Modeling pharmacological inhibition of mast cell degranulation as a therapy for insulinoma (Q35581292)

9 August 2017

title

Modeling pharmacological inhibition of mast cell degranulation as a therapy for insulinoma (English)

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9 August 2017

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Laura Soucek

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Joseph J Buggy

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9 August 2017

Roderik Kortlever

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9 August 2017

Shanthi Adimoolam

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9 August 2017

Helena Allende Monclús

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9 August 2017

Maria Teresa Salcedo Allende

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9 August 2017

Lamorna Brown Swigart

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9 August 2017

Gerard I Evan

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9 August 2017

publication date

1 November 2011

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9 August 2017

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

1093-1100

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The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226942

Crosstalk between mast cells and pancreatic cancer cells contributes to pancreatic tumor progression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226942

Immunity, Inflammation, and Cancer

12 July 2018

1 reference

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Cellular and molecular pathways linking inflammation and cancer

12 July 2018

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Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226942

The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1beta

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226942

The inflammatory tumor microenvironment and its impact on cancer development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226942

Integrated signalling pathways for mast-cell activation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226942

Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226942

Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226942

Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors

12 July 2018

1 reference

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Use of both CD63 up regulation and IgE down regulation for the flow cytometric analysis of allergen induced basophil activation. Definition of an activation index.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226942

Reversible kinetic analysis of Myc targets in vivo provides novel insights into Myc-mediated tumorigenesis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226942

Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion

26 September 2018

1 reference

12 December 2020

Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus

1 reference

12 December 2020

Defective degranulation and calcium mobilization of bone-marrow derived mast cells from Xid and Btk-deficient mice

1 reference

12 December 2020

Btk plays a crucial role in the amplification of Fc epsilonRI-mediated mast cell activation by kit

1 reference

12 December 2020

Identifiers

DOI

10.1593/NEO.11980

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9 August 2017

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9 August 2017

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