Inhibition of autophagy potentiates the efficacy of Gli inhibitor GANT-61 in MYCN-amplified neuroblastoma cells (Q35342521)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25323222%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Inhibition of autophagy potentiates the efficacy of Gli inhibitor GANT-61 in MYCN-amplified neuroblastoma cells (English)

1 reference

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21 February 2020

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1 reference

1 reference

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21 February 2020

Jing Wang

1 reference

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21 February 2020

Song Gu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25323222%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Jun Huang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25323222%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Sheng Chen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25323222%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Min Xu

1 reference

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21 February 2020

language of work or name

English

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publication date

17 October 2014

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21 February 2020

1 reference

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21 February 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25323222%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

page(s)

768

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25323222%20AND%20SRC:MED&resulttype=core&format=json

Therapeutic targets for neuroblastomas

21 February 2020

cites work

1 reference

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Histone deacetylase 10 promotes autophagy-mediated cell survival.

12 July 2018

1 reference

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Guggulsterone sensitizes glioblastoma cells to Sonic hedgehog inhibitor SANT-1 induced apoptosis in a Ras/NFκB dependent manner

12 July 2018

1 reference

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The Hedgehog signalling pathway regulates autophagy.

12 July 2018

1 reference

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Sonic hedgehog promotes autophagy of vascular smooth muscle cells

12 July 2018

1 reference

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Regulation of inflammatory response by 3-methyladenine involves the coordinative actions on Akt and glycogen synthase kinase 3β rather than autophagy

12 July 2018

1 reference

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Regulation and function of autophagy during cell survival and cell death.

12 July 2018

1 reference

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Sonic Hedgehog pathway is essential for neuroblastoma cell proliferation and tumor growth

12 July 2018

1 reference

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The MYCN oncogene and differentiation in neuroblastoma

12 July 2018

1 reference

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Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells.

12 July 2018

1 reference

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Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells

12 July 2018

1 reference

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Autophagy and the Integrated Stress Response

12 July 2018

1 reference

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Hedgehog beyond medulloblastoma and basal cell carcinoma

12 July 2018

1 reference

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A critical role of Sonic Hedgehog signaling in maintaining the tumorigenicity of neuroblastoma cells

12 July 2018

1 reference

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The paradox of autophagy and its implication in cancer etiology and therapy

12 July 2018

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Neuroblastoma: biology, prognosis, and treatment

12 July 2018

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Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

12 July 2018

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Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

12 July 2018

1 reference

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The MYCN enigma: significance of MYCN expression in neuroblastoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4210511

Deregulation of the hedgehog signalling pathway: a possible role for the PTCH and SUFU genes in human rhabdomyoma and rhabdomyosarcoma development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4210511

The role of autophagy in cancer development and response to therapy.

12 July 2018

1 reference

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Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4210511

Autophagy: in sickness and in health

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4210511

Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4210511

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4210511

Hedgehog signaling in animal development: paradigms and principles

12 July 2018

1 reference

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Inhibition of N-myc expression and induction of apoptosis by iron chelation in human neuroblastoma cells.

12 July 2018

1 reference

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Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

12 July 2018

1 reference

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Gli proteins and Hedgehog signaling: development and cancer

12 July 2018

1 reference

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MycN sensitizes neuroblastoma cells for drug-induced apoptosis

12 July 2018

1 reference

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Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

12 July 2018

1 reference

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Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo

12 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1471-2407-14-768

Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25323222

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-14-768

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25323222%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

21 February 2020

0 references

1 reference

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21 February 2020

PubMed publication ID

25323222

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25323222%20AND%20SRC:MED&resulttype=core&format=json