Paeoniflorin attenuates neuroinflammation and dopaminergic neurodegeneration in the MPTP model of Parkinson's disease by activation of adenosine A1 receptor (Q35545909)

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scientific article published on June 2006

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English	Paeoniflorin attenuates neuroinflammation and dopaminergic neurodegeneration in the MPTP model of Parkinson's disease by activation of adenosine A1 receptor	scientific article published on June 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Paeoniflorin attenuates neuroinflammation and dopaminergic neurodegeneration in the MPTP model of Parkinson's disease by activation of adenosine A1 receptor (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

0 references

1 reference

based on heuristic

inferred from title

Parkinson's disease

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based on heuristic

inferred from title

neurodegeneration

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based on heuristic

inferred from title

author name string

Hua-Qing Liu

1

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Wei-Yu Zhang

2

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Europe PubMed Central

PubMed publication ID

8 August 2017

Xue-Ting Luo

3

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Yang Ye

4

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Xing-Zu Zhu

5

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Europe PubMed Central

PubMed publication ID

8 August 2017

language of work or name

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publication date

1 June 2006

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Europe PubMed Central

PubMed publication ID

8 August 2017

British Journal of Pharmacology

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Europe PubMed Central

PubMed publication ID

8 August 2017

148

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Europe PubMed Central

PubMed publication ID

8 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

314-325

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Europe PubMed Central

PubMed publication ID

8 August 2017

Neuroprotective effect of paeoniflorin on cerebral ischemic rat by activating adenosine A1 receptor in a manner different from its classical agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

12 July 2018

Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease

1 reference

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12 July 2018

Novel anti-inflammatory therapy for Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

12 July 2018

Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinases

1 reference

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12 July 2018

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

12 July 2018

Neuroinflammatory processes in Parkinson's disease.

1 reference

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12 July 2018

Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention.

1 reference

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12 July 2018

Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.

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12 July 2018

MPTP and 6-hydroxydopamine-induced neurodegeneration as models for Parkinson's disease: neuroprotective strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

12 July 2018

Paeoniflorin reverses guanethidine-induced hypotension via activation of central adenosine A1 receptors in Wistar rats

1 reference

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12 July 2018

Agonists of A1 and A2A adenosine receptors attenuate methamphetamine-induced overflow of dopamine in rat striatum

1 reference

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12 July 2018

Experimental developments in movement disorders: update on proposed free radical mechanisms

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12 July 2018

Antihyperglycemic Effects of Paeoniflorin and 8-Debenzoylpaeoniflorin, Glucosides from the Root ofPaeonia lactiflora

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

12 July 2018

Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

12 July 2018

Cytokines in inflammatory brain lesions: helpful and harmful

1 reference

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12 July 2018

Microglia: a sensor for pathological events in the CNS

1 reference

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12 July 2018

Inhibition of TNF-alpha expression by adenosine: role of A3 adenosine receptors

1 reference

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12 July 2018

Adenosine receptor subtypes

1 reference

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12 July 2018

Adenosine, an endogenous anti-inflammatory agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

12 July 2018

Adenosine receptor subtypes: characterization and therapeutic regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

12 July 2018

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

12 July 2018

The cellular localization of adenosine receptors in rat neostriatum

1 reference

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12 July 2018

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

1 reference

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12 July 2018

Physiological and pharmacological properties of adenosine: therapeutic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

12 July 2018

A consideration of neural counting methods

1 reference

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12 July 2018

Stereology: the fast lane between neuroanatomy and brain function--or still only a tightrope?

1 reference

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12 July 2018

Neuroprotective role of adenosine in cerebral ischaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

12 July 2018

A role of IL-1 in MPTP-induced changes in striatal dopaminergic and serotoninergic transporter binding: clues from interleukin-1 type I receptor-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6-methyl-phenyl-tetrahydropyridine toxicity

1 reference

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26 September 2018

Triptolide protects dopaminergic neurons from inflammation-mediated damage induced by lipopolysaccharide intranigral injection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

Interleukine-1beta and interleukine-6 levels in striatum and other brain structures after MPTP treatment: influence of behavioral lateralization

1 reference

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26 September 2018

Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTP neurotoxicity in mice

1 reference

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26 September 2018

Biochemical, behavioral and immunohistochemical alterations in MPTP-treated mouse model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

Genetic ablation of tumor necrosis factor-alpha (TNF-alpha) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum

1 reference

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26 September 2018

Caspase-11 mediates inflammatory dopaminergic cell death in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis.

1 reference

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26 September 2018

Adenosinergic protection of dopaminergic and GABAergic neurons against mitochondrial inhibition through receptors located in the substantia nigra and striatum, respectively.

1 reference

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26 September 2018

Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease.

1 reference

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26 September 2018

Stimulatory Effect of Paeoniflorin on Adenosine Release to Increase the Glucose Uptake into White Adipocytes of Wistar Rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

Diminished adenosine A1 receptor expression on macrophages in brain and blood of patients with multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

Nitric oxide synthase inhibitors cause motor deficits in mice

1 reference

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26 September 2018

Morphology of reactive microglia in the injured cerebral cortex. Fractal analysis and complementary quantitative methods

1 reference

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26 September 2018

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

The inflammatory reaction following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication in mouse

1 reference

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26 September 2018

Microglial and astrocytic involvement in a murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

Effects of repeated systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to mice on interleukin-1beta and nerve growth factor in the striatum

1 reference

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26 September 2018

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1 reference

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26 September 2018

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1 reference

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26 September 2018

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26 September 2018

Pole test is a useful method for evaluating the mouse movement disorder caused by striatal dopamine depletion

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

Protection against acute MPTP-induced dopamine depletion in mice by adenosine A1 agonist

1 reference

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26 September 2018

Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

Biologically active principles of crude drugs. II. Anti-allergic principles in "SHOSEIRYU-TO" anti-inflammatory properties of paeoniflorin and its derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1751566

26 September 2018

Absorption and excretion of paeoniflorin in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

8-Alkylamino-substituted analogs of N6-cyclopentyladenosine are partial agonists for the cardiovascular adenosine A1 receptors in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulatory effect of paeoniflorin on adenosine A-1 receptors to increase the translocation of protein kinase C (PKC) and glucose transporter (GLUT 4) in isolated rat white adipocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulatory effects of adenosine on cytokine release by activated human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine and cerebral ischemia: therapeutic future or death of a brave concept?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of adenosine receptor agents on the expression of morphine withdrawal in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoid receptor-nitric oxide crosstalk and vulnerability to experimental parkinsonism: pivotal role for glia-neuron interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

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Neuroprotective effects of a novel poly(ADP-ribose) polymerase-1 inhibitor, 2-[3-[4-(4-chlorophenyl)-1-piperazinyl] propyl]-4(3H)-quinazolinone (FR255595), in an in vitro model of cell death and in mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

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Studies on the combination of Glycyrrhizae Radix in Shakuyakukanzo-To

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

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1 reference

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12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine: does it have a neuroprotective role after all?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroglial responses to the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complementary effects of paeoniflorin and glycyrrhizin on intracellular Ca2+ mobilization in the nerve-stimulated skeletal muscle of mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine enhances IL-10 secretion by human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16582933

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diminished adenosine A1 receptor expression on macrophages in brain and blood of patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0706732

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/SJ.BJP.0706732

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

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