Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences. (Q35356784)

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English	Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences.	scientific article

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9 February 2020

Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences (English)

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9 February 2020

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Nicolas Narboux-Nême

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9 February 2020

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Patricia Gaspar

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Stephane Doly

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Silvina L Diaz

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Cédric B P Martin

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9 February 2020

Gaelle Angenard

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9 February 2020

Marie-Pascale Martres

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Michel Hamon

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9 February 2020

Laurence Lanfumey

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Raymond Mongeau

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3 August 2011

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9 February 2020

Neuropsychopharmacology

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9 February 2020

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9 February 2020

2538-2550

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11 June 2022

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Genetic models of serotonin (5-HT) depletion: what do they tell us about the developmental role of 5-HT?

1 reference

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Growth retardation and altered autonomic control in mice lacking brain serotonin

1 reference

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Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants

1 reference

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Enhanced contextual fear memory in central serotonin-deficient mice

1 reference

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Role of GSK3 beta in behavioral abnormalities induced by serotonin deficiency

1 reference

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Nonvesicular inhibitory neurotransmission via reversal of the GABA transporter GAT-1.

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5-HT2 receptor activation in the midbrain periaqueductal grey (PAG) reduces anxiety-like behaviour in mice

1 reference

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Serotonin 5-HT(2C) receptors regulate anxiety-like behavior

1 reference

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Anxiogenic-like effects of mCPP microinfusions into the amygdala (but not dorsal or ventral hippocampus) in mice exposed to elevated plus-maze.

1 reference

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Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain

1 reference

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New approaches to antidepressant drug discovery: beyond monoamines

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The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice

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Serotonin, the periaqueductal gray and panic

1 reference

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Antidepressants and brain monoaminergic systems: a dimensional approach to understanding their behavioural effects in depression and anxiety disorders

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Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function

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The vesicular monoamine content regulates VMAT2 activity through Galphaq in mouse platelets. Evidence for autoregulation of vesicular transmitter uptake

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Pet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxiety-like and aggressive behavior.

1 reference

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Effects of genetic depletion of monoamines on somatosensory cortical development.

1 reference

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Paracrine neurotransmission in the CNS: involvement of 5-HT.

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A microdialysis study of the in vivo release of 5-HT in the median raphe nucleus of the rat.

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Effect of fluoxetine on extracellular 5-hydroxytryptamine in rat brain. Role of 5-HT autoreceptors

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Behavioral effects of phenelzine in an experimental model for screening anxiolytic and anti-panic drugs: correlation with changes in monoamine-oxidase activity and monoamine levels

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The spectrum of behaviors influenced by serotonin

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27 July 2018

Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine.

1 reference

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27 July 2018

5-HT systems and anxiety: multiple mechanisms in the elevated X-maze

1 reference

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Pharmacological manipulation of ultrasound induced defence behaviour in the rat.

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Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter

1 reference

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Functional identification and molecular cloning of a human brain vesicle monoamine transporter

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27 July 2018

Nonvesicular release of neurotransmitter.

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5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: More than 30 years of research

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The mechanism by which monoamine oxidase inhibitors give rise to a non-calcium-dependent component in the depolarization-induced release of 5-HT from rat brain synaptosomes

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27 July 2018

Modification of vesicular dopamine and norepinephrine by monoamine oxidase inhibitors

1 reference

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5-hydroxytryptamine uptake blockers attenuate the 5-hydroxytryptamine-releasing effect of 3,4-methylenedioxymethamphetamine and related agents

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A genetically defined morphologically and functionally unique subset of 5-HT neurons in the mouse raphe nuclei.

1 reference

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5-HT2C receptor activation prevents stress-induced enhancement of brain 5-HT turnover and extracellular levels in the mouse brain: modulation by chronic paroxetine treatment

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1 reference

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1 reference

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1 reference

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1 reference

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26 September 2018

Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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p-chlorophenylalanine-induced serotonin depletion: reduction in exploratory locomotion but no obvious sensory-motor deficits

1 reference

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Inhibition of median and dorsal raphe neurones following administration of the selective serotonin reuptake inhibitor paroxetine

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21814181

12 December 2020

based on heuristic

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The serotonergic and noradrenergic systems of the hippocampus: their interactions and the effects of antidepressant treatments

1 reference

https://pubmed.ncbi.nlm.nih.gov/21814181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered expression and functions of serotonin 5-HT1Aand 5-HT1Breceptors in knock-out mice lacking the 5-HT transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/21814181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential inhibition of serotonin release by 5-HT and NA reuptake blockers after systemic administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/21814181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible monoamine oxidase-A inhibitors in panic disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/21814181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1038/NPP.2011.142

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9 February 2020

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9 February 2020

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9 February 2020

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