Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications. (Q35230177)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25402614%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Efficient delivery of RNAi prodrugs containing reversible charge-neutralizing phosphotriester backbone modifications (English)

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22 February 2020

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22 February 2020

Bryan R Meade

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22 February 2020

Khirud Gogoi

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22 February 2020

Alexander S Hamil

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22 February 2020

Caroline Palm-Apergi

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22 February 2020

Arjen van den Berg

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22 February 2020

Jonathan C Hagopian

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22 February 2020

Aaron D Springer

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22 February 2020

Akiko Eguchi

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22 February 2020

Apollo D Kacsinta

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22 February 2020

Connor F Dowdy

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22 February 2020

Asaf Presente

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22 February 2020

Peter Lönn

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22 February 2020

Naohisa Yoshioka

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22 February 2020

Edwige Gros

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22 February 2020

Xian-Shu Cui

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22 February 2020

Steven F Dowdy

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22 February 2020

publication date

17 November 2014

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22 February 2020

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22 February 2020

volume

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22 February 2020

issue

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22 February 2020

page(s)

1256-1261

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Delivery materials for siRNA therapeutics

22 February 2020

cites work

1 reference

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Nanoparticle-Based Delivery of RNAi Therapeutics: Progress and Challenges.

27 July 2018

1 reference

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Alkynyl phosphonate DNA: a versatile "click"able backbone for DNA-based biological applications

27 July 2018

1 reference

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Silencing or stimulation? siRNA delivery and the immune system

27 July 2018

1 reference

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Progress toward in vivo use of siRNAs-II

27 July 2018

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Current prospects for RNA interference-based therapies

27 July 2018

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Protein transduction domain delivery of therapeutic macromolecules

27 July 2018

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Chemical Modification of Small Interfering RNA

27 July 2018

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RNA interference in the clinic: challenges and future directions

27 July 2018

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Ancestral roles of small RNAs: an Ago-centric perspective

27 July 2018

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The road to therapeutic RNA interference (RNAi): Tackling the 800 pound siRNA delivery gorilla.

27 July 2018

1 reference

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An overview of chemical processes that damage cellular DNA: spontaneous hydrolysis, alkylation, and reactions with radicals

27 July 2018

1 reference

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Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein

27 July 2018

1 reference

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The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice.

27 July 2018

1 reference

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The promises and pitfalls of RNA-interference-based therapeutics

27 July 2018

1 reference

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Chemical modification of siRNAs for in vivo use.

27 July 2018

1 reference

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Solid-phase synthesis of siRNA oligonucleotides.

27 July 2018

1 reference

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Oligo- and poly-nucleotides: 50 years of chemical synthesis

27 July 2018

1 reference

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SATE pronucleotide approaches: an overview

27 July 2018

1 reference

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Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.

27 July 2018

1 reference

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Solid-phase chemical synthesis of phosphonoacetate and thiophosphonoacetate oligodeoxynucleotides

27 July 2018

1 reference

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

27 July 2018

1 reference

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Intracellular metabolism of beta-L-ddAMP-bis(tbutylSATE), a potent inhibitor of hepatitis B virus replication

27 July 2018

1 reference

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Design and synthesis of novel amphiphilic dendritic galactosides for selective targeting of liposomes to the hepatic asialoglycoprotein receptor.

27 July 2018

1 reference

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The pro-oligonucleotide approach: solid phase synthesis and preliminary evaluation of model pro-dodecathymidylates

27 July 2018

1 reference

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Hydroquinone-O,O'-diacetic acid ('Q-linker') as a replacement for succinyl and oxalyl linker arms in solid phase oligonucleotide synthesis

27 July 2018

1 reference

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Mononucleoside phosphotriester derivatives with S-acyl-2-thioethyl bioreversible phosphate-protecting groups: intracellular delivery of 3'-azido-2',3'-dideoxythymidine 5'-monophosphate

27 July 2018

1 reference

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Synthesis of well-defined phosphate-methylated DNA fragments: the application of potassium carbonate in methanol as deprotecting reagent

27 July 2018

1 reference

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Origins and Mechanisms of miRNAs and siRNAs

27 July 2018

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Recognition and catalysis in nucleic acid chemistry

21 January 2018

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siRNA and innate immunity

21 January 2018

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Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo

21 January 2018

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Synthesis of chimeric oligonucleotides containing internucleosidic phosphodiester and S-pivaloylthioethyl phosphotriester residues

21 January 2018

1 reference

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The 2-(N-formyl-N-methyl)aminoethyl group as a potential phosphate/thiophosphate protecting group in solid-phase oligodeoxyribonucleotide synthesis

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25402614

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NBT.3078

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22 February 2020

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22 February 2020

PubMed publication ID

25402614

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