Inhibition of Polo-like kinase 1 reduces beta-amyloid-induced neuronal cell death in Alzheimer's disease (Q35582357)

9 August 2017

title

Inhibition of Polo-like kinase 1 reduces beta-amyloid-induced neuronal cell death in Alzheimer's disease (English)

1 reference

9 August 2017

0 references

1 reference

Mark Smith

1 reference

9 August 2017

Bing Song

1 reference

9 August 2017

Korbin Davis

1 reference

9 August 2017

Hyoung-gon Lee

1 reference

9 August 2017

Xiaoqi Liu

1 reference

9 August 2017

X. Shawn Liu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21931181

12 December 2024

Mark Smith

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21931181

12 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21931181

12 December 2024

publication date

1 September 2011

1 reference

9 August 2017

September 2011

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21931181

full work available at URL

12 December 2024

https://doi.org/10.18632/aging.100382

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21931181

https://europepmc.org/articles/PMC3227450

12 December 2024

file format

HyperText Markup Language

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21931181

https://europepmc.org/articles/PMC3227450?pdf=render

12 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21931181

https://www.aging-us.com/lookup/doi/10.18632/aging.100382

12 December 2024

1 reference

Crossref

DOI

10.18632/AGING.100382

https://api.crossref.org/works/10.18632/AGING.100382

12 December 2024

1 reference

9 August 2017

1 reference

9 August 2017

1 reference

9 August 2017

page(s)

846-851

1 reference

Cytoplasmic dynein in neurodegeneration

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Polo-like kinase 1 phosphorylation of p150 Glued facilitates nuclear envelope breakdown during prophase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

A functional link between polo-like kinase 1 and the mammalian target-of-rapamycin pathway?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

The neuronal cell cycle as a mechanism of pathogenesis in Alzheimer's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Validation of anti-aging drugs by treating age-related diseases

12 July 2018

1 reference

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The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth and chemosensitivity under hypoxic conditions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Aneuploidy, chromosomal missegregation, and cell cycle reentry in Alzheimer's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Plx1 is required for chromosomal DNA replication under stressful conditions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Role for Plk1 phosphorylation of Hbo1 in regulation of replication licensing

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Mouse pre-replicative complex proteins colocalise and interact with the centrosome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Alzheimer disease, the two-hit hypothesis: an update

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Normal cells, but not cancer cells, survive severe Plk1 depletion

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Differential regulation of polo-like kinase 1, 2, 3, and 4 gene expression in mammalian cells and tissues

12 July 2018

1 reference

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Amyloid beta peptide-induced cerebral endothelial cell death involves mitochondrial dysfunction and caspase activation

12 July 2018

1 reference

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Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease.

12 July 2018

1 reference

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Apoptosis and the cell cycle.

12 July 2018

1 reference

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Nerve growth factor increases the sensitivity to zinc toxicity and induces cell cycle arrest in PC12 cells

12 July 2018

1 reference

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Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Neuronal polo-like kinase in Alzheimer disease indicates cell cycle changes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227450

Ectopic cell cycle events link human Alzheimer's disease and amyloid precursor protein transgenic mouse models

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21931181

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/AGING.100382

0 references

PMC publication ID

3227450

1 reference

9 August 2017

1 reference