Unbalanced metabolism of endogenous estrogens in the etiology and prevention of human cancer (Q35580183)

9 August 2017

1 reference

title

Unbalanced metabolism of endogenous estrogens in the etiology and prevention of human cancer (English)

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9 August 2017

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1 reference

Ercole L Cavalieri

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9 August 2017

Eleanor G Rogan

series ordinal

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9 August 2017

publication date

21 March 2011

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The Journal of Steroid Biochemistry and Molecular Biology

9 August 2017

published in

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9 August 2017

volume

125

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9 August 2017

issue

3-5

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9 August 2017

page(s)

169-180

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Evaluation of serum estrogen-DNA adducts as potential biomarkers for breast cancer risk

9 August 2017

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12 July 2018

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12 July 2018

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Inhibition of catechol-O-methyltransferase increases estrogen-DNA adduct formation.

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Formation of depurinating N3Adenine and N7Guanine adducts by MCF-10F cells cultured in the presence of 4-hydroxyestradiol

12 July 2018

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12 July 2018

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17-Beta-estradiol induces transformation and tumorigenesis in human breast epithelial cells

12 July 2018

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Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention

12 July 2018

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The greater reactivity of estradiol-3,4-quinone vs estradiol-2,3-quinone with DNA in the formation of depurinating adducts: implications for tumor-initiating activity

12 July 2018

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The estrogen antagonist ICI-182-780 does not inhibit the transformation phenotypes induced by 17-beta-estradiol and 4-OH estradiol in human breast epithelial cells.

12 July 2018

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12 July 2018

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Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells.

12 July 2018

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Genotoxic metabolites of estradiol in breast: potential mechanism of estradiol induced carcinogenesis

12 July 2018

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Metabolism and DNA binding studies of 4-hydroxyestradiol and estradiol-3,4-quinone in vitro and in female ACI rat mammary gland in vivo

12 July 2018

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12 July 2018

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Spectral characterization of catechol estrogen quinone (CEQ)-derived DNA adducts and their identification in human breast tissue extract

12 July 2018

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Molecular epidemiology of sporadic breast cancer. The role of polymorphic genes involved in oestrogen biosynthesis and metabolism

12 July 2018

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Cancer chemoprevention by resveratrol: in vitro and in vivo studies and the underlying mechanisms (review).

12 July 2018

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Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis

12 July 2018

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Semiquinone radical intermediate in catecholic estrogen-mediated cytotoxicity and mutagenesis: Chemoprevention strategies with antioxidants

12 July 2018

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White button mushroom phytochemicals inhibit aromatase activity and breast cancer cell proliferation

12 July 2018

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Mammary gland development and tumorigenesis in estrogen receptor knockout mice

12 July 2018

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Is estradiol a genotoxic mutagenic carcinogen?

12 July 2018

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Induction of uterine adenocarcinoma in CD-1 mice by catechol estrogens

12 July 2018

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Benzene and non-Hodgkin's lymphoma

12 July 2018

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12 July 2018

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Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells

12 July 2018

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Functional role of estrogen metabolism in target cells: review and perspectives

12 July 2018

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Molecular origin of cancer: Catechol estrogen-3,4-quinones as endogenous tumor initiators

12 July 2018

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12 July 2018

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17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1.

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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26 September 2018

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26 September 2018

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Induction of A.T to G.C mutations by erroneous repair of depurinated DNA following estrogen treatment of the mammary gland of ACI rats

26 September 2018

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Mutagenic activity of 4-hydroxyestradiol, but not 2-hydroxyestradiol, in BB rat2 embryonic cells, and the mutational spectrum of 4-hydroxyestradiol.

26 September 2018

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26 September 2018

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Relative imbalances in the expression of estrogen-metabolizing enzymes in the breast tissue of women with breast carcinoma.

26 September 2018

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Serum sex steroids in premenopausal women and breast cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC).

26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene

26 September 2018

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Catechol estrogen metabolites and conjugates in mammary tumors and hyperplastic tissue from estrogen receptor-alpha knock-out (ERKO)/Wnt-1 mice: implications for initiation of mammary tumors

26 September 2018

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26 September 2018

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Measurement of oxidative DNA damage by catechol estrogens and analogues in vitro.

26 September 2018

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26 September 2018

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Searches for ultimate chemical carcinogens and their reactions with cellular macromolecules.

26 September 2018

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Relative carcinogenic activity of various synthetic and natural estrogens in the Syrian hamster kidney.

26 September 2018

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26 September 2018

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Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients

26 September 2018

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12 December 2020

Potential biomarker for early risk assessment of prostate cancer

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12 December 2020

In situ estrogen production via the estrone sulfatase pathway in breast tumors: relative importance versus the aromatase pathway

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Projecting individualized probabilities of developing breast cancer for white females who are being examined annually

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Polynuclear aromatic compounds. General remarks on the substances considered

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12 December 2020

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Molecular characteristics of catechol estrogen quinones in reactions with deoxyribonucleosides

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12 December 2020

Comparison of estrogen concentrations, estrone sulfatase and aromatase activities in normal, and in cancerous, human breast tissues

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12 December 2020

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12 December 2020

The importance of local synthesis of estrogen within the breast

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12 December 2020

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: evidence for induction of a novel 17 beta-estradiol 4-hydroxylase

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12 December 2020

Is Estradiol a Genotoxic Mutagenic Carcinogen?1

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Identifiers

DOI

1 reference

9 August 2017

1 reference

9 August 2017

1 reference