12 July 2018

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Differentiation-linked leukemogenesis in lymphocytes

12 July 2018

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Induction of papillomas with a high probability of conversion to malignancy

12 July 2018

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Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis

12 July 2018

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

12 July 2018

1 reference

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Selection and extended growth of murine epidermal stem cells in culture

12 July 2018

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Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis

26 September 2018

1 reference

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Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17737

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17737

In vivo regulation of murine hair growth: insights from grafting defined cell populations onto nude mice

26 September 2018

1 reference

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Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9089

Stem cell patterning and fate in human epidermis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.96.16.9089

Location of stem cells of human hair follicles by clonal analysis

21 January 2018

1 reference

12 December 2020

Evidence that initiated keratinocytes clonally expand into multiple existing hair follicles during papilloma histogenesis in SENCAR mouse skin

1 reference

12 December 2020

The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted

1 reference

12 December 2020

Inhibitory function of p21Cip1/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control

1 reference

12 December 2020

Deregulated expression of cell-cycle proteins during premalignant progression in SENCAR mouse skin

1 reference

12 December 2020

Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function

1 reference

12 December 2020

Genetic deletion of p21WAF1 enhances papilloma formation but not malignant conversion in experimental mouse skin carcinogenesis

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.96.16.9089

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9 August 2017

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9 August 2017

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