Caspase-8 inactivation in T cells increases necroptosis and suppresses autoimmunity in Bim-/- mice (Q35406486)

8 August 2017

title

Caspase-8 inactivation in T cells increases necroptosis and suppresses autoimmunity in Bim-/- mice (English)

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8 August 2017

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Leonardo Salmena

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Andreas Strasser

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Toshiyuki Bohgaki

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8 August 2017

Julien Mozo

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8 August 2017

Elzbieta Matysiak-Zablocki

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8 August 2017

Miyuki Bohgaki

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8 August 2017

Otto Sanchez

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8 August 2017

Anne Hakem

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8 August 2017

Razqallah Hakem

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8 August 2017

language of work or name

English

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publication date

1 October 2011

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8 August 2017

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inferred from page(s)

published in

Journal of Cell Biology

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8 August 2017

volume

195

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8 August 2017

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8 August 2017

page(s)

277-291

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Mechanisms of necroptosis in T cells

8 August 2017

cites work

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

12 July 2018

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Selection of the T cell repertoire.

12 July 2018

1 reference

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Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

12 July 2018

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A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

12 July 2018

1 reference

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Fas and Fas ligand: lpr and gld mutations

12 July 2018

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Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

12 July 2018

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Critical roles of Bim in T cell activation and T cell-mediated autoimmune inflammation in mice

12 July 2018

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Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction

26 September 2018

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A role for caspases in controlling IL-4 expression in T cells

26 September 2018

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Autophagy induction and autophagic cell death in effector T cells

26 September 2018

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12 December 2020

Essential role for caspase-8 in Toll-like receptors and NFkappaB signaling

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12 December 2020

Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity

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12 December 2020

Interaction of mutant lpr gene with background strain influences renal disease

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12 December 2020

Identifiers

DOI

10.1083/JCB.201103053

1 reference

8 August 2017

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8 August 2017

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