Differences in the disposition of silymarin between patients with nonalcoholic fatty liver disease and chronic hepatitis C. (Q35579547)

9 August 2017

title

Differences in the disposition of silymarin between patients with nonalcoholic fatty liver disease and chronic hepatitis C. (English)

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metabolic dysfunction–associated steatotic liver disease

9 August 2017

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Abdus S Wahed

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Nezam H Afdhal

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K Rajender Reddy

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9 August 2017

Sarah J Schrieber

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9 August 2017

Roy L Hawke

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9 August 2017

Zhiming Wen

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9 August 2017

Philip C Smith

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9 August 2017

Steven H Belle

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9 August 2017

Victor J Navarro

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9 August 2017

Catherine M Meyers

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9 August 2017

Edward Doo

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9 August 2017

Michael W Fried

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9 August 2017

language of work or name

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24 August 2011

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Drug Metabolism and Disposition

9 August 2017

published in

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

2182-2190

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Silymarin use and liver disease progression in the Hepatitis C Antiviral Long‐Term Treatment against Cirrhosis trial

9 August 2017

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27 July 2018

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Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

26 September 2018

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Coordinate regulation of metabolic enzymes and transporters by nuclear transcription factors in human liver disease

26 September 2018

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Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: role of multidrug resistance-associated protein 2 (Abcc2).

26 September 2018

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The pharmacokinetics of silymarin is altered in patients with hepatitis C virus and nonalcoholic Fatty liver disease and correlates with plasma caspase-3/7 activity

26 September 2018

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Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases

26 September 2018

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Oxidative stress and enzymatic antioxidant status in patients with nonalcoholic steatohepatitis

26 September 2018

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Complete isolation and characterization of silybins and isosilybins from milk thistle (Silybum marianum).

26 September 2018

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Effect of hepatic impairment on the pharmacokinetics of atomoxetine and its metabolites

26 September 2018

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Oxidative stress in chronic hepatitis C: not just a feature of late stage disease.

26 September 2018

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Steatohepatitis: a tale of two "hits"?

26 September 2018

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UDP glucuronosyltransferase mRNA levels in human liver disease

26 September 2018

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12 December 2020

Evidence for differences in regioselective and stereoselective glucuronidation of silybin diastereomers from milk thistle (Silybum marianum) by human UDP-glucuronosyltransferases

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12 December 2020

Substituent effects in the free radical reactions of silybin: radiation-induced oxidation of the flavonoid at neutral pH

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12 December 2020

Efflux transporter expression and acetaminophen metabolite excretion are altered in rodent models of nonalcoholic fatty liver disease

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12 December 2020

Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract

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12 December 2020

Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease

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12 December 2020

Identifiers

DOI

10.1124/DMD.111.040212

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9 August 2017

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9 August 2017

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