Interconversion of Functional Activity by Minor Structural Alterations in Nonpeptide AT2 Receptor Ligands (Q35564416)

8 August 2017

title

Interconversion of Functional Activity by Minor Structural Alterations in Nonpeptide AT2 Receptor Ligands (English)

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8 August 2017

Marie-Odile Guimond

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8 August 2017

Nicole Gallo-Payet

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8 August 2017

Mathias Alterman

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8 August 2017

Charlotta Wallinder

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8 August 2017

Milad Botros

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8 August 2017

Christian Sköld

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8 August 2017

Mathias Hallberg

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8 August 2017

Anders Karlén

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8 August 2017

publication date

8 December 2014

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ACS Medicinal Chemistry Letters

8 August 2017

published in

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8 August 2017

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8 August 2017

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8 August 2017

page(s)

178-182

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EMA401, an orally administered highly selective angiotensin II type 2 receptor antagonist, as a novel treatment for postherpetic neuralgia: a randomised, double-blind, placebo-controlled phase 2 clinical trial

8 August 2017

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Angiotensin type 2 receptor stimulation ameliorates left ventricular fibrosis and dysfunction via regulation of tissue inhibitor of matrix metalloproteinase 1/matrix metalloproteinase 9 axis and transforming growth factor β1 in the rat heart

27 July 2018

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Update on the angiotensin AT(2) receptor.

27 July 2018

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Comparative functional properties of two structurally similar selective nonpeptide drug-like ligands for the angiotensin II type-2 (AT(2)) receptor. Effects on neurite outgrowth in NG108-15 cells

27 July 2018

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AT2 receptors: beneficial counter-regulatory role in cardiovascular and renal function

27 July 2018

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From the first selective non-peptide AT(2) receptor agonist to structurally related antagonists

27 July 2018

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27 July 2018

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Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships

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27 July 2018

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Selective angiotensin II AT2 receptor agonists: arylbenzylimidazole structure-activity relationships

27 July 2018

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The AT2 receptor--a matter of love and hate

27 July 2018

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27 July 2018

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Agonistic and antagonistic properties of angiotensin analogs at the AT2 receptor in PC12W cells

27 July 2018

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The angiotensin AT2 receptor modulates T-type calcium current in non-differentiated NG108-15 cells

27 July 2018

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Expression and role of the angiotensin II AT2 receptor in human prostate tissue: in search of a new therapeutic option for prostate cancer

27 July 2018

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Perspective: A tale of two receptors.

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Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage

26 September 2018

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Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction?

26 September 2018

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Nitric oxide and cyclic GMP are involved in angiotensin II AT(2) receptor effects on neurite outgrowth in NG108-15 cells

26 September 2018

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Signals from the AT2 (angiotensin type 2) receptor of angiotensin II inhibit p21ras and activate MAPK (mitogen-activated protein kinase) to induce morphological neuronal differentiation in NG108-15 cells

26 September 2018

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A fast new approach to pharmacophore mapping and its application to dopaminergic and benzodiazepine agonists.

26 September 2018

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Angiotensin II receptors and renin in the porcine uterus: myometrial AT2 and endometrial AT1 receptors are down-regulated during gestation

26 September 2018

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12 December 2020

Dual agonistic and antagonistic property of nonpeptide angiotensin AT1 ligands: susceptibility to receptor mutations

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12 December 2020

Angiotensin II induction of neurite outgrowth by AT2 receptors in NG108-15 cells. Effect counteracted by the AT1 receptors

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12 December 2020

Synthesis of some analogs of angiotensin II as specific antagonists of the parent hormone

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12 December 2020

Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives

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12 December 2020

Identifiers

DOI

10.1021/ML500427R

1 reference

release_kkjsjwyjpffplhh5craxvj6nsm

8 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kkjsjwyjpffplhh5craxvj6nsm

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4329586

1 reference

8 August 2017

1 reference