The role of Rel/NF-kappaB transcription factors in B lymphocyte survival (Q35561576)

8 August 2017

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title

The role of Rel/NF-kappaB transcription factors in B lymphocyte survival (English)

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8 August 2017

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Andreas Strasser

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Steve Gerondakis

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8 August 2017

language of work or name

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1 June 2003

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8 August 2017

published in

Seminars in Immunology

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8 August 2017

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8 August 2017

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8 August 2017

page(s)

159-166

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The NF-kappa B and I kappa B proteins: new discoveries and insights

8 August 2017

cites work

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7 January 2021

IκB proteins: structure, function and regulation

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7 January 2021

How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

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7 January 2021

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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7 January 2021

Missing pieces in the NF-kappaB puzzle

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7 January 2021

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

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7 January 2021

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

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7 January 2021

BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2

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7 January 2021

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

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7 January 2021

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

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7 January 2021

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7 January 2021

Signaling for survival and apoptosis in the immune system

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7 January 2021

The turnover of B-cell populations

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7 January 2021

Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts

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7 January 2021

Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture

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7 January 2021

Nuclear factor kappa B is required for the development of marginal zone B lymphocytes

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7 January 2021

The combined absence of NF-kappa B1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells

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7 January 2021

B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells

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7 January 2021

IkappaB kinase alpha is essential for mature B cell development and function

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7 January 2021

IkappaB kinase signaling is essential for maintenance of mature B cells

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7 January 2021

Failure of lymphopoiesis after adoptive transfer of NF-kappaB-deficient fetal liver cells

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7 January 2021

Requirement for NF-κB in osteoclast and B-cell development

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7 January 2021

The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression

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7 January 2021

Rel/NF-kappaB transcription factors: key mediators of B-cell activation

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7 January 2021

BCL-2 family: regulators of cell death

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7 January 2021

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

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7 January 2021

bcl-x exhibits regulated expression during B cell development and activation and modulates lymphocyte survival in transgenic mice.

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7 January 2021

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

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7 January 2021

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

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7 January 2021

Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene.

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7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

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7 January 2021

BAFF: a fundamental survival factor for B cells.

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7 January 2021

Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

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7 January 2021

TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS

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7 January 2021

Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency

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7 January 2021

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

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7 January 2021

Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure

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7 January 2021

Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

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7 January 2021

c-Rel is required for the protection of B cells from antigen receptor-mediated, but not Fas-mediated, apoptosis

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7 January 2021

The Bcl-2 protein family: arbiters of cell survival

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7 January 2021

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

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7 January 2021

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

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7 January 2021

10.1016/S1044-5323(03)00036-8

Identifiers

DOI

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8 August 2017

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