TCF7L2: the biggest story in diabetes genetics since HLA? (Q35566632)

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21 December 2019

title

TCF7L2: the biggest story in diabetes genetics since HLA? (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17096114%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17096114%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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21 December 2019

M I McCarthy

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PubMed publication ID

17096114

8 August 2017

publication date

1 January 2007

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21 December 2019

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21 December 2019

volume

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21 December 2019

issue

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21 December 2019

page(s)

1-4

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Analysis of the type 2 diabetes gene, TCF7L2, in 13,795 type 1 diabetes cases and control subjects

21 December 2019

cites work

1 reference

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Combining information from common type 2 diabetes risk polymorphisms improves disease prediction

27 July 2018

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TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

27 July 2018

1 reference

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Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

27 July 2018

1 reference

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Genome-wide association studies: theoretical and practical concerns

27 July 2018

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Progress in defining the molecular basis of type 2 diabetes mellitus through susceptibility-gene identification

27 July 2018

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Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2.

27 July 2018

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Maturity-onset diabetes of the young: from clinical description to molecular genetic characterization

27 July 2018

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The accelerator hypothesis: weight gain as the missing link between Type I and Type II diabetes

27 July 2018

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A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q

27 July 2018

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The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

27 July 2018

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Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population.

27 July 2018

1 reference

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Association of variants of transcription factor 7-like 2 (TCF7L2) with susceptibility to type 2 diabetes in the Dutch Breda cohort

26 September 2018

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Predictive genetic testing for type 2 diabetes

26 September 2018

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Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in the Amish: replication and evidence for a role in both insulin secretion and insulin resistance.

26 September 2018

1 reference

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Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations

26 September 2018

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How many genes underlie the occurrence of common complex diseases in the population?

26 September 2018

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Revisiting the clinical validity of multiplex genetic testing in complex diseases

26 September 2018

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Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

26 September 2018

1 reference

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No major contribution of TCF7L2 sequence variants to maturity onset of diabetes of the young (MODY) or neonatal diabetes mellitus in French white subjects

26 September 2018

1 reference

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Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human -Cells and Adipose Tissue and Strong Association With Type 2 Diabetes

24 October 2018

1 reference

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Association of Transcription Factor 7-Like 2 (TCF7L2) Variants With Type 2 Diabetes in a Finnish Sample

7 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760757

Variant of Transcription Factor 7-Like 2 (TCF7L2) Gene and the Risk of Type 2 Diabetes in Large Cohorts of U.S. Women and Men

7 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760757

Association Analysis of 6,736 U.K. Subjects Provides Replication and ConfirmsTCF7L2as a Type 2 Diabetes Susceptibility Gene With a Substantial Effect on Individual Risk

7 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760757

Will Genetics Revolutionize Medicine?

7 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1760757

Can twin studies assess the genetic component in type 2 (non-insulin-dependent) diabetes mellitus?

7 December 2018

1 reference

12 December 2020

Making the right associations

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12 December 2020

What makes a good genetic association study?

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12 December 2020

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals

1 reference

12 December 2020

The double helix in clinical practice

1 reference

12 December 2020

10.1007/S00125-006-0507-X

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17096114%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17096114%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

PubMed publication ID

17096114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17096114%20AND%20SRC:MED&resulttype=core&format=json