Ubiquitous transgene expression of the glucosylceramide-synthesizing enzyme accelerates glucosylceramide accumulation and storage cells in a Gaucher disease mouse model (Q35536435)

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scientific article published on 31 December 2014

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English	Ubiquitous transgene expression of the glucosylceramide-synthesizing enzyme accelerates glucosylceramide accumulation and storage cells in a Gaucher disease mouse model	scientific article published on 31 December 2014

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 August 2017

Ubiquitous transgene expression of the glucosylceramide-synthesizing enzyme accelerates glucosylceramide accumulation and storage cells in a Gaucher disease mouse model (English)

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Europe PubMed Central

PubMed publication ID

8 August 2017

author name string

Sonya Barnes

1

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PubMed publication ID

8 August 2017

You-Hai Xu

2

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PubMed publication ID

8 August 2017

Wujuan Zhang

3

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Europe PubMed Central

PubMed publication ID

8 August 2017

Benjamin Liou

4

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8 August 2017

Kenneth D R Setchell

5

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8 August 2017

Liming Bao

6

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8 August 2017

Gregory A Grabowski

7

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8 August 2017

Ying Sun

8

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8 August 2017

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publication date

31 December 2014

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8 August 2017

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8 August 2017

9

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8 August 2017

12

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8 August 2017

e116023

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Europe PubMed Central

PubMed publication ID

8 August 2017

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Creative Commons Attribution 4.0 International

31 December 2014

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April 2022 Public Data File from Crossref

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0 references

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Novel mutations in the glucocerebrosidase gene of Indian patients with Gaucher disease.

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Neuronal expression of glucosylceramide synthase in central nervous system regulates body weight and energy homeostasis.

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Improved management of lysosomal glucosylceramide levels in a mouse model of type 1 Gaucher disease using enzyme and substrate reduction therapy

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Multi-system disorders of glycosphingolipid and ganglioside metabolism

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Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

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27 July 2018

Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate

1 reference

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Dependence of reversibility and progression of mouse neuronopathic Gaucher disease on acid beta-glucosidase residual activity levels

1 reference

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27 July 2018

Gaucher disease: mutation and polymorphism spectrum in the glucocerebrosidase gene (GBA).

1 reference

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Functions of sphingolipid metabolism in mammals--lessons from genetic defects.

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Murine models of acute neuronopathic Gaucher disease

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Pre- and post-Golgi translocation of glucosylceramide in glycosphingolipid synthesis.

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Recycling of sphingosine is regulated by the concerted actions of sphingosine-1-phosphate phosphohydrolase 1 and sphingosine kinase 2.

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Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide

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Gaucher disease among Chinese patients: review on genotype/phenotype correlation from 29 patients and identification of novel and rare alleles

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Gaucher disease: complexity in a "simple" disorder

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Glycosphingolipids in engineered mice: insights into function

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Viable mouse models of acid beta-glucosidase deficiency: the defect in Gaucher disease

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Systemic inflammation in glucocerebrosidase-deficient mice with minimal glucosylceramide storage

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Inhibition of substrate synthesis as a strategy for glycolipid lysosomal storage disease therapy

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A vital role for glycosphingolipid synthesis during development and differentiation

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Translational inefficiency of acid beta-glucosidase mRNA in transgenic mammalian cells

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Variations among cell lines in the synthesis of sphingolipids in de novo and recycling pathways

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Phenotype of arylsulfatase A-deficient mice: relationship to human metachromatic leukodystrophy

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Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis

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Identifiers

10.1371/JOURNAL.PONE.0116023

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

2014PLoSO...9k6023B

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

ResearchGate publication ID

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